product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TfR (Transferrin R) Antibody
catalog :
AF2474
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, neutralization, immunohistochemistry - frozen section
more info or order :
citations: 6
Reference
Bailey D, Clark W, Kosman D. The iron chelator, PBT434, modulates transcellular iron trafficking in brain microvascular endothelial cells. PLoS ONE. 2021;16:e0254794 pubmed publisher
Yamamoto R, Yoden E, Tanaka N, Kinoshita M, Imakiire A, Hirato T, et al. Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolysaccharidosis type II. Mol Genet Metab Rep. 2021;27:100758 pubmed publisher
Rhee J, Yi H, Thomas D, Lam C, Belbachir N, Tian L, et al. Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cell Rep. 2020;32:107886 pubmed publisher
Scheiber I, Alarcon N, Zhao N. Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14. Nutrients. 2019;11: pubmed publisher
Spence J, He R, Hoffmann H, Das T, Thinon E, Rice C, et al. IFITM3 directly engages and shuttles incoming virus particles to lysosomes. Nat Chem Biol. 2019;15:259-268 pubmed publisher
Ramanathan A, Gusarova V, Stahl N, Gurnett Bander A, Kyratsous C. Alirocumab, a Therapeutic Human Antibody to PCSK9, Does Not Affect CD81 Levels or Hepatitis C Virus Entry and Replication into Hepatocytes. PLoS ONE. 2016;11:e0154498 pubmed publisher
product information
brand :
R&D Systems
master code :
AF2474
SKU :
AF2474
product name :
Human TfR (Transferrin R) Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human TfR (Transferrin R) Antibody from R&D Systems is a goat polyclonal antibody to TfR (Transferrin R). This antibody reacts with human,mouse,transgenic mouse. The Human TfR (Transferrin R) Antibody has been validated for the following applications: Western Blot,Surface Plasmon Resonance,Neutralization,Immunohistochemistry-Frozen,Immunohistochemistry,Blockade of Receptor-ligand Interaction.
target :
TfR (Transferrin R)
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.25 ug/mL, Immunohistochemistry 5-15 ug/mL, Blockade of Receptor-ligand Interaction
host :
Goat
immunogen :
Human placenta-derived TfR (Transferrin R)
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects human TfR (Transferrin R) in direct ELISAs and Western blots.
gene symbol :
TFRC
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human TfR (Transferrin R) antibody by Western Blot.
applications :
Immunohistochemistry,Blockade of Receptor-ligand Interaction,Western Blot,Immunohistochemistry-Frozen,Surface Plasmon Resonance,Neutralization
USD :
509 USD
alt names :
CD71, CD71 antigen, CD71TRFR, p90, T9, TfR, TfR (TransferrinR), TFR1, TFRC, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.