Human IFN-alpha/▀ R1 Antibody | R&D Systems AF245 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IFN-alpha/▀ R1 Antibody

catalog :

AF245

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, neutralization, flow cytometry, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig 7e	Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko L, et al. A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants. Cell Stem Cell. 2022;29:1475-1490.e6 pubmed publisher
	Kramer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga García R, et al. Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. Immunity. 2021;54:2650-2669.e14 pubmed publisher
	Rueschenbaum S, Cai C, Schmidt M, Schwarzkopf K, Dittmer U, Zeuzem S, et al. Translation of IRF-1 Restricts Hepatic Interleukin-7 Production to Types I and II Interferons: Implications for Hepatic Immunity. Front Immunol. 2020;11:581352 pubmed publisher
	Sullivan K, Lewis H, Hill A, Pandey A, Jackson L, Cabral J, et al. Trisomy 21 consistently activates the interferon response. elife. 2016;5: pubmed publisher

product information

brand :

R&D Systems

master code :

AF245

SKU :

AF245

product name :

Human IFN-alpha/▀ R1 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human IFN-alpha/ß R1 Antibody from R&D Systems is a goat polyclonal antibody to IFN-alpha/beta R1. This antibody reacts with human,mouse. The Human IFN-alpha/ß R1 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization,Immunocytochemistry,CyTOF-ready.

target :

IFN-alpha/beta R1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1-1 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, CyTOF-ready

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IFN-alpha/▀ R1, Lys28-Lys436, Accession # AAA52730

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human IFN-alpha/▀ R1 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse IFN-alpha/▀ RI is observed.

gene symbol :

IFNAR1

accessionNumbers :

AAA52730

applications :

CyTOF-ready,Flow Cytometry,Western Blot,Neutralization,Immunocytochemistry

USD :

479 USD

alt names :

alpha-type antiviral protein, AVP, beta-type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFNAR, IFN-aR1, IFNAR1, IFNBR, IFNbR1, IFN-bR1, IFN-R-1, interferon (alpha, beta and omega) receptor 1, interferon alpha/beta receptor 1, interferon-alpha/beta receptor alpha chain, interferon-beta receptor 1, Type I interferon receptor 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage