Human Iduronate 2-Sulfatase/IDS Antibody | R&D Systems AF2449 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Iduronate 2-Sulfatase/IDS Antibody

catalog :

AF2449

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 5

Reference
Arguello A, Mahon C, Calvert M, Chan D, Dugas J, Pizzo M, et al. Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme. J Exp Med. 2022;219: pubmed publisher
Hong J, Cheng Y, Yang S, Swaroop M, Xu M, Beers J, et al. iPS-derived neural stem cells for disease modeling and evaluation of therapeutics for mucopolysaccharidosis type II. Exp Cell Res. 2022;412:113007 pubmed publisher
Arguello A, Meisner R, Thomsen E, Nguyen H, Ravi R, Simms J, et al. Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome. JCI Insight. 2021;6: pubmed publisher
Laoharawee K, DeKelver R, Podetz Pedersen K, Rohde M, Sproul S, Nguyen H, et al. Dose-Dependent Prevention of Metabolic and Neurologic Disease in Murine MPS II by ZFN-Mediated In Vivo Genome Editing. Mol Ther. 2018;26:1127-1136 pubmed publisher
Kondo Y, Toyoda T, Ito R, Funato M, Hosokawa Y, Matsui S, et al. Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells. Diabetologia. 2017;60:1454-1466 pubmed publisher

product information

master code :

AF2449

SKU :

AF2449

product name :

Human Iduronate 2-Sulfatase/IDS Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Iduronate 2-Sulfatase/IDS Antibody from R&D Systems is a goat polyclonal antibody to Iduronate 2-Sulfatase/IDS. This antibody reacts with human,mouse. The Human Iduronate 2-Sulfatase/IDS Antibody has been validated for the following applications: Western Blot,ELISA Capture,Immunocytochemistry,Immunoprecipitation.

target :

Iduronate 2-Sulfatase/IDS

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IDS, Ser26-Pro550, Accession # P22304

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human IDS in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse IDS is observed.

gene symbol :

IDS

top caption :

Detection of Human Iduronate 2-Sulfatase/IDS antibody by Western Blot.

accessionNumbers :

P22304

applications :

Western Blot,ELISA Capture,Immunocytochemistry,Immunoprecipitation

USD :

519 USD

alt names :

Alpha-L-iduronate sulfate sulfatase, EC 3.1.6.13, iduronate 2-sulfatase, iduronate 2-sulfatase 14 kDa chain, iduronate 2-sulfatase 42 kDa chain, idursulfase, MPS2, S, SIDS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage