Human IGF-II R/IGF2R Antibody | R&D Systems AF2447 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IGF-II R/IGF2R Antibody

catalog :

AF2447

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Yu X, Pandey K, Katzman A, Alberini C. A role for CIM6P/IGF2 receptor in memory consolidation and enhancement. elife. 2020;9: pubmed publisher
Bella P, Farini A, Banfi S, Parolini D, Tonna N, Meregalli M, et al. Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy. EMBO Mol Med. 2020;12:e11019 pubmed publisher
Mariottini C, Munari L, Gunzel E, Seco J, Tzavaras N, Hansen J, et al. Wilm's tumor 1 promotes memory flexibility. Nat Commun. 2019;10:3756 pubmed publisher
Godoy Parejo C, Deng C, Liu W, Chen G. Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells. Stem Cells. 2019;37:1030-1041 pubmed publisher
Atay C, Kwak T, Lavilla Alonso S, Donthireddy L, Richards A, Moberg V, et al. BRAF Targeting Sensitizes Resistant Melanoma to Cytotoxic T Cells. Clin Cancer Res. 2019;25:2783-2794 pubmed publisher
Gerber H, Mosser S, Boury Jamot B, Stumpe M, Piersigilli A, Goepfert C, et al. The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease. Acta Neuropathol Commun. 2019;7:13 pubmed publisher
Martín Montañez E, Millon C, Boraldi F, Garcia Guirado F, Pedraza C, Lara E, et al. IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids. Redox Biol. 2017;13:69-81 pubmed publisher
Ahmed K, Xiang J. mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A. Cell Discov. 2017;3:17011 pubmed publisher

product information

brand :

R&D Systems

master code :

AF2447

SKU :

AF2447

product name :

Human IGF-II R/IGF2R Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human IGF-II R/IGF2R Antibody from R&D Systems is a goat polyclonal antibody to IGF-II R/IGF2R. This antibody reacts with human,mouse,rat. The Human IGF-II R/IGF2R Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization,In vivo assay,Immunocytochemistry,Immunohistochemistry,Blockade of Receptor-ligand Interaction,CyTOF-ready.

target :

IGF-II R/IGF2R

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, Immunohistochemistry 5-15 ug/mL, Blockade of Receptor-ligand Interaction 0.5-2.5 ug/mL, Immunocytochemistry 5-15 ug/mL, CyTOF-ready

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IGF-II R/IGF2R, Ser1510-Phe2108, Accession # P11717

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human IGF-II R/IGF2R in direct ELISAs and Western blots.

gene symbol :

IGF2R

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of IGF-II R/IGF2R antibody in Human Monocytes antibody by Flow Cytometry.

accessionNumbers :

P11717

applications :

Immunohistochemistry,Blockade of Receptor-ligand Interaction,CyTOF-ready,Flow Cytometry,Western Blot,In vivo assay,Neutralization,Immunocytochemistry

USD :

509 USD

alt names :

300 kDa mannose 6-phosphate receptor, cation-independent mannose-6 phosphate receptor, cation-independent mannose-6-phosphate receptor, CD222, CD222 antigen, CI Man-6-P receptor, CIMPR, CI-MPR, IGF2R, IGF-II receptor, IGFIIR, IGF-IIR, insulin-like growth factor 2 receptorM6P/IGF2R, Insulin-like growth factor II receptor, M6P/IGF2 receptor, M6PR, M6P-R, MPR 300, MPR1, MPRI, MPRIM6PR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage