product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human NKX2.5 Antibody
catalog :
AF2444
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, RNA immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 7
Reference
Ng W, Johnston E, Tan J, Bliley J, Feinberg A, Stolz D, et al. Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells. elife. 2022;11: pubmed publisher
Chen W, Pretorius D, Zhou Y, Nakada Y, Yang J, Zhang J. TT-10-loaded nanoparticles promote cardiomyocyte proliferation and cardiac repair in a mouse model of myocardial infarction. JCI Insight. 2021;6: pubmed publisher
Deepe R, Fitzgerald E, Wolters R, Drummond J, Guzman K, Hoff M, et al. The Mesenchymal Cap of the Atrial Septum and Atrial and Atrioventricular Septation. J Cardiovasc Dev Dis. 2020;7: pubmed publisher
Yang T, Huang Z, Li H, Wang L, Chen Y. Conjugated activation of myocardial-specific transcription of Gja5 by a pair of Nkx2-5-Shox2 co-responsive elements. Dev Biol. 2020;465:79-87 pubmed publisher
Atmanli A, Hu D, Deiman F, van de Vrugt A, Cherbonneau F, Black L, et al. Multiplex live single-cell transcriptional analysis demarcates cellular functional heterogeneity. elife. 2019;8: pubmed publisher
Bertero A, Fields P, Smith A, Leonard A, Beussman K, Sniadecki N, et al. Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy. J Cell Biol. 2019;218:2919-2944 pubmed publisher
Lang J, Young R, Ashraf H, Canty J. Inhibiting Extracellular Vesicle Release from Human Cardiosphere Derived Cells with Lentiviral Knockdown of nSMase2 Differentially Effects Proliferation and Apoptosis in Cardiomyocytes, Fibroblasts and Endothelial Cells In Vitro. PLoS ONE. 2016;11:e0165926 pubmed publisher
product information
master code :
AF2444
SKU :
AF2444
product name :
Human NKX2.5 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human NKX2.5 Antibody from R&D Systems is a goat polyclonal antibody to NKX2.5. This antibody reacts with human,mouse. The Human NKX2.5 Antibody has been validated for the following applications: Immunocytochemistry,RNA immunoprecipitation,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Western Blot.
target :
NKX2.5
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human NKX2.5, Gln24-Arg137, Accession # P52952
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human NKX2.5 in direct ELISAs and Western blots.
gene symbol :
NKX2-5
top caption :
Detection of Human NKX2.5 by Western Blot
accessionNumbers :
P52952
applications :
RNA immunoprecipitation,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot
USD :
509 USD
alt names :
cardiac-specific homeo box, Cardiac-specific homeobox, cardiac-specific homeobox 1, CHNG5, CSX1, CSXFLJ97195, FLJ52202, FLJ99536, Homeobox protein CSX, Homeobox protein NK-2 homolog E, homeobox protein Nkx-2.5, NK2 transcription factor related, locus 5 (Drosophila), NKX2.5FLJ97166, NKX2-5, NKX2E, NKX2EFLJ97197, NKX4-1, tinman paralog
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.