Human DDR1 Antibody | R&D Systems AF2396 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human DDR1 Antibody

catalog :

AF2396

quantity :

100 ug (also 25 ug)

price :

529 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:75; loading ...; fig 1a	Madison J, Wilhelm K, Meehan D, Delimont D, Samuelson G, Cosgrove D. Glomerular basement membrane deposition of collagen α1(III) in Alport glomeruli by mesangial filopodia injures podocytes via aberrant signaling through DDR1 and integrin α2β1. J Pathol. 2022;258:26-37 pubmed publisher
	Sun X, Wu B, Chiang H, Deng H, Zhang X, Xiong W, et al. Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion. Nature. 2021;599:673-678 pubmed publisher
	Zhang Y, Zhang Y, Liang H, Zhuo Z, Fan P, Chen Y, et al. Serum N-terminal DDR1: A Novel Diagnostic Marker of Liver Fibrosis Severity. J Clin Transl Hepatol. 2021;9:702-710 pubmed publisher
	Deng J, Kang Y, Cheng C, Li X, Dai B, Katz M, et al. DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis. JCI Insight. 2021;6: pubmed publisher
	Zhong X, Zhang W, Sun T. DDR1 promotes breast tumor growth by suppressing antitumor immunity. Oncol Rep. 2019;42:2844-2854 pubmed publisher
	Chow C, Ebine K, Knab L, Bentrem D, Kumar K, Munshi H. Cancer Cell Invasion in Three-dimensional Collagen Is Regulated Differentially by GÎ±13 Protein and Discoidin Domain Receptor 1-Par3 Protein Signaling. J Biol Chem. 2016;291:1605-18 pubmed publisher

product information

master code :

AF2396

SKU :

AF2396

product name :

Human DDR1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human DDR1 Antibody from R&D Systems is a goat polyclonal antibody to DDR1. This antibody reacts with human,porcine,primate - chlorocebus aethiops (african green monkey). The Human DDR1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,ELISA Capture,Simple Western.

target :

DDR1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human DDR1, Asp21-Thr416, Accession # Q08345

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Porcine,Primate - Chlorocebus aethiops (African Green Monkey)

specificity :

Detects human DDR1 in direct ELISAs and Western blots. In sandwich immunoassays, approximately 5% cross-reactivity with recombinant human DDR2 is observed.

gene symbol :

DDR1

top caption :

Detection of Human DDR1 antibody by Western Blot.

accessionNumbers :

Q08345

applications :

Western Blot,ELISA Capture,Immunohistochemistry,Simple Western

USD :

529 USD

alt names :

CAK, CD167 antigen-like family member A, CD167a, CD167a antigen, DDR, discoidin domain receptor family, member 1, discoidin domain receptor tyrosine kinase 1, Discoidin receptor tyrosine kinase, EC 2.7.10, EC 2.7.10.1, EDDR1, ENTRK4, Epithelial discoidin domain receptor 1, HGK2, MCK10, MCK-10, NTRK4, Protein-tyrosine kinase 3A, PTK3A, PTK3A protein tyrosine kinase 3A, receptor, type 4, RTK6, TRK E, TrkE

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage