product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-36 gamma /IL-1F9 Antibody
catalog :
AF2320
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
citations: 3
Reference
Baker J, Fenwick P, Koss C, Owles H, Elkin S, Fine J, et al. IL-36 receptor agonist and antagonist imbalance drives neutrophilic inflammation in COPD. JCI Insight. 2022;7: pubmed publisher
Murrieta Coxca J, Gutiérrez Samudio R, El Shorafa H, Groten T, Rodríguez Martínez S, Cancino Diaz M, et al. Role of IL-36 Cytokines in the Regulation of Angiogenesis Potential of Trophoblast Cells. Int J Mol Sci. 2020;22: pubmed publisher
Satoh T, Mellett M, Meier Schiesser B, Fenini G, Otsuka A, Beer H, et al. IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes. J Clin Invest. 2019;: pubmed publisher
product information
master code :
AF2320
SKU :
AF2320
product name :
Human IL-36 gamma /IL-1F9 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human IL-36 gamma /IL-1F9 Antibody from R&D Systems is a goat polyclonal antibody to IL-36 gamma/IL-1F9. This antibody reacts with human. The Human IL-36 gamma /IL-1F9 Antibody has been validated for the following applications: Western Blot,ELISA Development,Blockade of Receptor-ligand Interaction.
target :
IL-36 gamma/IL-1F9
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human IL-36 gamma /IL-1F9 (R D Systems, Catalog # 2320-IL), Met1-Asp169, Accession # Q9NZH8
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human IL-36 gamma /IL-1F9 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human (rh) IL-36 alpha is observed, approximately 5% cross-reactivity with rhIL-37 is observed, and less than 1% cross-reactivity with rhIL-1 alpha , rhIL-1▀, rhIL-36Ra, and rhIL-36▀ is observed.
gene symbol :
IL36G
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human IL-36?/IL-1F9 antibody by Western Blot.
accessionNumbers :
Q9NZH8
applications :
ELISA Development,Western Blot,Blockade of Receptor-ligand Interaction
USD :
499 USD
alt names :
IL-1 epsilon, IL-1 H1, IL-1 Related Protein 2, IL-1(EPSILON), IL1E, IL-1-epsilon, IL1F9, IL-1F9, IL1H1, IL-1H1, IL-1-Related Protein 2, IL1RP2, IL-1RP2, IL36 gamma, IL36G, interleukin 1 family, member 9, interleukin 1-related protein 2, Interleukin 36, Gamma, Interleukin-1 epsilon, interleukin-1 family member 9, Interleukin-1 homolog 1, Interleukin-36 Gamma
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.