product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human FGF acidic/FGF1 Antibody
catalog :
AF232
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, neutralization, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 6
Reference
Liu J, Zhang F, He J, Wang S, Wang L, Li J, et al. Tumor-derived Immunoglobulin-like transcript 4 facilitates angiogenesis of colorectal cancer. Am J Cancer Res. 2023;13:419-435 pubmed
Nicholson H, Sawers L, Clarke R, Hiom K, Ferguson M, Smith G. Fibroblast growth factor signalling influences homologous recombination-mediated DNA damage repair to promote drug resistance in ovarian cancer. Br J Cancer. 2022;127:1340-1351 pubmed publisher
Lampart A, Sluzalska K, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, et al. Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells. Cells. 2022;11: pubmed publisher
Hu H, Piotrowska Z, Hare P, Chen H, Mulvey H, Mayfield A, et al. Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms. Cancer Cell. 2021;39:1531-1547.e10 pubmed publisher
Bhattacharyya S, Oon C, Kothari A, Horton W, Link J, Sears R, et al. Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer. J Exp Med. 2020;217: pubmed publisher
Lakk M, Denes V, Kovacs K, Hideg O, Szabo B, Gabriel R. Pituitary Adenylate Cyclase-Activating Peptide (PACAP), a Novel Secretagogue, Regulates Secreted Morphogens in Newborn Rat Retina. Invest Ophthalmol Vis Sci. 2017;58:565-572 pubmed publisher
product information
brand :
R&D Systems
master code :
AF232
SKU :
AF232
product name :
Human FGF acidic/FGF1 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human FGF acidic/FGF1 Antibody from R&D Systems is a goat polyclonal antibody to FGF acidic/FGF1. This antibody reacts with human,mouse,rat. The Human FGF acidic/FGF1 Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry,Simple Western.
target :
FGF acidic/FGF1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.25 ug/mL, Simple Western 2.5 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization
host :
Goat
immunogen :
E. coli -derived recombinant human FGF acidic/FGF1, Phe16-Asp155, Accession # P05230
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human FGF acidic/FGF1 in direct ELISAs and Western blots. In direct ELISAs, approximately 100% cross-reactivity with recombinant mouse FGF acidic/FGF1 is observed. Neutralizes the biological activity of rhFGF acidic/FGF1. It will also neutralize the biological activity of rh▀-ECGF and bovine FGF acidic/FGF1, although 2-3 times the amount of IgG is required to neutralize bovine FGF acidic/FGF1 biological activity.
gene symbol :
FGF1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human FGF acidic/FGF1 antibody by Western Blot.
accessionNumbers :
P05230
applications :
Immunohistochemistry,Simple Western,Western Blot,Immunohistochemistry-Paraffin,Neutralization
USD :
489 USD
alt names :
AFGF, alpha, alpha-ECGF, beta-ECGF, ECGF, ECGFB, ECGF-betaAcidic fibroblast growth factor, endothelial cell growth factor, beta, FGF acidic, FGF-1, FGFABeta-endothelial cell growth factor, FGF-alpha, fibroblast growth factor 1 (acidic), GLIO703, HBGF1, HBGF-1, heparin-binding growth factor 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.