Mouse IL-36 alpha /IL-1F6 Antibody | R&D Systems AF2297 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-36 alpha /IL-1F6 Antibody

catalog :

AF2297

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Pelcastre Rodriguez C, Vázquez Sánchez E, Murrieta Coxca J, Rodr xed guez Mart xed nez S, Cancino Diaz J, Cancino Diaz M. MES SV40 Cells Are Sensitive to Lipopolysaccharide, Peptidoglycan, and Poly I:C Expressing IL-36 Cytokines. Int J Mol Sci. 2022;23: pubmed publisher
WILLIAMS D, Kim R. Epithelial cells release IL-36α in extracellular vesicles following mechanical damage. Biochem Biophys Res Commun. 2022;605:56-62 pubmed publisher
El Awaisi J, Kavanagh D, Rink M, Weston C, Drury N, Kalia N. Targeting IL-36 improves age-related coronary microcirculatory dysfunction and attenuates myocardial ischemia/reperfusion injury in mice. JCI Insight. 2022;7: pubmed publisher
Wang X, Liang Y, Wang H, Zhang B, Soong L, Cai J, et al. The Protective Role of IL-36/IL-36R Signal in Con A-Induced Acute Hepatitis. J Immunol. 2022;208:861-869 pubmed publisher
Nerlich A, Janze N, Goethe R. Analysis of Il36a induction by C/EBPβ via a half-CRE•C/EBP element in murine macrophages in dependence of its CpG methylation level. Genes Immun. 2021;22:313-321 pubmed publisher
Germán B, Wei R, Hener P, Martins C, Ye T, Gottwick C, et al. Disrupting the IL-36 and IL-23/IL-17 loop underlies the efficacy of calcipotriol and corticosteroid therapy for psoriasis. JCI Insight. 2019;4: pubmed publisher
Masum M, Ichii O, Elewa Y, Nakamura T, Kon Y. Local CD34-positive capillaries decrease in mouse models of kidney disease associating with the severity of glomerular and tubulointerstitial lesions. BMC Nephrol. 2017;18:280 pubmed publisher
Schmitt V, Hahn M, KÃ¤stele V, Wagner O, Wiendl M, Derer A, et al. Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts. Eur J Immunol. 2017;47:2101-2112 pubmed publisher

product information

master code :

AF2297

SKU :

AF2297

product name :

Mouse IL-36 alpha /IL-1F6 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse IL-36 alpha /IL-1F6 Antibody from R&D Systems is a goat polyclonal antibody to IL-36 alpha/IL-1F6. This antibody reacts with mouse. The Mouse IL-36 alpha /IL-1F6 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,ELISA,Blockade of Receptor-ligand Interaction.

target :

IL-36 alpha/IL-1F6

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse IL-36 alpha /IL-1F6, Met1-His160, Accession # Q9JLA2

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse

specificity :

Detects mouse IL-36 alpha /IL-1F6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human (rh) IL-1F5, rhIL-1F6, and rhIL-1F9 is observed, and less than 2% cross-reactivity with recombinant mouse IL-1F8, rhIL-1F7, rhIL-1 alpha , rhIL-1▀, rhIL-1ra, and rhIL-18 is observed.

gene symbol :

IL36A

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

Q9JLA2

applications :

Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,ELISA,Blockade of Receptor-ligand Interaction

USD :

479 USD

alt names :

FIL1, FIL1 epsilon, FIL1(EPSILON), FIL1E, IL-1 epsilon, IL1(EPSILON), IL1E, IL-1E, IL1F6, IL-1F6, IL-1F6 (FIL-1-epsilon), IL36 alpha, IL36A, interleukin 1 family, member 6 (epsilon), interleukin 1, epsilon, Interleukin 36, Alpha, Interleukin-1 epsilon, interleukin-1 family member 6, Interleukin-36 Alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage