product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Phospho-Histone H2AX (S139) Antibody
catalog :
AF2288
quantity :
50 ug (also 25 ug)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
R&D Systems product webpage
citations: 12
Reference
Nataliya B, Mikhail A, Vladimir P, Olga G, Maksim V, Ivan Z, et al. Mesenchymal stromal cells facilitate resolution of pulmonary fibrosis by miR-29c and miR-129 intercellular transfer. Exp Mol Med. 2023;55:1399-1412 pubmed publisher
Zhang D, Navara R, Yin T, SZYMANSKI J, Goldsztejn U, Kenkel C, et al. Cardiac radiotherapy induces electrical conduction reprogramming in the absence of transmural fibrosis. Nat Commun. 2021;12:5558 pubmed publisher
Al Mugotir M, Lovelace J, George J, Bessho M, Pal D, Struble L, et al. Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction. PLoS ONE. 2021;16:e0248941 pubmed publisher
Magalhaes Y, Silva G, Osaki J, Rocha C, Forti F. RHOAming Through the Nucleotide Excision Repair Pathway as a Mechanism of Cellular Response Against the Effects of UV Radiation. Front Cell Dev Biol. 2020;8:816 pubmed publisher
Schepsky A, Traustadóttir G, Joelsson J, Ingthorsson S, Kricker J, Bergthorsson J, et al. Melflufen, a peptide-conjugated alkylator, is an efficient anti-neo-plastic drug in breast cancer cell lines. Cancer Med. 2020;: pubmed publisher
Hellweg C, Shinde V, Srinivasan S, Henry M, Rotshteyn T, Baumstark Khan C, et al. Radiation Response of Murine Embryonic Stem Cells. Cells. 2020;9: pubmed publisher
Miranda S, Correia M, Dias A, Pestana A, Soares P, Nunes J, et al. Evaluation of the role of mitochondria in the non-targeted effects of ionizing radiation using cybrid cellular models. Sci Rep. 2020;10:6131 pubmed publisher
Li H, Wang C, Fu J, Yang X, Sun Y, Shao Y, et al. PTEN expression in U251 glioma cells enhances their sensitivity to ionizing radiation by suppressing DNA repair capacity. Eur Rev Med Pharmacol Sci. 2019;23:10453-10458 pubmed publisher
Wang Y, Bernhardy A, Nacson J, Krais J, Tan Y, Nicolas E, et al. BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance. Nat Commun. 2019;10:5661 pubmed publisher
Simandi Z, Pajer K, Károlyi K, Sieler T, Jiang L, Kolostyak Z, et al. Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons. J Neurosci. 2018;38:7683-7700 pubmed publisher
Jangi M, Fleet C, Cullen P, Gupta S, Mekhoubad S, Chiao E, et al. SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage. Proc Natl Acad Sci U S A. 2017;114:E2347-E2356 pubmed publisher
Rebolleda N, Losada Fernandez I, Perez Chacon G, Castejon R, Rosado S, Morado M, et al. Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model. PLoS ONE. 2016;11:e0154159 pubmed publisher
product information
brand :
R&D Systems
master code :
AF2288
SKU :
AF2288
product name :
Human Phospho-Histone H2AX (S139) Antibody
unit size :
50 ug (also 25 ug)
seo description :
The Human Phospho-Histone H2AX (S139) Antibody from R&D Systems is a rabbit polyclonal antibody to Histone H2AX. This antibody reacts with goat,human,mouse,rat. The Human Phospho-Histone H2AX (S139) Antibody has been validated for the following applications: Immunocytochemistry,Western Blot,Immunohistochemistry,Simple Western.
target :
Histone H2AX
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Simple Western 5 ug/mL, Immunohistochemistry 5-15 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Rabbit
immunogen :
Phosphopeptide containing human Histone H2AX S139 site
isotype :
IgG
purity :
Antigen and protein A Affinity-purified
species :
Goat,Human,Mouse,Rat
specificity :
Detects human Histone H2AX when phosphorylated at S139.
gene symbol :
H2AFX
top caption :
Histone H2AX antibody in Human Breast Cancer Tissue by Immunohistochemistry (IHC-P).
applications :
Simple Western,Immunohistochemistry,Western Blot,Immunocytochemistry
USD :
409 USD
alt names :
H2A.X, H2A/X, H2AFX
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.