Human EPCR Antibody | R&D Systems AF2245 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human EPCR Antibody

catalog :

AF2245

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, dot blot

more info or order :

R&D Systems product webpage

citations: 7

Reference
Di Pietro L, Giacalone F, Ragozzino E, Saccone V, Tiberio F, De Bardi M, et al. Non-myogenic mesenchymal cells contribute to muscle degeneration in facioscapulohumeral muscular dystrophy patients. Cell Death Dis. 2022;13:793 pubmed publisher
Bochenek M, Gogiraju R, Gro xdf mann S, Krug J, Orth J, Reyda S, et al. EPCR-PAR1 biased signaling regulates perfusion recovery and neovascularization in peripheral ischemia. JCI Insight. 2022;7: pubmed publisher
Basu S, Liang H, Hernandez I, Zogg M, Fields B, May J, et al. Role of thrombomodulin expression on hematopoietic stem cells. J Thromb Haemost. 2020;18:123-135 pubmed publisher
Avril M, Benjamin M, Dols M, Smith J. Interplay of Plasmodium falciparum and thrombin in brain endothelial barrier disruption. Sci Rep. 2019;9:13142 pubmed publisher
Ecklu Mensah G, Olsen R, Bengtsson A, Ofori M, Hviid L, Jensen A, et al. Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes. PLoS ONE. 2018;13:e0204177 pubmed publisher
Azasi Y, Lindergard G, Ghumra A, Mu J, Miller L, Rowe J. Infected erythrocytes expressing DC13 PfEMP1 differ from recombinant proteins in EPCR-binding function. Proc Natl Acad Sci U S A. 2018;115:1063-1068 pubmed publisher
Avril M, Bernabeu M, Benjamin M, Brazier A, Smith J. Interaction between Endothelial Protein C Receptor and Intercellular Adhesion Molecule 1 to Mediate Binding of Plasmodium falciparum-Infected Erythrocytes to Endothelial Cells. MBio. 2016;7: pubmed publisher

product information

brand :

R&D Systems

master code :

AF2245

SKU :

AF2245

product name :

Human EPCR Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human EPCR Antibody from R&D Systems is a goat polyclonal antibody to EPCR. This antibody reacts with human,mouse. The Human EPCR Antibody has been validated for the following applications: Immunocytochemistry,Binding Assay,ELISA Development,Flow Cytometry,Western Blot,Dot Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready.

target :

EPCR

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.25 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 1-15 ug/mL, CyTOF-ready

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human EPCR, Ser18-Ser210, Accession # Q9UNN8

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human EPCR in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant mouse EPCR is observed.

gene symbol :

PROCR

top caption :

Detection of Human EPCR antibody by Western Blot.

accessionNumbers :

Q9UNN8

applications :

CyTOF-ready,Binding Assay,ELISA Development,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Dot Blot,Immunocytochemistry

USD :

479 USD

alt names :

APC receptor, CCCA, CCD41, CCD41centrosome-associated protein, CD201, CD201 antigen, centrocyclin, Endothelial cell protein C receptor, endothelial protein C receptor, EPCRMGC23024, PROCR, protein C receptor, endothelial

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage