product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat Neuropilin-2 Antibody
catalog :
AF2215
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 25
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3e
Aoki M, Gamayun I, Wyatt A, Grünewald R, Simon Thomas M, Philipp S, et al. Prolactin-sensitive olfactory sensory neurons regulate male preference in female mice by modulating responses to chemosensory cues. Sci Adv. 2021;7:eabg4074 pubmed publisher
Hung Y, Hou Y, Hsu S, Wang L, Tsai Y, Shan Y, et al. Pancreatic cancer cell-derived semaphorin 3A promotes neuron recruitment to accelerate tumor growth and dissemination. Am J Cancer Res. 2023;13:3417-3432 pubmed
Meier A, Zawada D, De Angelis M, Martens L, Santamaria G, Zengerle S, et al. Epicardioid single-cell genomics uncovers principles of human epicardium biology in heart development and disease. Nat Biotechnol. 2023;: pubmed publisher
Martins L, Brambilla I, Motta A, de Pretis S, Bhat G, Badaloni A, et al. Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity. Neuron. 2022;110:4090-4107.e11 pubmed publisher
Stogsdill J, Kim K, Binan L, Farhi S, Levin J, Arlotta P. Pyramidal neuron subtype diversity governs microglia states in the neocortex. Nature. 2022;608:750-756 pubmed publisher
Islam R, Mishra J, Polavaram N, Bhattacharya S, Hong Z, Bodas S, et al. Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance. Cell Rep. 2022;40:111097 pubmed publisher
Aigrot M, Barthelemy C, Moyon S, Dufayet Chaffaud G, Izagirre Urizar L, Gillet Legrand B, et al. Genetically modified macrophages accelerate myelin repair. EMBO Mol Med. 2022;14:e14759 pubmed publisher
Dutta S, Polavaram N, Islam R, Bhattacharya S, Bodas S, Mayr T, et al. Neuropilin-2 regulates androgen-receptor transcriptional activity in advanced prostate cancer. Oncogene. 2022;41:3747-3760 pubmed publisher
Kschonsak M, Johnson M, Schelling R, Green E, Rouge L, Ho H, et al. Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv. 2022;8:eabm2536 pubmed publisher
Dallinga M, Habani Y, Schimmel A, Dallinga Thie G, Van Noorden C, Klaassen I, et al. The Role of Heparan Sulfate and Neuropilin 2 in VEGFA Signaling in Human Endothelial Tip Cells and Non-Tip Cells during Angiogenesis In Vitro. Cells. 2021;10: pubmed publisher
Bernatz S, Monden D, Gessler F, Radic T, Hattingen E, Senft C, et al. Influence of VEGF-A, VEGFR-1-3, and neuropilin 1-2 on progression-free: and overall survival in WHO grade II and III meningioma patients. J Mol Histol. 2021;52:233-243 pubmed publisher
Limoni G, Murthy S, Jabaudon D, Dayer A, Niquille M. PlexinA4-Semaphorin3A-mediated crosstalk between main cortical interneuron classes is required for superficial interneuron lamination. Cell Rep. 2021;34:108644 pubmed publisher
Dumond A, Brachet E, Durivault J, Vial V, Puszko A, Lepelletier Y, et al. Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma. J Exp Clin Cancer Res. 2021;40:33 pubmed publisher
Do Y, Cho J, Park J, Oh S, Park D, Yoo K, et al. MiR-146a Regulates Migration and Invasion by Targeting NRP2 in Circulating-Tumor Cell Mimicking Suspension Cells. Genes (Basel). 2020;12: pubmed publisher
Apóstolo N, Smukowski S, Vanderlinden J, Condomitti G, Rybakin V, Ten Bos J, et al. Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer. Nat Commun. 2020;11:5171 pubmed publisher
Dimou A, Nasarre C, Peterson Y, Pagano R, Gooz M, Nasarre P, et al. Neuropilin-2b facilitates resistance to tyrosine kinase inhibitors in non-small cell lung cancer. J Thorac Cardiovasc Surg. 2020;: pubmed publisher
Betterman K, Sutton D, Secker G, Kazenwadel J, Oszmiana A, Lim L, et al. Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow. J Clin Invest. 2020;130:3315-3328 pubmed publisher
Lund C, Yellapragada V, Vuoristo S, Balboa D, Trova S, Allet C, et al. Characterization of the human GnRH neuron developmental transcriptome using a GNRH1-TdTomato reporter line in human pluripotent stem cells. Dis Model Mech. 2020;13: pubmed publisher
Malone S, Papadakis G, Messina A, Mimouni N, Trova S, Imbernon M, et al. Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism. elife. 2019;8: pubmed publisher
Martinez Martin N, Marcandalli J, Huang C, Arthur C, Perotti M, Foglierini M, et al. An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor. Cell. 2018;174:1158-1171.e19 pubmed publisher
Raaben M, Jae L, Herbert A, Kuehne A, Stubbs S, Chou Y, et al. NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry. Cell Host Microbe. 2017;22:688-696.e5 pubmed publisher
Volk Draper L, Hall K, Wilber A, Ran S. Lymphatic endothelial progenitors originate from plastic myeloid cells activated by toll-like receptor-4. PLoS ONE. 2017;12:e0179257 pubmed publisher
Tu D, Chang W, Jan M, Tu C, Lu Y, Tai C. Promotion of metastasis of thyroid cancer cells via NRP-2-mediated induction. Oncol Lett. 2016;12:4224-4230 pubmed
Curreli S, Wong B, Latinovic O, Konstantopoulos K, Stamatos N. Class 3 semaphorins induce F-actin reorganization in human dendritic cells: Role in cell migration. J Leukoc Biol. 2016;100:1323-1334 pubmed
Dutta S, Roy S, Polavaram N, Stanton M, Zhang H, Bhola T, et al. Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology. Cancer Res. 2016;76:418-28 pubmed publisher
product information
brand :
R&D Systems
master code :
AF2215
SKU :
AF2215
product name :
Human/Mouse/Rat Neuropilin-2 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat Neuropilin-2 Antibody from R&D Systems is a goat polyclonal antibody to Neuropilin-2. This antibody reacts with human,mouse,rat,transgenic mouse. The Human/Mouse/Rat Neuropilin-2 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Blocking,ELISA Development,Western Blot,Neutralization,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western,Blockade of Receptor-ligand Interaction,CyTOF-ready.
target :
Neuropilin-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Simple Western 10 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 5-15 ug/mL, Blockade of Receptor-ligand Interaction, CyTOF-ready
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Neuropilin-2, Gln23-Tyr855, Accession # Q7LBX6
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse
specificity :
Detects human, mouse, and rat Neuropilin-2 in Western blots.
gene symbol :
NRP2
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human Neuropilin-2 antibody by Western Blot.
accessionNumbers :
Q7LBX6
applications :
Simple Western,Blockade of Receptor-ligand Interaction,CyTOF-ready,Blocking,ELISA Development,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry
USD :
499 USD
alt names :
MGC126574, neuropilin 2, neuropilin-2, Neuropilin2, neuropilin-2a(22), neuropilin-2b(0), NP2, NPN 2, NPN2, PRO2714, receptor for VEGF165 and semaphorins class3, Vascular endothelial cell growth factor 165 receptor 2, vascular endothelial growth factor-165 receptor 2, VEGF1265R2, VEGF165R2neuropilin-2a(17)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.