Human/Mouse STAT5a/b Pan Specific Antibody | R&D Systems AF2168 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse STAT5a/b Pan Specific Antibody

catalog :

AF2168

quantity :

100 ug (also 25 ug)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, neutralization, flow cytometry, chromatin immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 17

Reference
Li H, Chumroenphat T, Boonarsa P, Yahuafai J, Wrigley C, Siriamornpun S. Evaluation of Roasting and Grilling Effects on Chemical Composition, Volatile Profiles, and Toxicity of Stink Bugs (Tessaratoma papillosa): Implications for Utilization as Functional Food Ingredients. Foods. 2023;12: pubmed publisher
Basu R, Brody R, Sandbhor U, Kulkarni P, Davis E, Swegan D, et al. Structure and function of a dual antagonist of the human growth hormone and prolactin receptors with site-specific PEG conjugates. J Biol Chem. 2023;299:105030 pubmed publisher
Read K, Jones D, Pokhrel S, Hales E, Varkey A, Tuazon J, et al. Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity. Nat Commun. 2023;14:1652 pubmed publisher
Pham D, Silberger D, Nguyen K, Gao M, Weaver C, Hatton R. Batf stabilizes Th17 cell development via impaired Stat5 recruitment of Ets1-Runx1 complexes. EMBO J. 2023;42:e109803 pubmed publisher
Al Rawashde F, Al Wajeeh A, Vishkaei M, Saad H, Johan M, Taib W, et al. Thymoquinone Inhibits JAK/STAT and PI3K/Akt/ mTOR Signaling Pathways in MV4-11 and K562 Myeloid Leukemia Cells. Pharmaceuticals (Basel). 2022;15: pubmed publisher
Al Rawashde F, Wan Taib W, Ismail I, Johan M, Al Wajeeh A, Al Jamal H. Thymoquinone Induces Downregulation of BCR-ABL/JAK/STAT Pathway and Apoptosis in K562 Leukemia Cells. Asian Pac J Cancer Prev. 2021;22:3959-3965 pubmed publisher
Lin A, Elbezanti W, Schirling A, Ahmed A, Van Duyne R, Cocklin S, et al. Alprazolam Prompts HIV-1 Transcriptional Reactivation and Enhances CTL Response Through RUNX1 Inhibition and STAT5 Activation. Front Neurol. 2021;12:663793 pubmed publisher
Yue X, Samaniego Castruita D, Gonz xe1 lez Avalos E, Li X, Barwick B, Rao A. Whole-genome analysis of TET dioxygenase function in regulatory T cells. EMBO Rep. 2021;22:e52716 pubmed publisher
Wiedemann G, Santosa E, Grassmann S, Sheppard S, Le Luduec J, Adams N, et al. Deconvoluting global cytokine signaling networks in natural killer cells. Nat Immunol. 2021;22:627-638 pubmed publisher
Schoepf A, Salcher S, Obexer P, Gust R. Tackling resistance in chronic myeloid leukemia: Novel cell death modulators with improved efficacy. Eur J Med Chem. 2021;216:113285 pubmed publisher
Wiedemann G, Grassmann S, Lau C, Rapp M, Villarino A, Friedrich C, et al. Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells. Cell Rep. 2020;33:108498 pubmed publisher
Heizmann B, Le Gras S, Simand C, Marchal P, Chan S, Kastner P. Ikaros antagonizes DNA binding by STAT5 in pre-B cells. PLoS ONE. 2020;15:e0242211 pubmed publisher
Xiao Y, Qureischi M, Dietz L, Vaeth M, Vallabhapurapu S, Klein Hessling S, et al. Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity. J Exp Med. 2021;218: pubmed publisher
Elbezanti W, Lin A, Schirling A, Jackson A, Marshall M, Duyne R, et al. Benzodiazepines Drive Alteration of Chromatin at the Integrated HIV-1 LTR. Viruses. 2020;12: pubmed publisher
Yip S, Romano N, Gustafson P, Hodson D, Williams E, Kokay I, et al. Elevated Prolactin during Pregnancy Drives a Phenotypic Switch in Mouse Hypothalamic Dopaminergic Neurons. Cell Rep. 2019;26:1787-1799.e5 pubmed publisher
Ganaie S, Zou W, Xu P, Deng X, Kleiboeker S, Qiu J. Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex. PLoS Pathog. 2017;13:e1006370 pubmed publisher
Mokada Gopal L, Boeser A, Lehmann C, Drepper F, Dudziak D, Warscheid B, et al. Identification of Novel STAT6-Regulated Proteins in Mouse B Cells by Comparative Transcriptome and Proteome Analysis. J Immunol. 2017;198:3737-3745 pubmed publisher

product information

brand :

R&D Systems

master code :

AF2168

SKU :

AF2168

product name :

Human/Mouse STAT5a/b Pan Specific Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse STAT5a/b Pan Specific Antibody from R&D Systems is a rabbit polyclonal antibody to STAT5a/b. This antibody reacts with human,mouse. The Human/Mouse STAT5a/b Pan Specific Antibody has been validated for the following applications: Simple Western,Flow Cytometry,Western Blot,Neutralization,Functional Assay,Chromatin Immunoprecipitation (ChIP).

target :

STAT5a/b

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Simple Western 20 ug/mL, Chromatin Immunoprecipitation (ChIP) 5 ug/5 x 10^6 cells

host :

Rabbit

immunogen :

Human STAT5a and STAT5b synthetic peptide, aa 219-390

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects endogenous human and mouse STAT5A and STAT5B in Western blots.

gene symbol :

STAT5A

top caption :

Detection of Human/Mouse STAT5a/b antibody by Western Blot.

applications :

Flow Cytometry,Western Blot,Simple Western,Neutralization,Chromatin Immunoprecipitation (ChIP),Functional Assay

USD :

409 USD

alt names :

MGF, STAT5, STAT5A signal transducer and activator of transcription 5A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage