product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human M-CSF Antibody
catalog :
AF216
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry, neutralization, blocking or activating experiments
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; human; 2 ug/ml; fig 6g
  • western blot; human; loading ...; fig 6f, s6i
Zhang J, Zhang H, Ding X, Hu J, Li Y, Zhang J, et al. Crosstalk between macrophage-derived PGE2 and tumor UHRF1 drives hepatocellular carcinoma progression. Theranostics. 2022;12:3776-3793 pubmed publisher
Li Y, Chen C, Liu H, Zhang Z, Wang C. LARRPM restricts lung adenocarcinoma progression and M2 macrophage polarization through epigenetically regulating LINC00240 and CSF1. Cell Mol Biol Lett. 2022;27:91 pubmed publisher
Pu J, Li W, Wang A, Zhang Y, Qin Z, Xu Z, et al. Long non-coding RNA HOMER3-AS1 drives hepatocellular carcinoma progression via modulating the behaviors of both tumor cells and macrophages. Cell Death Dis. 2021;12:1103 pubmed publisher
Zhang J, Li H, Wu Q, Chen Y, Deng Y, Yang Z, et al. Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth. Redox Biol. 2019;22:101116 pubmed publisher
product information
master code :
AF216
SKU :
AF216
product name :
Human M-CSF Antibody
unit size :
100 ug (also 25 ug)
description :
The Human M-CSF Antibody from R&D Systems is a goat polyclonal antibody to M-CSF. This antibody reacts with human. The Human M-CSF Antibody has been validated for the following applications: Neutralization,Western Blot,Cell Culture,Immunocytochemistry.
target :
M-CSF
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human M-CSF, Glu33-Ser190, Accession # NP_757350
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human M-CSF in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse (rm) M-CSF is observed, and less than 1% cross-reactivity with recombinant rat M-CSF, rmSCF, and recombinant human SCF is observed.
gene symbol :
CSF1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by M-CSF and Neutralization by Human M-CSF Antibody.
accessionNumbers :
NP_757350
applications :
Neutralization,Western Blot,Cell Culture,Immunocytochemistry
USD :
499 USD
alt names :
colony stimulating factor 1 (macrophage), CSF1, CSF-1, Lanimostim, macrophage colony stimulating factor, macrophage colony-stimulating factor 1, MCSF, M-CSF, MCSFlanimostim, MGC31930
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.