product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse B7-H4 Antibody
catalog :
AF2154
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 3
Reference
Castro Pando S, Howell R, Li L, Mascaró M, Faraoni E, Le Roux O, et al. Pancreatic Epithelial IL17/IL17RA Signaling Drives B7-H4 Expression to Promote Tumorigenesis. Cancer Immunol Res. 2024;12:1170-1183 pubmed publisher
MacGregor H, Ohashi P. Molecular Pathways: Evaluating the Potential for B7-H4 as an Immunoregulatory Target. Clin Cancer Res. 2017;23:2934-2941 pubmed publisher
Radichev I, Maneva Radicheva L, Amatya C, Salehi M, Parker C, Ellefson J, et al. Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes. J Immunol. 2016;196:1495-506 pubmed publisher
product information
master code :
AF2154
SKU :
AF2154
product name :
Human/Mouse B7-H4 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse B7-H4 Antibody from R&D Systems is a goat polyclonal antibody to B7-H4. This antibody reacts with human,mouse,transgenic mouse. The Human/Mouse B7-H4 Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Western Blot,CyTOF-ready.
target :
B7-H4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse B7-H4, Phe29-Pro258, Accession # Q7TSP5
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects mouse B7-H4 in direct ELISAs and Western blots. Detects human and mouse B7-H4 in Western blots.
gene symbol :
VTCN1
top caption :
Detection of Mouse and Human B7-H4 antibody by Western Blot.
accessionNumbers :
Q7TSP5
applications :
Immunohistochemistry,Flow Cytometry,Western Blot,CyTOF-ready
USD :
489 USD
alt names :
B7h.5, B7H4, B7-H4, B7H4T-cell costimulatory molecule B7x, B7S1, B7S1VCTN1, B7x, B7XPRO1291, FLJ22418, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, V-set domain containing T cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.