This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Mouse LYVE-1 Antibody
catalog :
AF2125-SP
quantity :
25 ug
price :
135 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry
citations: 30
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1b
Tai Nagara I, Hasumi Y, Kusumoto D, Hasumi H, Okabe K, Ando T, et al. Blood and lymphatic systems are segregated by the FLCN tumor suppressor. Nat Commun. 2020;11:6314 pubmed publisher
Sibler E, He Y, Ducoli L, Keller N, Fujimoto N, Dieterich L, et al. Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes. Cells. 2021;10: pubmed publisher
Inomata T, Fujimoto K, Okumura Y, Zhu J, Fujio K, Shokirova H, et al. Novel immunotherapeutic effects of topically administered ripasudil (K-115) on corneal allograft survival. Sci Rep. 2020;10:19817 pubmed publisher
Subileau M, Acar N, Carret A, Bretillon L, Vilgrain I, Bailly S, et al. Eye lymphatic defects induced by bone morphogenetic protein 9 deficiency have no functional consequences on intraocular pressure. Sci Rep. 2020;10:16040 pubmed publisher
Sogawa Fujiwara C, Hanagata A, Fujiwara Y, Ishida Y, Tomiyasu H, Kunieda T, et al. Defective development and microcirculation of intestine in Npr2 mutant mice. Sci Rep. 2020;10:14761 pubmed publisher
Honda M, Ito Y, Hattori K, Hosono K, Sekiguchi K, Tsujikawa K, et al. Inhibition of receptor activity-modifying protein 1 suppresses the development of endometriosis and the formation of blood and lymphatic vessels. J Cell Mol Med. 2020;24:11984-11997 pubmed publisher
Chakraborty A, Scogin C, Rizwan K, Morley T, Rutkowski J. Characterizing Lymphangiogenesis and Concurrent Inflammation in Adipose Tissue in Response to VEGF-D. Front Physiol. 2020;11:363 pubmed publisher
Park C, Lin P, Zhou S, Barakat R, Bashir S, Choi J, et al. Progesterone Receptor Serves the Ovary as a Trigger of Ovulation and a Terminator of Inflammation. Cell Rep. 2020;31:107496 pubmed publisher
Song E, Mao T, Dong H, Boisserand L, Antila S, Bosenberg M, et al. VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours. Nature. 2020;577:689-694 pubmed publisher
Zhu G, Du Q, Chen X, Wang X, Tang N, She F, et al. Receptor‑interacting serine/threonine‑protein kinase 1 promotes the progress and lymph metastasis of gallbladder cancer. Oncol Rep. 2019;42:2435-2449 pubmed publisher
Yoon S, Dieterich L, Karaman S, Proulx S, Bachmann S, Sciaroni C, et al. An important role of cutaneous lymphatic vessels in coordinating and promoting anagen hair follicle growth. PLoS ONE. 2019;14:e0220341 pubmed publisher
Esterházy D, Canesso M, Mesin L, Muller P, de Castro T, Lockhart A, et al. Compartmentalized gut lymph node drainage dictates adaptive immune responses. Nature. 2019;569:126-130 pubmed publisher
Reed H, Wang L, Sonett J, Chen M, Yang J, Li L, et al. Lymphatic impairment leads to pulmonary tertiary lymphoid organ formation and alveolar damage. J Clin Invest. 2019;129:2514-2526 pubmed publisher
Dili A, Lebrun V, Bertrand C, Leclercq I. Associating liver partition and portal vein ligation for staged hepatectomy: establishment of an animal model with insufficient liver remnant. Lab Invest. 2019;99:698-707 pubmed publisher
Subileau M, Merdzhanova G, Ciais D, Collin Faure V, Feige J, Bailly S, et al. Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation. Stem Cell Reports. 2019;12:98-111 pubmed publisher
Gucciardo E, Loukovaara S, Salven P, Lehti K. Lymphatic Vascular Structures: A New Aspect in Proliferative Diabetic Retinopathy. Int J Mol Sci. 2018;19: pubmed publisher
Durré T, Morfoisse F, Erpicum C, Ebroin M, Blacher S, García Caballero M, et al. uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis. Nat Commun. 2018;9:5178 pubmed publisher
Li C, Jiang X, Lin B, Hong H, Zhu S, Jiang L, et al. RIP1 regulates TNF-α-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-κB-VEGF-C pathway. Onco Targets Ther. 2018;11:2875-2890 pubmed publisher
García Nores G, Ly C, Cuzzone D, Kataru R, Hespe G, Torrisi J, et al. CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema. Nat Commun. 2018;9:1970 pubmed publisher
Hominick D, Silva A, Khurana N, Liu Y, Dechow P, Feng J, et al. VEGF-C promotes the development of lymphatics in bone and bone loss. elife. 2018;7: pubmed publisher
Kontarakis Z, Rossi A, Ramas S, Dellinger M, Stainier D. Mir-126 is a conserved modulator of lymphatic development. Dev Biol. 2018;437:120-130 pubmed publisher
Lam L, Watson A, Ryman K, Klimstra W. Gamma-interferon exerts a critical early restriction on replication and dissemination of yellow fever virus vaccine strain 17D-204. NPJ Vaccines. 2018;3:5 pubmed publisher
Westendorp B, Büller N, Karpus O, van Dop W, Koster J, Versteeg R, et al. Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response. Cell Mol Gastroenterol Hepatol. 2018;5:67-82.e1 pubmed publisher
García Caballero M, Paupert J, Blacher S, Van de Velde M, Quesada A, Medina M, et al. Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases. J Hematol Oncol. 2017;10:122 pubmed publisher
Jiang X, Li C, Lin B, Hong H, Jiang L, Zhu S, et al. cIAP2 promotes gallbladder cancer invasion and lymphangiogenesis by activating the NF-κB pathway. Cancer Sci. 2017;108:1144-1156 pubmed publisher
Cha B, Geng X, Mahamud M, Fu J, Mukherjee A, Kim Y, et al. Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016;30:1454-69 pubmed publisher
Bui H, Enis D, Robciuc M, Nurmi H, Cohen J, Chen M, et al. Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD. J Clin Invest. 2016;126:2167-80 pubmed publisher
Shinoda K, Hirahara K, Iinuma T, Ichikawa T, Suzuki A, Sugaya K, et al. Thy1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation. Proc Natl Acad Sci U S A. 2016;113:E2842-51 pubmed publisher
Crosswhite P, Podsiadlowska J, Curtis C, Gao S, Xia L, Srinivasan R, et al. CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity. J Clin Invest. 2016;126:2254-66 pubmed publisher
Geng X, Cha B, Mahamud M, Lim K, Silasi Mansat R, Uddin M, et al. Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016;409:218-233 pubmed publisher
product information
brand :
R&D Systems
master code :
AF2125
SKU :
AF2125-SP
product name :
Mouse LYVE-1 Antibody
description :
The Mouse LYVE-1 Antibody from R&D Systems is a goat polyclonal antibody to LYVE-1. This antibody reacts with mouse. The Mouse LYVE-1 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry.
target :
LYVE-1
category :
Primary Antibodies
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse LYVE-1, Ala24-Thr234, Accession # Q8BHC0
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse LYVE-1 in direct ELISAs and Western blots.
gene symbol :
LYVE1
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
Q8BHC0
applications :
Western Blot, Immunohistochemistry
USD 2021 :
129
USD 2022 :
135 USD
alt name :
cell surface retention sequence binding protein-1, Cell surface retention sequence-binding protein 1, CRSBP1, CRSBP-1, extracellular link domain containing 1, extracellular link domain-containing 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, lymphatic vessel endothelial hyaluronan receptor 1, lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1, LYVE-1, UNQ230/PRO263, XLKD1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.