product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Smad4 Antibody
catalog :
AF2097
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
more info or order :
citations: 5
Reference
Lin L, Kost E, Lin C, Valente P, Wang C, Kolonin M, et al. PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer. Cell Rep. 2020;33:108253 pubmed publisher
Fang Y, Han X, Li J, Kuang T, Lou W. HEATR1 Deficiency Promotes Chemoresistance via Upregulating ZNF185 and Downregulating SMAD4 in Pancreatic Cancer. J Oncol. 2020;2020:3181596 pubmed publisher
Kumeda N, Ogawa Y, Akimoto Y, Kawakami H, Tsujimoto M, Yanoshita R. Characterization of Membrane Integrity and Morphological Stability of Human Salivary Exosomes. Biol Pharm Bull. 2017;40:1183-1191 pubmed publisher
Moen M, Adams H, Brandsma J, Dekkers D, Akinci U, Karkampouna S, et al. An interaction network of mental disorder proteins in neural stem cells. Transl Psychiatry. 2017;7:e1082 pubmed publisher
de Kroon L, Narcisi R, van den Akker G, Vitters E, Blaney Davidson E, van Osch G, et al. SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells. Sci Rep. 2017;7:43164 pubmed publisher
product information
master code :
AF2097
SKU :
AF2097
product name :
Human Smad4 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Smad4 Antibody from R&D Systems is a goat polyclonal antibody to Smad4. This antibody reacts with human. The Human Smad4 Antibody has been validated for the following applications: Chromatin Immunoprecipitation (ChIP),Immunoprecipitation,Western Blot,Simple Western,Immunocytochemistry.
target :
Smad4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human Smad4, Pro139-Asp332, Accession # Q13485
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human Smad4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 15% cross-reactivity with recombinant human (rh) Smad1 and less than 5% cross-reactivity with rhSmad9, rhSmad5, and rhSmad7 is observed.
gene symbol :
SMAD4
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Human Smad4 antibody by Western Blot.
accessionNumbers :
Q13485
applications :
Chromatin Immunoprecipitation (ChIP),Immunoprecipitation,Western Blot,Simple Western,Immunocytochemistry
USD :
499 USD
alt names :
DPC4, DPC4SMAD, mothers against DPP homolog 4 (Drosophila), hSMAD4, JIP, MAD homolog 4, MADH4, MADH4mothers against decapentaplegic homolog 4, mothers against decapentaplegic homolog 4, mothers against decapentaplegic, Drosophila, homolog of, 4, SMAD 4, SMAD family member 4MAD, mothers against decapentaplegic homolog 4 (Drosophila), SMAD, mothers against DPP homolog 4, Smad4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.