Human LYVE-1 Antibody | R&D Systems AF2089 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human LYVE-1 Antibody

catalog :

AF2089

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 27

Reference
Pavlovic B, Br xe4 utigam K, Dartiguenave F, Martel P, Rakauskas A, Cesson V, et al. Urine biomarkers can predict prostate cancer and PI-RADS score prior to biopsy. Sci Rep. 2024;14:18148 pubmed publisher
Saiki N, Nio Y, Yoneyama Y, Kawamura S, Iwasawa K, Kawakami E, et al. Self-Organization of Sinusoidal Vessels in Pluripotent Stem Cell-derived Human Liver Bud Organoids. bioRxiv. 2024;: pubmed publisher
Fitzpatrick Z, Ghabdan Zanluqui N, Rosenblum J, Tuong Z, Lee C, Chandrashekhar V, et al. Venous-plexus-associated lymphoid hubs support meningeal humoral immunity. Nature. 2024;628:612-619 pubmed publisher
Yoon C, Lu J, Jun Y, Suh Y, Kim B, Till J, et al. KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis. BMC Cancer. 2023;23:690 pubmed publisher
Egozi A, Olaloye O, Werner L, Silva T, McCourt B, Pierce R, et al. Single-cell atlas of the human neonatal small intestine affected by necrotizing enterocolitis. PLoS Biol. 2023;21:e3002124 pubmed publisher
Stock A, Parsons S, Sharma V, James F, Starkey G, D Costa R, et al. Intimal macrophages develop from circulating monocytes during vasculitis. Clin Transl Immunology. 2022;11:e1412 pubmed publisher
Niec R, Chu T, Schernthanner M, Gur Cohen S, Hidalgo L, Pasolli H, et al. Lymphatics act as a signaling hub to regulate intestinal stem cell activity. Cell Stem Cell. 2022;29:1067-1082.e18 pubmed publisher
Mece O, Houbaert D, Sassano M, Durré T, Maes H, Schaaf M, et al. Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis. Nat Commun. 2022;13:2760 pubmed publisher
G xf3 mez Salinero J, Izzo F, Lin Y, Houghton S, Itkin T, Geng F, et al. Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction. Cell Stem Cell. 2022;29:593-609.e7 pubmed publisher
Mehrara B, Park H, Kataru R, Bromberg J, Coriddi M, Baik J, et al. Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema. Biology (Basel). 2021;10: pubmed publisher
Grierson I, Minckler D, Rippy M, Marshall A, Collignon N, Bianco J, et al. A novel suprachoroidal microinvasive glaucoma implant: in vivo biocompatibility and biointegration. BMC Biomed Eng. 2020;2:10 pubmed publisher
Wu Y, Seong Y, Li K, Choi D, Park E, Daghlian G, et al. Organogenesis and distribution of the ocular lymphatic vessels in the anterior eye. JCI Insight. 2020;5: pubmed publisher
van den Bosch Q, Van Beek J, Kilic E, Verdijk R. Transient Expression of Lymphatic Markers in Retrobulbar Intraconal Orbital Vasculature During Fetal Development. Invest Ophthalmol Vis Sci. 2020;61:22 pubmed publisher
Wang Y, Chaffee T, LaRue R, Huggins D, Witschen P, Ibrahim A, et al. Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice. elife. 2020;9: pubmed publisher
Yoshimatsu Y, Kimuro S, Pauty J, Takagaki K, Nomiyama S, Inagawa A, et al. TGF-beta and TNF-alpha cooperatively induce mesenchymal transition of lymphatic endothelial cells via activation of Activin signals. PLoS ONE. 2020;15:e0232356 pubmed publisher
Stanly T, Fritzsche M, Banerji S, Shrestha D, Schneider F, Eggeling C, et al. The cortical actin network regulates avidity-dependent binding of hyaluronan by the lymphatic vessel endothelial receptor LYVE-1. J Biol Chem. 2020;295:5036-5050 pubmed publisher
Li C, Lin Y, Huang T, Pan J, Wang G. Receptor-Interacting Protein Kinase 1 Promotes Cholangiocarcinoma Proliferation And Lymphangiogenesis Through The Activation Protein 1 Pathway. Onco Targets Ther. 2019;12:9029-9040 pubmed publisher
Van Beek J, van den Bosch Q, Naus N, Paridaens D, de Klein A, Kilic E, et al. Absence of Intraocular Lymphatic Vessels in Uveal Melanomas with Extrascleral Growth. Cancers (Basel). 2019;11: pubmed publisher
Sun M, Chan A, Law S, Duarte S, Diaz Aguilar D, Wadehra M, et al. Epithelial Membrane Protein-2 (EMP2) Antibody Blockade Reduces Corneal Neovascularization in an In Vivo Model. Invest Ophthalmol Vis Sci. 2019;60:245-254 pubmed publisher
Ganchua S, Cadena A, Maiello P, Gideon H, Myers A, Junecko B, et al. Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques. PLoS Pathog. 2018;14:e1007337 pubmed publisher
Wen Y, Yang J, Wang X, Yao Z. Induced dural lymphangiogenesis facilities soluble amyloid-beta clearance from brain in a transgenic mouse model of Alzheimer's disease. Neural Regen Res. 2018;13:709-716 pubmed publisher
Yuge R, Kitadai Y, Takigawa H, Naito T, Oue N, Yasui W, et al. Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer. Transl Oncol. 2018;11:575-584 pubmed publisher
Cochain C, Vafadarnejad E, Arampatzi P, Pelisek J, Winkels H, Ley K, et al. Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis. Circ Res. 2018;122:1661-1674 pubmed publisher
Mitrofanova I, Zavyalova M, Riabov V, Cherdyntseva N, Kzhyshkowska J. The effect of neoadjuvant chemotherapy on the correlation of tumor-associated macrophages with CD31 and LYVE-1. Immunobiology. 2018;223:449-459 pubmed publisher
Hägerling R, Drees D, Scherzinger A, Dierkes C, Martin Almedina S, Butz S, et al. VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations. JCI Insight. 2017;2: pubmed publisher
Volk Draper L, Hall K, Wilber A, Ran S. Lymphatic endothelial progenitors originate from plastic myeloid cells activated by toll-like receptor-4. PLoS ONE. 2017;12:e0179257 pubmed publisher
Scherer S, Bauer J, Schmaus A, Neumaier C, Herskind C, Veldwijk M, et al. TGF-β1 Is Present at High Levels in Wound Fluid from Breast Cancer Patients Immediately Post-Surgery, and Is Not Increased by Intraoperative Radiation Therapy (IORT). PLoS ONE. 2016;11:e0162221 pubmed publisher

product information

master code :

AF2089

SKU :

AF2089

product name :

Human LYVE-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human LYVE-1 Antibody from R&D Systems is a goat polyclonal antibody to LYVE-1. This antibody reacts with human,mouse,primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque),primate - macaca mulatta (rhesus macaque),rabbit,xenograft,lambs. The Human LYVE-1 Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Blockade of Receptor-ligand Interaction.

target :

LYVE-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human LYVE-1, Ser24-Thr238, Accession # Q9Y5Y7

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque),Primate - Macaca mulatta (Rhesus Macaque),Rabbit,Xenograft

specificity :

Detects human LYVE-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 35% cross-reactivity with recombinant mouse LYVE-1 and less than 1% cross-reactivity with recombinant human CD44 is observed.

gene symbol :

LYVE1

endotoxin note :

<0.30 EU per 1 ╡g of the antibody by the LAL method.

top caption :

LYVE-1 antibody in Human Tonsil by Immunohistochemistry (IHC-P).

accessionNumbers :

Q9Y5Y7

applications :

Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Blockade of Receptor-ligand Interaction

USD :

509 USD

alt names :

cell surface retention sequence binding protein-1, Cell surface retention sequence-binding protein 1, CRSBP1, CRSBP-1, extracellular link domain containing 1, extracellular link domain-containing 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, lymphatic vessel endothelial hyaluronan receptor 1, lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1, LYVE-1, UNQ230/PRO263, XLKD1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage