Human LYVE-1 Antibody | R&D Systems AF2089-SP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human LYVE-1 Antibody

catalog :

AF2089-SP

quantity :

25 ug

price :

135 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

citations: 13

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:1000; loading ...; fig 1	van den Bosch Q, Van Beek J, Kilic E, Verdijk R. Transient Expression of Lymphatic Markers in Retrobulbar Intraconal Orbital Vasculature During Fetal Development. Invest Ophthalmol Vis Sci. 2020;61:22 pubmed publisher
	Yoshimatsu Y, Kimuro S, Pauty J, Takagaki K, Nomiyama S, Inagawa A, et al. TGF-beta and TNF-alpha cooperatively induce mesenchymal transition of lymphatic endothelial cells via activation of Activin signals. PLoS ONE. 2020;15:e0232356 pubmed publisher
	Stanly T, Fritzsche M, Banerji S, Shrestha D, Schneider F, Eggeling C, et al. The cortical actin network regulates avidity-dependent binding of hyaluronan by the lymphatic vessel endothelial receptor LYVE-1. J Biol Chem. 2020;295:5036-5050 pubmed publisher
	Li C, Lin Y, Huang T, Pan J, Wang G. Receptor-Interacting Protein Kinase 1 Promotes Cholangiocarcinoma Proliferation And Lymphangiogenesis Through The Activation Protein 1 Pathway. Onco Targets Ther. 2019;12:9029-9040 pubmed publisher
	Sun M, Chan A, Law S, Duarte S, Diaz Aguilar D, Wadehra M, et al. Epithelial Membrane Protein-2 (EMP2) Antibody Blockade Reduces Corneal Neovascularization in an In Vivo Model. Invest Ophthalmol Vis Sci. 2019;60:245-254 pubmed publisher
	Ganchua S, Cadena A, Maiello P, Gideon H, Myers A, Junecko B, et al. Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques. PLoS Pathog. 2018;14:e1007337 pubmed publisher
	Wen Y, Yang J, Wang X, Yao Z. Induced dural lymphangiogenesis facilities soluble amyloid-beta clearance from brain in a transgenic mouse model of Alzheimer's disease. Neural Regen Res. 2018;13:709-716 pubmed publisher
	Yuge R, Kitadai Y, Takigawa H, Naito T, Oue N, Yasui W, et al. Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer. Transl Oncol. 2018;11:575-584 pubmed publisher
	Cochain C, Vafadarnejad E, Arampatzi P, Pelisek J, Winkels H, Ley K, et al. Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis. Circ Res. 2018;122:1661-1674 pubmed publisher
	Mitrofanova I, Zavyalova M, Riabov V, Cherdyntseva N, Kzhyshkowska J. The effect of neoadjuvant chemotherapy on the correlation of tumor-associated macrophages with CD31 and LYVE-1. Immunobiology. 2018;223:449-459 pubmed publisher
	Hägerling R, Drees D, Scherzinger A, Dierkes C, Martin Almedina S, Butz S, et al. VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations. JCI Insight. 2017;2: pubmed publisher
	Volk Draper L, Hall K, Wilber A, Ran S. Lymphatic endothelial progenitors originate from plastic myeloid cells activated by toll-like receptor-4. PLoS ONE. 2017;12:e0179257 pubmed publisher
	Scherer S, Bauer J, Schmaus A, Neumaier C, Herskind C, Veldwijk M, et al. TGF-β1 Is Present at High Levels in Wound Fluid from Breast Cancer Patients Immediately Post-Surgery, and Is Not Increased by Intraoperative Radiation Therapy (IORT). PLoS ONE. 2016;11:e0162221 pubmed publisher

product information

brand :

R&D Systems

master code :

AF2089

SKU :

AF2089-SP

product name :

Human LYVE-1 Antibody

description :

The Human LYVE-1 Antibody from R&D Systems is a goat polyclonal antibody to LYVE-1. This antibody reacts with human. The Human LYVE-1 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Blockade of Receptor-ligand Interaction.

target :

LYVE-1

category :

Primary Antibodies

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human LYVE-1, Ser24-Thr238, Accession # Q9Y5Y7

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human

specificity :

Detects human LYVE-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 35% cross-reactivity with recombinant mouse LYVE-1 and less than 1% cross-reactivity with recombinant human CD44 is observed.

gene symbol :

LYVE1

endotoxin note :

<0.30 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

Q9Y5Y7

applications :

Western Blot, Immunohistochemistry, Blockade of Receptor-ligand Interaction

USD 2021 :

129

USD 2022 :

135 USD

alt name :

cell surface retention sequence binding protein-1, Cell surface retention sequence-binding protein 1, CRSBP1, CRSBP-1, extracellular link domain containing 1, extracellular link domain-containing 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, lymphatic vessel endothelial hyaluronan receptor 1, lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1, LYVE-1, UNQ230/PRO263, XLKD1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.