product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Langerin/CD207 Antibody
catalog :
AF2088
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, neutralization, immunohistochemistry - frozen section
more info or order :
citations: 7
Reference
Cohen E, Mariotton J, Rozenberg F, Sams A, van Kuppevelt T, Barry Delongchamps N, et al. CGRP inhibits human Langerhans cells infection with HSV by differentially modulating specific HSV-1 and HSV-2 entry mechanisms. Mucosal Immunol. 2022;15:762-771 pubmed publisher
Bertram K, Truong N, Smith J, Kim M, Sandgren K, Feng K, et al. Herpes Simplex Virus type 1 infects Langerhans cells and the novel epidermal dendritic cell, Epi-cDC2s, via different entry pathways. PLoS Pathog. 2021;17:e1009536 pubmed publisher
Thornton S, Samararatne V, Skeate J, Buser C, Lühen K, Taylor J, et al. The Essential Role of anxA2 in Langerhans Cell Birbeck Granules Formation. Cells. 2020;9: pubmed publisher
Bertram K, Botting R, Baharlou H, Rhodes J, Rana H, Graham J, et al. Identification of HIV transmitting CD11c+ human epidermal dendritic cells. Nat Commun. 2019;10:2759 pubmed publisher
Chiramel A, Meyerson N, McNally K, Broeckel R, Montoya V, Méndez Solís O, et al. TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019;27:3269-3283.e6 pubmed publisher
Yang C, Lin S, Chiang C, Wu Y, H ng W, Chang C, et al. Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans. Am J Hum Genet. 2018;102:219-232 pubmed publisher
Prodger J, Gray R, Shannon B, Shahabi K, Kong X, Grabowski K, et al. Chemokine Levels in the Penile Coronal Sulcus Correlate with HIV-1 Acquisition and Are Reduced by Male Circumcision in Rakai, Uganda. PLoS Pathog. 2016;12:e1006025 pubmed publisher
product information
brand :
R&D Systems
master code :
AF2088
SKU :
AF2088
product name :
Human Langerin/CD207 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Langerin/CD207 Antibody from R&D Systems is a goat polyclonal antibody to Langerin/CD207. This antibody reacts with human. The Human Langerin/CD207 Antibody has been validated for the following applications: Immunohistochemistry,Immunoelectron Microscopy,Western Blot,Neutralization,Immunohistochemistry-Frozen.
target :
Langerin/CD207
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Langerin/CD207, Tyr64-Pro328, Accession # Q9UJ71
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human Langerin/CD207 in direct ELISAs and Western blots.
gene symbol :
CD207
top caption :
Langerin/CD207 antibody in Human Skin by Immunohistochemistry (IHC-P).
accessionNumbers :
Q9UJ71
applications :
Immunoelectron Microscopy,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization
USD :
469 USD
alt names :
CD207, CD207 antigen, CD207 antigen, langerin, CD207 molecule, langerin, CLEC4KLangerhans cell specific c-type lectin, C-type lectin domain family 4 member K, C-type lectin domain family 4, member K, Langerin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.