Mouse Legumain/Asparaginyl Endopeptidase Antibody | R&D Systems AF2058 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Legumain/Asparaginyl Endopeptidase Antibody

catalog :

AF2058

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig s1a, s1b	Chen C, Wang D, Yu Y, Zhao T, Min N, Wu Y, et al. Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI. Cell Death Dis. 2021;12:65 pubmed publisher
	Cason S, Mogre S, Holzbaur E, Koslover E. Spatiotemporal analysis of axonal autophagosome-lysosome dynamics reveals limited fusion events and slow maturation. Mol Biol Cell. 2022;33:ar123 pubmed publisher
	Cao L, Xu C, Yi P, Li H, Lin Y, Cai G, et al. Asparaginyl endopeptidase (AEP) regulates myocardial apoptosis in response to radiation exposure via alterations in NRF2 activation. Am J Cancer Res. 2021;11:1206-1225 pubmed
	Fabbri L, Dufies M, Lacas Gervais S, Gardie B, Gad Lapiteau S, Parola J, et al. Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients. Theranostics. 2020;10:2696-2713 pubmed publisher
	Yamane T, Kozuka M, Yamamoto Y, Nakano Y, Nakagaki T, Ohkubo I, et al. Protease activity of legumain is inhibited by an increase of cystatin E/M in the DJ-1-knockout mouse spleen, cerebrum and heart. Biochem Biophys Rep. 2017;9:187-192 pubmed publisher
	Tan Y, Nie S, Zhu W, Liu F, Guo H, Chu J, et al. 7,8-Dihydroxyflavone Ameliorates Cognitive Impairment by Inhibiting Expression of Tau Pathology in ApoE-Knockout Mice. Front Aging Neurosci. 2016;8:287 pubmed

product information

master code :

AF2058

SKU :

AF2058

product name :

Mouse Legumain/Asparaginyl Endopeptidase Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Legumain/Asparaginyl Endopeptidase Antibody from R&D Systems is a sheep polyclonal antibody to Legumain/Asparaginyl Endopeptidase. This antibody reacts with mouse. The Mouse Legumain/Asparaginyl Endopeptidase Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.

target :

Legumain/Asparaginyl Endopeptidase

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Sheep

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Legumain, Val18-Tyr435, Accession # O89017

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse

specificity :

Detects mouse Legumain in direct ELISAs and Western blots.

gene symbol :

LGMN

top caption :

Detection of Mouse Legumain/Asparaginyl Endopeptidase antibody by Western Blot.

accessionNumbers :

O89017

applications :

Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry

USD :

499 USD

alt names :

AEP, Asparaginyl endopeptidase, cysteine protease 1, legumain, LGMN, LGMN1, Protease, cysteine 1, protease, cysteine, 1 (legumain), PRSC1EC 3.4.22.34

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage