product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat SOX2 Antibody
catalog :
AF2018
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
African green monkey, human, mouse, rat, dogs, chicken, bovine, zebrafish , rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, dot blot
more info or order :
citations: 268
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 6g
Sun H, Wang T, Atkinson P, Billings S, Dong W, Cheng A. Gpr125 Marks Distinct Cochlear Cell Types and Is Dispensable for Cochlear Development and Hearing. Front Cell Dev Biol. 2021;9:690955 pubmed publisher
  • immunohistochemistry; African green monkey; 1:200; loading ...; fig 2c
Hosoya M, Fujioka M, Murayama A, Ogawa K, Okano H, Ozawa H. Dynamic Spatiotemporal Expression Changes in Connexins of the Developing Primate's Cochlea. Genes (Basel). 2021;12: pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig s6f
Mu W, Li S, Xu J, Guo X, Wu H, Chen Z, et al. Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice. Nat Commun. 2021;12:2288 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1b
Montalb xe1 n Loro R, Lassi G, Lozano Ure xf1 a A, Perez Villalba A, Jim xe9 nez Villalba E, Charalambous M, et al. Dlk1 dosage regulates hippocampal neurogenesis and cognition. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • immunocytochemistry; rat; 1:500; fig s3c
Bilodeau C, Shojaie S, Goltsis O, Wang J, Luo D, Ackerley C, et al. TP63 basal cells are indispensable during endoderm differentiation into proximal airway cells on acellular lung scaffolds. NPJ Regen Med. 2021;6:12 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4
Mattar P, Jolicoeur C, Dang T, Shah S, Clark B, Cayouette M. A Casz1-NuRD complex regulates temporal identity transitions in neural progenitors. Sci Rep. 2021;11:3858 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 2b
Exelby K, Herrera Delgado E, Perez L, Perez Carrasco R, Sagner A, Metzis V, et al. Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks. Development. 2021;148: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2k
Sweat M, Sweat Y, Yu W, Su D, Leonard R, Eliason S, et al. The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021;39:761-775 pubmed publisher
Gerner Mauro K, Ellis L, Wang G, Nayak R, Lwigale P, Poch xe9 R, et al. Morphogenic, molecular, and cellular adaptations for unidirectional airflow in the chicken lung. bioRxiv. 2024;: pubmed publisher
Li D, Wang X, Chen K, Shan D, Cui G, Yuan W, et al. IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages. Cell Death Differ. 2024;31:738-752 pubmed publisher
Balashova O, Panoutsopoulos A, Visina O, Selhub J, Knoepfler P, Borodinsky L. Noncanonical function of folate through folate receptor 1 during neural tube formation. Nat Commun. 2024;15:1642 pubmed publisher
Atamian A, Birtele M, Hosseini N, Nguyen T, Seth A, Del Dosso A, et al. Human cerebellar organoids with functional Purkinje cells. Cell Stem Cell. 2024;31:39-51.e6 pubmed publisher
Zhu Q, Liang P, Meng H, Li F, Miao W, Chu C, et al. Stabilization of Pin1 by USP34 promotes Ubc9 isomerization and protein sumoylation in glioma stem cells. Nat Commun. 2024;15:40 pubmed publisher
Zhang Y, Tian K, Wei W, Mi W, Lu F, Liu Z, et al. Translocation of telomerase reverse transcriptase coincided with ATP release in postnatal cochlear supporting cells. Neural Regen Res. 2024;19:1119-1125 pubmed publisher
Zhu C, Ren X, Liu C, Liu Y, Wang Y. Rbm8a regulates neurogenesis and reduces Alzheimer's disease-associated pathology in the dentate gyrus of 5×FAD mice. Neural Regen Res. 2024;19:863-871 pubmed publisher
Saegusa C, Kakegawa W, Miura E, Aimi T, Mogi S, Harada T, et al. Brain-Specific Angiogenesis Inhibitor 3 Is Expressed in the Cochlea and Is Necessary for Hearing Function in Mice. Int J Mol Sci. 2023;24: pubmed publisher
Tao Y, Li X, Dong Q, Kong L, Petersen A, Yan Y, et al. Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells. Nat Biotechnol. 2023;: pubmed publisher
Rao S, Brundu F, Chen Y, Sun Y, Zhu H, Shprintzen R, et al. Aberrant pace of cortical neuron development in brain organoids from patients with 22q11.2 deletion syndrome and schizophrenia. bioRxiv. 2023;: pubmed publisher
Su D, Eliason S, Sun Z, Shao F, Amendt B. Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development. J Biol Chem. 2023;299:105324 pubmed publisher
She L, Li X, Bai M. Generation of an induced pluripotent stem cell line XJHi001-A from a fibronectin glomerulopathy patient carrying a heterozygous NM_212482.2(C.5888-1G > C) mutation in the FN1 gene. Stem Cell Res. 2023;72:103203 pubmed publisher
Rizzoti K, Chakravarty P, Sheridan D, Lovell Badge R. SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context. Sci Adv. 2023;9:eadf6911 pubmed publisher
Jeon H, Shin Y, Lee J, Chang N, Woo D, Lee W, et al. The semaphorin 3A/neuropilin-1 pathway promotes clonogenic growth of glioblastoma via activation of TGF-β signaling. JCI Insight. 2023;8: pubmed publisher
Yin J, Seo Y, Rhim J, Jin X, Kim T, Kim S, et al. Cross-talk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells. Cancer Res. 2023;83:3693-3709 pubmed publisher
Schwartz M, Likhite S, Vetter T, Baird M, McGovern V, Sierra Delgado A, et al. In-depth comparison of Anc80L65 and AAV9 retinal targeting and characterization of cross-reactivity to multiple AAV serotypes in humans. Mol Ther Methods Clin Dev. 2023;30:16-29 pubmed publisher
Militi S, Nibhani R, Jalali M, Pauklin S. RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling. Cell Rep. 2023;42:113146 pubmed publisher
Ortega Gasc xf3 A, Parcerisas A, Hino K, Herranz P xe9 rez V, Ulloa F, Elias Tersa A, et al. Regulation of young-adult neurogenesis and neuronal differentiation by neural cell adhesion molecule 2 (NCAM2). Cereb Cortex. 2023;33:10931-10948 pubmed publisher
Imitola J, Hollingsworth E, Watanabe F, Olah M, Elyaman W, Starossom S, et al. Stat1 is an inducible transcriptional repressor of neural stem cells self-renewal program during neuroinflammation. Front Cell Neurosci. 2023;17:1156802 pubmed publisher
Stanton A, Bubnys A, Agbas E, James B, Park D, Jiang A, et al. Engineered 3D Immuno-Glial-Neurovascular Human Brain Model. bioRxiv. 2023;: pubmed publisher
Ciarpella F, Zamfir R, Campanelli A, Pedrotti G, Di Chio M, Bottani E, et al. Generation of mouse hippocampal brain organoids from primary embryonic neural stem cells. STAR Protoc. 2023;4:102413 pubmed publisher
Chen X, Cui Q, Hu X, Ye J, Liu Z, Mei Y, et al. CD200 in dentate gyrus improves depressive-like behaviors of mice through enhancing hippocampal neurogenesis via alleviation of microglia hyperactivation. J Neuroinflammation. 2023;20:157 pubmed publisher
Wang Y, Peng J, Song C, Yang Y, Qin T. Zinc finger and SCAN domain-containing 18 suppresses the proliferation, self-renewal, and drug resistance of glioblastoma cells. Heliyon. 2023;9:e17000 pubmed publisher
Appiah B, Fullio C, Ossola C, Bertani I, Restelli E, Cheffer A, et al. DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression. EMBO Rep. 2023;24:e56233 pubmed publisher
Chen Y, Chauhan S, Gong C, Dayton H, Xu C, De La Cruz E, et al. Scalable projected Light Sheet Microscopy for high-resolution imaging of living and cleared samples. bioRxiv. 2023;: pubmed publisher
Rawat H, Kornherr J, Zawada D, Bakhshiyeva S, Kupatt C, Laugwitz K, et al. Recapitulating porcine cardiac development in vitro: from expanded potential stem cell to embryo culture models. Front Cell Dev Biol. 2023;11:1111684 pubmed publisher
Rallapalli H, Bayin N, Goldman H, Maric D, Nieman B, Koretsky A, et al. Cell specificity of Manganese-enhanced MRI signal in the cerebellum. Neuroimage. 2023;276:120198 pubmed publisher
Thompson M, Young C, Munnamalai V, Umulis D. Early radial positional information in the cochlea is optimized by a precise linear BMP gradient and enhanced by SOX2. Sci Rep. 2023;13:8567 pubmed publisher
Zhu Z, Chen X, Guo A, Manzano T, Walsh P, Wills K, et al. Mitotic bookmarking by SWI/SNF subunits. Nature. 2023;618:180-187 pubmed publisher
Li Q, Cui C, Liao R, Yin X, Wang D, Cheng Y, et al. The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice. Cell Mol Life Sci. 2023;80:148 pubmed publisher
Sidhaye J, Trepte P, Sepke N, Novatchkova M, Schutzbier M, D xfc rnberger G, et al. Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids. elife. 2023;12: pubmed publisher
Tang X, Wang D, Zhang X, Xu M, Liu Y. Optimized protocol for analysis of neural stem proliferation in human-pluripotent-stem-cell-derived cerebral organoids. STAR Protoc. 2023;4:102169 pubmed publisher
Guyer R, Stavely R, Robertson K, Bhave S, Mueller J, Picard N, et al. Single-cell multiome sequencing clarifies enteric glial diversity and identifies an intraganglionic population poised for neurogenesis. Cell Rep. 2023;42:112194 pubmed publisher
Luo Q, Pui H, Chen J, Yu L, Jannig P, Pei Y, et al. Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence. Cell Rep. 2023;42:112021 pubmed publisher
Campbell N, Patel Y, Moore T, Medalla M, Zeldich E. Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome. Int J Mol Sci. 2023;24: pubmed publisher
Li J, Godoy M, Zhang A, Diamante G, Ahn I, Cebrian Silla A, et al. Prdm16 and Vcam1 regulate the postnatal disappearance of embryonic radial glia and the ending of cortical neurogenesis. bioRxiv. 2023;: pubmed publisher
Wang J, Xu L, Peng D, Zhu Y, Gu Z, Yao Y, et al. IFN-γ-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury. Inflamm Regen. 2023;43:12 pubmed publisher
Tafessu A, O Hara R, Martire S, Dube A, Saha P, Gant V, et al. H3.3 contributes to chromatin accessibility and transcription factor binding at promoter-proximal regulatory elements in embryonic stem cells. Genome Biol. 2023;24:25 pubmed publisher
Zhang F, Yoon K, Zhang D, Kim N, Ming G, Song H. Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m3C modification. Cell Stem Cell. 2023;30:300-311.e11 pubmed publisher
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Kashiwagi T, Takazawa Y, Kagawa T, Taga T. Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia. Inflamm Regen. 2023;43:8 pubmed publisher
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Yelagandula R, Stecher K, Novatchkova M, Michetti L, Michlits G, Wang J, et al. ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers. Nat Cell Biol. 2023;25:42-55 pubmed publisher
Wang M, Liu Y, Wang Z, Qiao L, Ma X, Hu L, et al. An Optogenetic-Controlled Cell Reprogramming System for Driving Cell Fate and Light-Responsive Chimeric Mice. Adv Sci (Weinh). 2023;10:e2202858 pubmed publisher
Lim K, Donovan A, Tang W, Sun D, He P, Pett J, et al. Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease. Cell Stem Cell. 2023;30:20-37.e9 pubmed publisher
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Kim E, Kim J, Kim S, Hong N, Choi S, Park M, et al. The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2. Cell Rep. 2022;41:111626 pubmed publisher
Nakanoh S, Kadiwala J, Pinte L, Morell C, Lenaerts A, Vallier L. Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells. PLoS ONE. 2022;17:e0269122 pubmed publisher
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Su Y, Zhou Y, Bennett M, Li S, Carceles Cordon M, Lu L, et al. A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan. Cell Stem Cell. 2022;29:1594-1610.e8 pubmed publisher
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Drozd A, Mariani L, Guo X, Goitea V, Menezes N, Ferretti E. Progesterone Receptor Modulates Extraembryonic Mesoderm and Cardiac Progenitor Specification during Mouse Gastrulation. Int J Mol Sci. 2022;23: pubmed publisher
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Sun D, Llorà Batlle O, van den Ameele J, Thomas J, He P, Lim K, et al. SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling. EMBO J. 2022;41:e111338 pubmed publisher
Lin J, Mitchell T, Rothstein M, Pehl A, Taroc E, Katreddi R, et al. Sociosexual behavior requires both activating and repressive roles of Tfap2e/AP-2ε in vomeronasal sensory neurons. elife. 2022;11: pubmed publisher
L xf3 pez Anguita N, Gassaloglu S, St xf6 tzel M, Bolondi A, Conkar D, Typou M, et al. Hypoxia induces an early primitive streak signature, enhancing spontaneous elongation and lineage representation in gastruloids. Development. 2022;149: pubmed publisher
Fischer J, Fern xe1 ndez Ortu xf1 o E, Marsoner F, Artioli A, Peters J, Namba T, et al. Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids. EMBO Rep. 2022;23:e54728 pubmed publisher
Zhang J, Lv X, Wei B, Gong X, Chen L. CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer. Cell Signal. 2022;100:110464 pubmed publisher
Place E, Manning E, Kim D, Kinjo A, Nakamura G, Ohyama K. SHH and Notch regulate SOX9+ progenitors to govern arcuate POMC neurogenesis. Front Neurosci. 2022;16:855288 pubmed publisher
Ko C, Biesiada J, Zablon H, Zhang X, Medvedovic M, Puga A. The aryl hydrocarbon receptor directs the differentiation of murine progenitor blastomeres. Cell Biol Toxicol. 2022;: pubmed publisher
Mukherjee S, Luedeke D, McCoy L, Iwafuchi M, Zorn A. SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells. Cell Rep. 2022;40:111247 pubmed publisher
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Ren W, Ma Z, Wang L, Feng X, Yu H, Yu Y. Lgr5+ cells are required and dynamically participate in olfactory epithelium regeneration: a revisiting shows Lgr5 expression in multiple cell lineages. Theranostics. 2022;12:5631-5644 pubmed publisher
Portela M, Jimenez Carretero D, Labrador V, Andreu M, Arza E, Caiolfa V, et al. Chromatin dynamics through mouse preimplantation development revealed by single molecule localisation microscopy. Biol Open. 2022;11: pubmed publisher
Chen T, Alcorn H, Devbhandari S, Remus D, Lacy E, Huangfu D, et al. A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation. Biol Open. 2022;11: pubmed publisher
Rodocker H, Bordbar A, Larson M, Biltz R, Wangler L, Fadda P, et al. Breaking Mental Barriers Promotes Recovery After Spinal Cord Injury. Front Mol Neurosci. 2022;15:868563 pubmed publisher
Hamed A, Kunz D, El Hamamy I, Trinh Q, Subedar O, Richards L, et al. A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours. Nat Commun. 2022;13:4178 pubmed publisher
Li D, Zhang Q, Li L, Chen K, Yang J, Dixit D, et al. β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages. Cancer Res. 2022;82:3321-3334 pubmed publisher
Kim I, Lee T, Lee J, Kim J, Lee S, Koh I, et al. Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder. Mol Psychiatry. 2022;27:4680-4694 pubmed publisher
Kedia S, Aghanoori M, Burns K, Subha M, Williams L, Wen P, et al. Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation. Cell Rep. 2022;40:111070 pubmed publisher
Dong X, Chen Y, Lu J, Huang S, Pei G. β-arrestin 2 and Epac2 cooperatively mediate DRD1-stimulated proliferation of human neural stem cells and growth of human cerebral organoids. Stem Cells. 2022;: pubmed publisher
Thomas R, Menon V, Mani R, Pruszak J. Glycan Epitope and Integrin Expression Dynamics Characterize Neural Crest Epithelial-to-Mesenchymal Transition (EMT) in Human Pluripotent Stem Cell Differentiation. Stem Cell Rev Rep. 2022;18:2952-2965 pubmed publisher
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Dar N, Na R, Ran Q. Functional Deficits of 5×FAD Neural Stem Cells Are Ameliorated by Glutathione Peroxidase 4. Cells. 2022;11: pubmed publisher
Hein R, Wu J, Holloway E, Frum T, Conchola A, Tsai Y, et al. R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development. Dev Cell. 2022;57:1598-1614.e8 pubmed publisher
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Sawada K. Neurogenesis of Subventricular Zone Progenitors in the Premature Cortex of Ferrets Facilitated by Neonatal Valproic Acid Exposure. Int J Mol Sci. 2022;23: pubmed publisher
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Yang Y, Chen X, Tian K, Tian C, Chen L, Mi W, et al. Heme Oxygenase-1 Protects Hair Cells From Gentamicin-Induced Death. Front Cell Neurosci. 2022;16:783346 pubmed publisher
Rostovskaya M, Andrews S, Reik W, Rugg Gunn P. Amniogenesis occurs in two independent waves in primates. Cell Stem Cell. 2022;29:744-759.e6 pubmed publisher
Liu Y, Ling T, Wang H, Yang Y, Song W, Wang T. Generation of an integration-free induced pluripotent stem cell line (LZUSHI001-A) from an epileptic patient with DGKG mutation. Stem Cell Res. 2022;61:102768 pubmed publisher
Kadur Lakshminarasimha Murthy P, Sontake V, Tata A, Kobayashi Y, Macadlo L, Okuda K, et al. Human distal lung maps and lineage hierarchies reveal a bipotent progenitor. Nature. 2022;604:111-119 pubmed publisher
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Taubenschmid Stowers J, Rostovskaya M, Santos F, Ljung S, Argelaguet R, Krueger F, et al. 8C-like cells capture the human zygotic genome activation program in vitro. Cell Stem Cell. 2022;29:449-459.e6 pubmed publisher
Rastoldo G, Marouane E, El Mahmoudi N, P xe9 ricat D, Watabe I, Lapôtre A, et al. L-Thyroxine Improves Vestibular Compensation in a Rat Model of Acute Peripheral Vestibulopathy: Cellular and Behavioral Aspects. Cells. 2022;11: pubmed publisher
Borisova E, Nishimura K, An Y, Takami M, Li J, Song D, et al. Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency. iScience. 2022;25:103525 pubmed publisher
Budjan C, Liu S, Ranga A, Gayen S, Pourqui xe9 O, Hormoz S. Paraxial mesoderm organoids model development of human somites. elife. 2022;11: pubmed publisher
Lopez Fabuel I, García Macia M, Buondelmonte C, Burmistrova O, Bonora N, Alonso Batan P, et al. Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis. Nat Commun. 2022;13:536 pubmed publisher
de Wet L, Williams A, Gillard M, Kregel S, Lamperis S, Gutgesell L, et al. SOX2 mediates metabolic reprogramming of prostate cancer cells. Oncogene. 2022;41:1190-1202 pubmed publisher
Eicher A, Kechele D, Sundaram N, Berns H, Poling H, Haines L, et al. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell Stem Cell. 2022;29:36-51.e6 pubmed publisher
Sundar S, Shakya S, Barnett A, Wallace L, Jeon H, Sloan A, et al. Three-dimensional organoid culture unveils resistance to clinical therapies in adult and pediatric glioblastoma. Transl Oncol. 2022;15:101251 pubmed publisher
Chen F, Liu J, Song X, DuCote T, Byrd A, Wang C, et al. EZH2 inhibition confers PIK3CA-driven lung tumors enhanced sensitivity to PI3K inhibition. Cancer Lett. 2022;524:151-160 pubmed publisher
Christopher G, Noort R, Esseltine J. Connexin 43 Gene Ablation Does Not Alter Human Pluripotent Stem Cell Germ Lineage Specification. Biomolecules. 2021;12: pubmed publisher
Ciarpella F, Zamfir R, Campanelli A, Ren E, Pedrotti G, Bottani E, et al. Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity. iScience. 2021;24:103438 pubmed publisher
Liu Y, Wu Z, Zhou J, Ramadurai D, Mortenson K, Aguilera Jimenez E, et al. A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer. Nat Commun. 2021;12:7139 pubmed publisher
Arredondo S, Reyes D, Herrera Soto A, Mardones M, Inestrosa N, Varela Nallar L. Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease. Sci Rep. 2021;11:22904 pubmed publisher
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product information
brand :
R&D Systems
master code :
AF2018
SKU :
AF2018
product name :
Human/Mouse/Rat SOX2 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat SOX2 Antibody from R&D Systems is a goat polyclonal antibody to SOX2. This antibody reacts with avian - chicken,avian - quail,bovine,canine,chicken,ferret,fish,human,mouse,primate - callithrix jacchus (common marmoset),primate - macaca mulatta (rhesus macaque),rat,transgenic mouse,xenograft,fish - danio rerio (zebrafish),frog - xenopus (african clawed frog),insect - aedes albopictus (asian tiger mosquito). The Human/Mouse/Rat SOX2 Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Flow Cytomery,Western Blot,Flow Cyomtetry,ICC-IF,Bioassay,Binding Assay,Co-Immunoprecipitation,Flow Cytometry,Immunoprecipitation,Dot Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,Chromatin Immunoprecipitation (ChIP),RNAscope compatible,Immunocytochemistry/ Immunofluorescence,Simple Western.
target :
SOX2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Simple Western 5 ug/mL, Immunohistochemistry 3-25 ug/mL, Chromatin Immunoprecipitation (ChIP) 5 ug/5 x 10^6 cells, Immunocytochemistry 5-15 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human SOX2, Gly135-Met317, Accession # P48431
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Avian - Chicken,Avian - Quail,Bovine,Canine,Chicken,Ferret,Fish,Human,Mouse,Primate - Callithrix jacchus (Common Marmoset),Primate - Macaca mulatta (Rhesus Macaque),Rat,Transgenic Mouse,Xenograft,Fish - Danio rerio (Zebrafish),Frog - Xenopus (African Clawed Frog),Insect - Aedes albopictus (Asian tiger mosquito)
specificity :
Detects human SOX2 in direct ELISAs and Western blots.
gene symbol :
SOX2
top caption :
Detection of Human, Mouse, and Rat SOX2 antibody by Western Blot.
accessionNumbers :
P48431
applications :
Simple Western,Bioassay,Binding Assay,Co-Immunoprecipitation,Flow Cyomtetry,ICC-IF,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Dot Blot,Immunofluorescence,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry,RNAscope compatible,Immunocytochemistry/ Immunofluorescence
USD :
499 USD
alt names :
ANOP3, MCOPS3, MGC2413, SRY (sex determining region Y)-box 2, SRY-related HMG-box gene 2, transcription factor SOX2, transcription factor SOX-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.