Human RUNX2/CBFA1 Antibody | R&D Systems AF2006 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human RUNX2/CBFA1 Antibody

catalog :

AF2006

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 6b	Ding R, Li H, Liu Y, Ou W, Zhang X, Chai H, et al. Activating cGAS-STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis. J Neuroinflammation. 2022;19:137 pubmed publisher
	Polsani N, Yung T, Thomas E, Phung Rojas M, Gupta I, Denker J, et al. Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion. bioRxiv. 2023;: pubmed publisher
	Feng X, Molteni H, Gregory M, Lanza J, Polsani N, Wyetzner R, et al. Apical expansion of calvarial osteoblasts and suture patency is dependent on graded fibronectin cues. bioRxiv. 2023;: pubmed publisher
	Minguzzi M, Panichi V, D Adamo S, Cetrullo S, Cattini L, Flamigni F, et al. Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes. Int J Mol Sci. 2021;22: pubmed publisher
	Somemura S, Kumai T, Yatabe K, Sasaki C, Fujiya H, Niki H, et al. Physiologic Mechanical Stress Directly Induces Bone Formation by Activating Glucose Transporter 1 (Glut 1) in Osteoblasts, Inducing Signaling via NAD+-Dependent Deacetylase (Sirtuin 1) and Runt-Related Transcription Factor 2 (Runx2). Int J Mol Sci. 2021;22: pubmed publisher
	Hu L, Liu J, Xue H, Panayi A, Xie X, Lin Z, et al. miRNA-92a-3p regulates osteoblast differentiation in patients with concomitant limb fractures and TBI via IBSP/PI3K-AKT inhibition. Mol Ther Nucleic Acids. 2021;23:1345-1359 pubmed publisher
	Wu C, Zhang B, Kim H, Anderson S, Miller J, Cichocki F. Ascorbic Acid Promotes KIR Demethylation during Early NK Cell Differentiation. J Immunol. 2020;205:1513-1523 pubmed publisher
	Millar S, John S, McIntyre C, Ralevic V, Anderson S, O Sullivan S. An Investigation Into the Role of Osteocalcin in Human Arterial Smooth Muscle Cell Calcification. Front Endocrinol (Lausanne). 2020;11:369 pubmed publisher

product information

master code :

AF2006

SKU :

AF2006

product name :

Human RUNX2/CBFA1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human RUNX2/CBFA1 Antibody from R&D Systems is a goat polyclonal antibody to RUNX2/CBFA1. This antibody reacts with human,transgenic mouse. The Human RUNX2/CBFA1 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunocytochemistry,Chromatin Immunoprecipitation (ChIP).

target :

RUNX2/CBFA1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human RUNX2/CBFA1 isoform 2, Lys219-Tyr404, Accession # Q13950

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Transgenic Mouse

specificity :

Detects human RUNX2/CBFA1 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) RUNX1 and rhRUNX3 is observed.

gene symbol :

RUNX2

top caption :

Detection of RUNX2/CBFA1-regulated Genes antibody by Chromatin Immunoprecipitation.

accessionNumbers :

Q13950

applications :

Western Blot,Immunohistochemistry,Immunocytochemistry,Chromatin Immunoprecipitation (ChIP)

USD :

469 USD

alt names :

Acute myeloid leukemia 3 protein, CBFA1, CBF-alpha-1, CCD1, CCDAML3, CLCD, Core-binding factor subunit alpha-1, core-binding factor, runt domain, alpha subunit 1, MGC120023, ML3, oncogene AML-3, OSF2, OSF-2, osteoblast-specific transcription factor 2, PEA2aA, PEA2-alpha A, PEBP2A, PEBP2aA, PEBP2-alpha A, polyomavirus enhancer-binding protein 2 alpha A subunit, runt domain, alpha subunit 1, runt related transcription factor 2, runt-related transcription factor 2, RUNX2, SL3/AKV core-binding factor alpha A subunit, SL3-3 enhancer factor 1 alpha A subunit

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage