Mouse Endocan/ESM-1 Antibody | R&D Systems AF1999 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Endocan/ESM-1 Antibody

catalog :

AF1999

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, neutralization, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 17

Reference
Lee E, Lee E, Kong E, Chon H, Llaiqui Condori M, Park C, et al. An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone. Exp Mol Med. 2023;55:470-484 pubmed publisher
Kuo A, Checa A, Niaudet C, Jung B, Fu Z, Wheelock C, et al. Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis. elife. 2022;11: pubmed publisher
Bae J, Yang M, Jeong S, Kim J, Hong S, Kim J, et al. Gatekeeping role of Nf2/Merlin in vascular tip EC induction through suppression of VEGFR2 internalization. Sci Adv. 2022;8:eabn2611 pubmed publisher
Tedeschi T, Lee K, Zhu W, Fawzi A. Limited hyperoxia-induced proliferative retinopathy: A model of persistent retinal vascular dysfunction, preretinal fibrosis and hyaloidal vascular reprogramming for retinal rescue. PLoS ONE. 2022;17:e0267576 pubmed publisher
Ben Dhaou C, Mandi K, Frye M, Acheampong A, Radi A, De Becker B, et al. Chemerin regulates normal angiogenesis and hypoxia-driven neovascularization. Angiogenesis. 2022;25:159-179 pubmed publisher
Zarkada G, Howard J, Xiao X, Park H, Bizou M, Leclerc S, et al. Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation. Dev Cell. 2021;56:2237-2251.e6 pubmed publisher
Brücher V, Egbring C, Plagemann T, Nedvetsky P, Höffken V, Pavenstadt H, et al. Lack of WWC2 Protein Leads to Aberrant Angiogenesis in Postnatal Mice. Int J Mol Sci. 2021;22: pubmed publisher
Malinova T, Angulo Urarte A, Nüchel J, Tauber M, van der Stoel M, Janssen V, et al. A junctional PACSIN2/EHD4/MICAL-L1 complex coordinates VE-cadherin trafficking for endothelial migration and angiogenesis. Nat Commun. 2021;12:2610 pubmed publisher
Dani N, Herbst R, McCabe C, Green G, Kaiser K, Head J, et al. A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021;184:3056-3074.e21 pubmed publisher
Ichijo R, Kabata M, Kidoya H, Muramatsu F, Ishibashi R, Abe K, et al. Vasculature-driven stem cell population coordinates tissue scaling in dynamic organs. Sci Adv. 2021;7: pubmed publisher
Zhang Y, Chen P, Cai S, Li J, Chen Y. Decreased expression of endothelial cell specific molecule-1 in lung tissue in emphysematous mice and stable COPD patients. Iran J Basic Med Sci. 2020;23:1610-1617 pubmed publisher
Chen J, Lippo L, Labella R, Tan S, Marsden B, Dustin M, et al. Decreased blood vessel density and endothelial cell subset dynamics during ageing of the endocrine system. EMBO J. 2021;40:e105242 pubmed publisher
Grant Z, Whitehead L, Wong V, He Z, Yan R, Miles A, et al. Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy. J Clin Invest. 2020;130:4235-4251 pubmed publisher
Yanagida K, Engelbrecht E, Niaudet C, Jung B, Gaengel K, Holton K, et al. Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization. Dev Cell. 2020;52:779-793.e7 pubmed publisher
Vila Ellis L, Cain M, Hutchison V, Flodby P, Crandall E, Borok Z, et al. Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. 2020;52:617-630.e6 pubmed publisher
Zhao X, Nedvetsky P, Stanchi F, Vion A, Popp O, Zühlke K, et al. Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1. elife. 2019;8: pubmed publisher
Su T, Zhong Y, Demetriades A, Shen J, Sui A, Yao Y, et al. Endocan Blockade Suppresses Experimental Ocular Neovascularization in Mice. Invest Ophthalmol Vis Sci. 2018;59:930-939 pubmed publisher

product information

master code :

AF1999

SKU :

AF1999

product name :

Mouse Endocan/ESM-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Endocan/ESM-1 Antibody from R&D Systems is a goat polyclonal antibody to Endocan/ESM-1. This antibody reacts with mouse,transgenic mouse. The Mouse Endocan/ESM-1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization.

target :

Endocan/ESM-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Endocan/ESM-1, Trp20-Arg184, Accession # Q9QYY7

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse Endocan/ESM-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant human Endocan is observed.

gene symbol :

ESM1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Endocan/ESM-1 antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr).

accessionNumbers :

Q9QYY7

applications :

Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization

USD :

489 USD

alt names :

endocan, endothelial cell-specific molecule 1, ESM1, ESM-1, IGFBP-rp6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage