Human Phospho-MSPR/Ron (Y1238/Y1239) Antibody | R&D Systems AF1947 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Phospho-MSPR/Ron (Y1238/Y1239) Antibody

catalog :

AF1947

quantity :

100 ug (also 25 ug)

price :

419 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 9

Reference
Hayashi S, Craddock B, Miller W. Effects of heterologous kinase domains on growth factor receptor specificity. Cell Signal. 2024;122:111307 pubmed publisher
Gurska L, Okabe R, Schurer A, Tong M, Soto M, Choi D, et al. Crizotinib Has Preclinical Efficacy in Philadelphia-Negative Myeloproliferative Neoplasms. Clin Cancer Res. 2023;29:943-956 pubmed publisher
Beauvais D, Nelson S, Adams K, Stueven N, Jung O, Rapraeger A. Plasma membrane proteoglycans syndecan-2 and syndecan-4 engage with EGFR and RON kinase to sustain carcinoma cell cycle progression. J Biol Chem. 2022;298:102029 pubmed publisher
Franco Nitta C, Green E, Jhamba E, Keth J, Ortiz Caraveo I, Grattan R, et al. EGFR transactivates RON to drive oncogenic crosstalk. elife. 2021;10: pubmed publisher
Yu Q, Wang J, Li T, Guo X, Ding S, Che X, et al. Recepteur d'origine nantais contributes to the development of endometriosis via promoting epithelial-mesenchymal transition of a endometrial epithelial cells. J Cell Mol Med. 2021;25:1601-1612 pubmed publisher
Dustin D, Gu G, Beyer A, Herzog S, Edwards D, Lin H, et al. RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer. Br J Cancer. 2021;124:191-206 pubmed publisher
Berning P, Hennemann C, Tulotta C, Schaefer C, Lechtape B, Hotfilder M, et al. The Receptor Tyrosine Kinase RON and Its Isoforms as Therapeutic Targets in Ewing Sarcoma. Cancers (Basel). 2020;12: pubmed publisher
Balmaña M, Diniz F, Feijão T, Barrias C, Mereiter S, Reis C. Analysis of the Effect of Increased α2,3-Sialylation on RTK Activation in MKN45 Gastric Cancer Spheroids Treated with Crizotinib. Int J Mol Sci. 2020;21: pubmed publisher
Graves Deal R, Bogatcheva G, Rehman S, Lu Y, Higginbotham J, Singh B. Broad-spectrum receptor tyrosine kinase inhibitors overcome de novo and acquired modes of resistance to EGFR-targeted therapies in colorectal cancer. Oncotarget. 2019;10:1320-1333 pubmed publisher

product information

master code :

AF1947

SKU :

AF1947

product name :

Human Phospho-MSPR/Ron (Y1238/Y1239) Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Phospho-MSPR/Ron (Y1238/Y1239) Antibody from R&D Systems is a rabbit polyclonal antibody to MSPR/Ron. This antibody reacts with human,mouse. The Human Phospho-MSPR/Ron (Y1238/Y1239) Antibody has been validated for the following applications: Western Blot,Immunoprecipitation,Immunohistochemistry,Immunocytochemistry.

target :

MSPR/Ron

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Phosphopeptide containing human MSP R/Ron Y1238/Y1239 sites

isotype :

IgG

purity :

Antigen and protein A Affinity-purified

species :

Human,Mouse

specificity :

The antibody detects endogenous human MSP R/Ron phosphorylated at Y1238/Y1239 using Western blots.

gene symbol :

MST1R

top caption :

Detection of Human Phospho-MSP R/Ron (Y1238/Y1239) antibody by Western Blot.

applications :

Western Blot,Immunoprecipitation,Immunohistochemistry,Immunocytochemistry

USD :

419 USD

alt names :

CD136, CD136 antigen, CDw136c-met-related tyrosine kinase, EC 2.7.10, EC 2.7.10.1, macrophage stimulating 1 receptor (c-met-related tyrosine kinase), MSP R, MSP receptor, MST1R, p185-Ron, Protein-tyrosine kinase 8, PTK8, PTK8 protein tyrosine kinase 8, Ron, RONmacrophage-stimulating protein receptor, soluble RON variant 1, soluble RON variant 2, soluble RON variant 3, soluble RON variant 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage