Human BCMA/TNFRSF17 Antibody | R&D Systems AF193 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BCMA/TNFRSF17 Antibody

catalog :

AF193

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 3

Reference
Da Vià M, Dietrich O, Truger M, Arampatzi P, Duell J, Heidemeier A, et al. Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma. Nat Med. 2021;27:616-619 pubmed publisher
Bu D, Singh R, Choi E, Ruella M, Nunez Cruz S, Mansfield K, et al. Pre-clinical validation of B cell maturation antigen (BCMA) as a target for T cell immunotherapy of multiple myeloma. Oncotarget. 2018;9:25764-25780 pubmed publisher
Saulep Easton D, Vincent F, Quah P, Wei A, Ting S, Croce C, et al. The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells. Leukemia. 2016;30:163-72 pubmed publisher

product information

master code :

AF193

SKU :

AF193

product name :

Human BCMA/TNFRSF17 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human BCMA/TNFRSF17 Antibody from R&D Systems is a goat polyclonal antibody to BCMA/TNFRSF17. This antibody reacts with human. The Human BCMA/TNFRSF17 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,ELISA,Western Blot,Blockade of Receptor-ligand Interaction,ELISA Capture (Matched Antibody Pair),CyTOF-ready.

target :

BCMA/TNFRSF17

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human BCMA/TNFRSF17, Met1-Ala54, Accession # Q6PE46

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human BCMA in ELISAs and Western blots. In sandwich ELISAs, less than 0.1% cross-reactivity with recombinant human (rh) APRIL, rhBAFF, rhTACI, and recombinant mouse BCMA is observed.

gene symbol :

TNFRSF17

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of BCMA/TNFRSF17 antibody in U266 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q6PE46

applications :

Flow Cytometry,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,ELISA,Western Blot,Blockade of Receptor-ligand Interaction,ELISA Capture (Matched Antibody Pair),CyTOF-ready

USD :

489 USD

alt names :

B cell maturation antigen, B-cell maturation protein, BCMAtumor necrosis factor receptor superfamily member 17, BCMB-cell maturation factor, CD269, CD269 antigen, TNFRSF13A, TNFRSF17, tumor necrosis factor receptor superfamily, member 17

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage