Human Dectin-1/CLEC7A Antibody | R&D Systems AF1859 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Dectin-1/CLEC7A Antibody

catalog :

AF1859

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 3

Reference
Haji S, Ito T, Guenther C, Nakano M, Shimizu T, Mori D, et al. Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2. elife. 2022;11: pubmed publisher
Griffiths J, Thompson A, Stott M, Benny A, Lewis N, Taylor P, et al. Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases. FASEB J. 2018;32:3385-3397 pubmed publisher
Zhao G, Hu M, Li C, Lee J, Yuan K, Zhu G, et al. Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitis. Immunol Cell Biol. 2018;96:401-412 pubmed publisher

product information

master code :

AF1859

SKU :

AF1859

product name :

Human Dectin-1/CLEC7A Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Dectin-1/CLEC7A Antibody from R&D Systems is a goat polyclonal antibody to Dectin-1/CLEC7A. This antibody reacts with human,mouse. The Human Dectin-1/CLEC7A Antibody has been validated for the following applications: Western Blot,Neutralization,Immunocytochemistry,Blockade of Receptor-ligand Interaction.

target :

Dectin-1/CLEC7A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Dectin-1/CLEC7A (R D Systems, Catalog # 1859-DC), Thr66-Met201, Accession # NP_072092

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human Dectin-1/CLEC7A in direct ELISAs and Western blots. In this format, less than 2% cross-reactivity with recombinant mouse Dectin-1 and recombinant human Dectin-2 is observed.

gene symbol :

CLEC7A

endotoxin note :

<2.0 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

NP_072092

applications :

Western Blot,Neutralization,Immunocytochemistry,Blockade of Receptor-ligand Interaction

USD :

469 USD

alt names :

Beta-glucan receptor, BGR, CD369, CLEC7A, CLECSF12, CLECSF12DC-associated C-type lectin 1, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, dectin-1, Dectin1, DECTIN1CANDF4, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, hDectin-1, lectin-like receptor 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage