product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human Islet-1 Antibody
catalog :
AF1837
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:1000; fig 2d
Exelby K, Herrera Delgado E, Perez L, Perez Carrasco R, Sagner A, Metzis V, et al. Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks. Development. 2021;148: pubmed publisher
Petrova V, Snavely A, Splaine J, Zhen S, Singh B, Pandey R, et al. Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons. Cell Mol Life Sci. 2024;81:315 pubmed publisher
Ondatje B, Sances S, Workman M, Svendsen C. Tissue clearing of human iPSC-derived organ-chips enables high resolution imaging and analysis. Lab Chip. 2022;22:4246-4255 pubmed publisher
Maruyama K, Miyagawa Tomita S, Haneda Y, Kida M, Matsuzaki F, Imanaka Yoshida K, et al. The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse. elife. 2022;11: pubmed publisher
Albrecht N, Jiang D, Akhanov V, Hobson R, Speer C, Robichaux M, et al. Rapid 3D-STORM imaging of diverse molecular targets in tissue. Cell Rep Methods. 2022;2:100253 pubmed publisher
Januel C, Menduti G, Mamchaoui K, Martinat C, Artero R, Konieczny P, et al. Moxifloxacin rescues SMA phenotypes in patient-derived cells and animal model. Cell Mol Life Sci. 2022;79:441 pubmed publisher
Gupta S, Kawaguchi R, Heinrichs E, Gallardo S, Castellanos S, Mandric I, et al. In vitro atlas of dorsal spinal interneurons reveals Wnt signaling as a critical regulator of progenitor expansion. Cell Rep. 2022;40:111119 pubmed publisher
Ohgushi M, Taniyama N, Vandenbon A, Eiraku M. Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model. Cell Rep. 2022;39:110973 pubmed publisher
González Terán B, Pittman M, Felix F, Thomas R, Richmond Buccola D, Hüttenhain R, et al. Transcription factor protein interactomes reveal genetic determinants in heart disease. Cell. 2022;185:794-814.e30 pubmed publisher
Zhou X, Lu Y, Zhao F, Dong J, Ma W, Zhong S, et al. Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development. Cell Stem Cell. 2022;29:328-343.e5 pubmed publisher
Cunningham J, Scripter J, Nti S, Tucker E. Early construction of the thalamocortical axon pathway requires c-Jun N-terminal kinase signaling within the ventral forebrain. Dev Dyn. 2022;251:459-480 pubmed publisher
Talley M, Nardini D, Qin S, Prada C, Ehrman L, Waclaw R. A role for sustained MAPK activity in the mouse ventral telencephalon. Dev Biol. 2021;476:137-147 pubmed publisher
Gupta S, Yamauchi K, Novitch B, Butler S. Derivation of dorsal spinal sensory interneurons from human pluripotent stem cells. STAR Protoc. 2021;2:100319 pubmed publisher
Ewan E, Avraham O, Carlin D, Gonçalves T, Zhao G, Cavalli V. Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism. Sci Rep. 2021;11:374 pubmed publisher
Ho R, Workman M, Mathkar P, Wu K, Kim K, O Rourke J, et al. Cross-Comparison of Human iPSC Motor Neuron Models of Familial and Sporadic ALS Reveals Early and Convergent Transcriptomic Disease Signatures. Cell Syst. 2021;12:159-175.e9 pubmed publisher
Zhang L, Avery J, Yin A, Singh A, Cliff T, Yin H, et al. Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State. Cell Stem Cell. 2020;27:784-797.e11 pubmed publisher
Coyne A, Zaepfel B, Hayes L, Fitchman B, Salzberg Y, Luo E, et al. G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD. Neuron. 2020;107:1124-1140.e11 pubmed publisher
Kim E, Jiang M, Huang H, Zhang Y, Tjota N, Gao X, et al. Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation. Dev Cell. 2019;51:675-683.e4 pubmed publisher
Jiang D, Burger C, Casasent A, Albrecht N, Li F, Samuel M. Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae. J Comp Neurol. 2019;: pubmed publisher
Frendo M, da Silva A, Phan K, Riche S, Butler S. The Cofilin/Limk1 Pathway Controls the Growth Rate of Both Developing and Regenerating Motor Axons. J Neurosci. 2019;39:9316-9327 pubmed publisher
Drowley L, McPheat J, Nordqvist A, Peel S, Karlsson U, Martinsson S, et al. Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach. Stem Cells Transl Med. 2020;9:47-60 pubmed publisher
Carlin D, Halevi A, Ewan E, Moore A, Cavalli V. Nociceptor deletion of Tsc2 enhances axon regeneration by inducing a conditioning injury response in dorsal root ganglia. Eneuro. 2019;: pubmed publisher
Colunga T, Hayworth M, Kreß S, Reynolds D, Chen L, Nazor K, et al. Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair. Cell Rep. 2019;26:2566-2579.e10 pubmed publisher
Waclaw R, Ehrman L, Merchan Sala P, Kohli V, Nardini D, Campbell K. Foxo1 is a downstream effector of Isl1 in direct pathway striatal projection neuron development within the embryonic mouse telencephalon. Mol Cell Neurosci. 2017;80:44-51 pubmed publisher
Woo C, Maier V, Davey R, Brennan J, Li G, Brothers J, et al. Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy. Proc Natl Acad Sci U S A. 2017;114:E1509-E1518 pubmed publisher
Milani P, Escalante Chong R, Shelley B, Patel Murray N, Xin X, Adam M, et al. Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells. Sci Rep. 2016;6:25474 pubmed publisher
product information
master code :
AF1837
SKU :
AF1837
product name :
Human Islet-1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Islet-1 Antibody from R&D Systems is a goat polyclonal antibody to Islet-1. This antibody reacts with avian - chicken,human,mouse,transgenic mouse. The Human Islet-1 Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Simple Western.
target :
Islet-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human Islet-1, Met4-Ala349, Accession # P61371
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Avian - Chicken,Human,Mouse
specificity :
Detects human Islet-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human Islet-2 is observed.
gene symbol :
ISL1
top caption :
Detection of Human Islet-1 antibody by Western Blot.
accessionNumbers :
P61371
applications :
Immunohistochemistry,Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Simple Western
USD :
509 USD
alt names :
insulin gene enhancer protein ISL-1, ISL LIM homeobox 1, Isl-1, ISL1, ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain, (islet-1), Islet-1, ISLET1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.