product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse IL-27 p28/IL-30 Antibody
catalog :
AF1834
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, neutralization
more info or order :
R&D Systems product webpage
citations: 8
Reference
Zhao M, Zheng Z, Zhang P, Xu Y, Zhang J, Peng S, et al. IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis. iScience. 2023;26:107544 pubmed publisher
Sorrentino C, D Antonio L, Ciummo S, Fieni C, Landuzzi L, Ruzzi F, et al. CRISPR/Cas9-mediated deletion of Interleukin-30 suppresses IGF1 and CXCL5 and boosts SOCS3 reducing prostate cancer growth and mortality. J Hematol Oncol. 2022;15:145 pubmed publisher
Faustino L, Griffith J, Rahimi R, Nepal K, Hamilos D, CHO J, et al. Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung. Nat Immunol. 2020;21:1371-1383 pubmed publisher
Mizoguchi I, Ohashi M, Hasegawa H, Chiba Y, Orii N, Inoue S, et al. EBV-induced gene 3 augments IL-23Rα protein expression through a chaperone calnexin. J Clin Invest. 2020;130:6124-6140 pubmed publisher
Cav xe9 M, Maillard S, Hildenbrand K, Mamelonet C, Feige M, Devergne O. Glycosaminoglycans bind human IL-27 and regulate its activity. Eur J Immunol. 2020;50:1484-1499 pubmed publisher
Pérez Cabezas B, Cecílio P, Robalo A, Silvestre R, Carrillo E, Moreno J, et al. Interleukin-27 Early Impacts Leishmania infantum Infection in Mice and Correlates with Active Visceral Disease in Humans. Front Immunol. 2016;7:478 pubmed
Tang H, Zhang J, Sun X, Qian X, Zhang Y, Jin R. Thymic DCs derived IL-27 regulates the final maturation of CD4(+) SP thymocytes. Sci Rep. 2016;6:30448 pubmed publisher
Rothhammer V, Mascanfroni I, Bunse L, Takenaka M, Kenison J, Mayo L, et al. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor. Nat Med. 2016;22:586-97 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1834
SKU :
AF1834
product name :
Mouse IL-27 p28/IL-30 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse IL-27 p28/IL-30 Antibody from R&D Systems is a goat polyclonal antibody to IL-27 p28/IL-30. This antibody reacts with human,mouse. The Mouse IL-27 p28/IL-30 Antibody has been validated for the following applications: ELISA Development,Western Blot,Neutralization,ELISA Capture,Immunohistochemistry.
target :
IL-27 p28/IL-30
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 1-5 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse IL-27 p28/IL-30, Phe29-Ser234, Accession # Q8K3I6
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects mouse IL-27 p28/IL-30 in direct ELISAs and Western blots.
gene symbol :
Il27
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
IL-27 p28/IL-30 antibody in Mouse Thymus by Immunohistochemistry (IHC-P).
accessionNumbers :
Q8K3I6
applications :
Immunohistochemistry,ELISA Development,Western Blot,Neutralization,ELISA Capture
USD :
499 USD
alt names :
IL27 p28, IL27;IL-27;IL27A;IL-27A;IL27p28;IL-27p28;IL30;p28, IL-30
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.