product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse TIM-1/KIM-1/HAVCR Antibody
catalog :
AF1817
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 95
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig e4b
Mishima E, Ito J, Wu Z, Nakamura T, Wahida A, Doll S, et al. A non-canonical vitamin K cycle is a potent ferroptosis suppressor. Nature. 2022;608:778-783 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 1a
Ranea Robles P, Portman K, Bender A, Lee K, He J, Mulholland D, et al. Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice. Kidney360. 2021;2:1441-1454 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2b
Marquez Exposito L, Tejedor Santamaria L, Santos Sánchez L, Valentijn F, Cantero Navarro E, Rayego Mateos S, et al. Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes. Front Pharmacol. 2021;12:662020 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1c
Yang Y, Cai F, Zhou N, Liu S, Wang P, Zhang S, et al. Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2. Clin Transl Med. 2021;11:e382 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 13a
Alawi L, Dhakal S, Emberesh S, Sawant H, Hosawi A, Thanekar U, et al. Effects of Angiotensin II Type 1A Receptor on ACE2, Neprilysin and KIM-1 in Two Kidney One Clip (2K1C) Model of Renovascular Hypertension. Front Pharmacol. 2020;11:602985 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2f
Xia W, Li Y, Wu M, Jin Q, Wang Q, Li S, et al. Gasdermin E deficiency attenuates acute kidney injury by inhibiting pyroptosis and inflammation. Cell Death Dis. 2021;12:139 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1a
Arita M, Watanabe S, Aoki N, Kuwahara S, Suzuki R, Goto S, et al. Combination therapy of cisplatin with cilastatin enables an increased dose of cisplatin, enhancing its antitumor effect by suppression of nephrotoxicity. Sci Rep. 2021;11:750 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 8f
Ying W, Li X, Rangarajan S, Feng W, Curtis L, Sanders P. Immunoglobulin light chains generate proinflammatory and profibrotic kidney injury. J Clin Invest. 2019;129:2792-2806 pubmed publisher
  • immunohistochemistry; mouse; 1:800; loading ...; fig 4b
  • western blot; mouse; loading ...; fig 2d
Li L, Kang H, Zhang Q, D Agati V, Al Awqati Q, Lin F. FoxO3 activation in hypoxic tubules prevents chronic kidney disease. J Clin Invest. 2019;129:2374-2389 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 6
Konkalmatt P, Asico L, Zhang Y, Yang Y, Drachenberg C, Zheng X, et al. Renal rescue of dopamine D2 receptor function reverses renal injury and high blood pressure. JCI Insight. 2016;1: pubmed
  • immunohistochemistry; mouse; fig 5d
  • western blot; mouse; fig 6f
Ishida R, Kami D, Kusaba T, Kirita Y, Kishida T, Mazda O, et al. Kidney-specific Sonoporation-mediated Gene Transfer. Mol Ther. 2016;24:125-34 pubmed publisher
Hirashima Y, Nakano T, Torisu K, Aihara S, Wakisaka M, Kitazono T. SGLT2 inhibition mitigates transition from acute kidney injury to chronic kidney disease by suppressing ferroptosis. Sci Rep. 2024;14:20386 pubmed publisher
Hammouri D, Orwick A, Doll M, Vega D, Shah P, Clarke C, et al. Remote organ cancer adversely alters renal function and induces kidney injury, inflammation, and fibrosis. bioRxiv. 2024;: pubmed publisher
Huang X, Ye L, An N, Wu C, Wu H, Li H, et al. Macrophage autophagy protects against acute kidney injury by inhibiting renal inflammation through the degradation of TARM1. Autophagy. 2024;:1-21 pubmed publisher
Biniaris Georgallis S, Aschman T, Stergioula K, Schreiber F, Jafari V, Taranko A, et al. Amplification of autoimmune organ damage by NKp46-activated ILC1s. Nature. 2024;634:952-960 pubmed publisher
Pan Y, Peng Z, Fang Z, Iddrisu L, Sun L, Deng Q, et al. A Tripeptide (Ser-Arg-Pro, SRP) from Sipunculus nudus L. Improves Cadmium-Induced Acute Kidney Injury by Targeting the MAPK, Inflammatory, and Apoptosis Pathways in Mice. Mar Drugs. 2024;22: pubmed publisher
Noonan M, Muto Y, Yoshimura Y, Leckie Harre A, Wu H, Kalinichenko V, et al. Injury-induced Foxm1 expression in the mouse kidney drives epithelial proliferation by a cyclin F-dependent mechanism. JCI Insight. 2024;9: pubmed publisher
Wang P, Ouyang J, Zhou K, Hu D, Zhang S, Zhang A, et al. Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction. Biomed J. 2024;:100730 pubmed publisher
Diaz Bulnes P, Rodr xed guez R, Bañón Maneus E, Saiz M, Bernet C, Corte Iglesias V, et al. Inhibition of BRD4 Attenuates ER Stress-induced Renal Ischemic-Reperfusion Injury. Int J Biol Sci. 2024;20:1547-1562 pubmed publisher
Vlasschaert C, Robinson Cohen C, Chen J, Akwo E, Parker A, Silver S, et al. Clonal hematopoiesis of indeterminate potential is associated with acute kidney injury. Nat Med. 2024;30:810-817 pubmed publisher
Li Z, He R, Liu J, Jin X, Jiang B, Lao Y, et al. JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway. BMC Complement Med Ther. 2024;24:101 pubmed publisher
Wu H, DIXON E, Xuanyuan Q, Guo J, Yoshimura Y, Debashish C, et al. High resolution spatial profiling of kidney injury and repair using RNA hybridization-based in situ sequencing. Nat Commun. 2024;15:1396 pubmed publisher
Wang W, Ren X, Chen X, Hong Q, Cai G. Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation. JCI Insight. 2024;9: pubmed publisher
Qu G, Li X, Jin R, Guan D, Ji J, Li S, et al. MicroRNA-26a alleviates tubulointerstitial fibrosis in diabetic kidney disease by targeting PAR4. J Cell Mol Med. 2024;28:e18099 pubmed publisher
Cai F, Li D, Xie Y, Wang X, Ma H, Xu H, et al. Sulfide:quinone oxidoreductase alleviates ferroptosis in acute kidney injury via ameliorating mitochondrial dysfunction of renal tubular epithelial cells. Redox Biol. 2024;69:102973 pubmed publisher
Jin X, He R, Lin Y, Liu J, Wang Y, Li Z, et al. Shenshuaifu Granule Attenuates Acute Kidney Injury by Inhibiting Ferroptosis Mediated by p53/SLC7A11/GPX4 Pathway. Drug Des Devel Ther. 2023;17:3363-3383 pubmed publisher
Shi L, Zha H, Pan Z, Wang J, Xia Y, Li H, et al. DUSP1 protects against ischemic acute kidney injury through stabilizing mtDNA via interaction with JNK. Cell Death Dis. 2023;14:724 pubmed publisher
Yu B, Jin L, Yao X, Zhang Y, Zhang G, Wang F, et al. TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy. Theranostics. 2023;13:4356-4375 pubmed publisher
Deng Z, Wang Y, Liu J, Zhang H, Zhou L, Zhao H, et al. WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury. Redox Biol. 2023;65:102826 pubmed publisher
Rey Serra C, Titua xf1 a J, Lin T, Herrero J, Miguel V, Barbas C, et al. Reciprocal regulation between the molecular clock and kidney injury. Life Sci Alliance. 2023;6: pubmed publisher
Vlasschaert C, Robinson Cohen C, Kestenbaum B, Silver S, Chen J, Akwo E, et al. Clonal Hematopoiesis of Indeterminate Potential is Associated with Acute Kidney Injury. medRxiv. 2023;: pubmed publisher
Hu X, Ma Z, Li S, Wen L, Huo Y, Wu G, et al. Fibroblast Growth Factor 2 Is Produced By Renal Tubular Cells to Act as a Paracrine Factor in Maladaptive Kidney Repair After Cisplatin Nephrotoxicity. Lab Invest. 2023;103:100009 pubmed publisher
Hoeft K, Schaefer G, Kim H, Schumacher D, Bleckwehl T, Long Q, et al. Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner. Cell Rep. 2023;42:112131 pubmed publisher
Zhao Z, Li G, Wang Y, Li Y, Xu H, Liu W, et al. Cytoplasmic HMGB1 induces renal tubular ferroptosis after ischemia/reperfusion. Int Immunopharmacol. 2023;116:109757 pubmed publisher
Wen L, Wei Q, Livingston M, Dong G, Li S, Hu X, et al. PFKFB3 mediates tubular cell death in cisplatin nephrotoxicity by activating CDK4. Transl Res. 2023;253:31-40 pubmed publisher
Livingston M, Shu S, Fan Y, Li Z, Jiao Q, Yin X, et al. Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis. Autophagy. 2023;19:256-277 pubmed publisher
Hallows K, Li H, Saitta B, Sepehr S, Huang P, Pham J, et al. Beneficial effects of bempedoic acid treatment in polycystic kidney disease cells and mice. Front Mol Biosci. 2022;9:1001941 pubmed publisher
Taguchi K, Elias B, Sugahara S, Sant S, Freedman B, Waikar S, et al. Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation. J Clin Invest. 2022;132: pubmed publisher
Cao X, Wang J, Zhang T, Liu Z, Liu L, Chen Y, et al. Chromatin accessibility dynamics dictate renal tubular epithelial cell response to injury. Nat Commun. 2022;13:7322 pubmed publisher
Ide S, Ide K, Abe K, Kobayashi Y, Kitai H, McKey J, et al. Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair. Cell Rep. 2022;41:111610 pubmed publisher
Zhang B, Wan S, Liu H, Qiu Q, Chen H, Chen Z, et al. Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway. Oxid Med Cell Longev. 2022;2022:5992436 pubmed publisher
McCullough K, Akhter J, Taheri M, Traylor A, Zmijewska A, Verma V, et al. Functional consequence of myeloid ferritin heavy chain on acute and chronic effects of rhabdomyolysis-induced kidney injury. Front Med (Lausanne). 2022;9:894521 pubmed publisher
Xu L, GUO J, Moledina D, Cantley L. Immune-mediated tubule atrophy promotes acute kidney injury to chronic kidney disease transition. Nat Commun. 2022;13:4892 pubmed publisher
Gohar E, Almutlaq R, Fan C, Balkawade R, Butt M, Curtis L. Does G Protein-Coupled Estrogen Receptor 1 Contribute to Cisplatin-Induced Acute Kidney Injury in Male Mice?. Int J Mol Sci. 2022;23: pubmed publisher
Dalb xf8 ge L, Christensen M, Madsen M, Secher T, Endlich N, Drenic V, et al. Nephroprotective Effects of Semaglutide as Mono- and Combination Treatment with Lisinopril in a Mouse Model of Hypertension-Accelerated Diabetic Kidney Disease. Biomedicines. 2022;10: pubmed publisher
Wang Y, Liu S, Li L, Li L, Zhou X, Wan M, et al. Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections. J Control Release. 2022;349:118-132 pubmed publisher
Wu H, Gonzalez Villalobos R, Yao X, Reilly D, Chen T, Rankin M, et al. Mapping the single-cell transcriptomic response of murine diabetic kidney disease to therapies. Cell Metab. 2022;34:1064-1078.e6 pubmed publisher
P xe9 rez Mart xed A, Ramakrishnan S, Li J, Dugourd A, Molenaar M, De La Motte L, et al. Reducing lipid bilayer stress by monounsaturated fatty acids protects renal proximal tubules in diabetes. elife. 2022;11: pubmed publisher
Kobayashi H, Davidoff O, Pujari Palmer S, Drevin M, Haase V. EPO synthesis induced by HIF-PHD inhibition is dependent on myofibroblast transdifferentiation and colocalizes with non-injured nephron segments in murine kidney fibrosis. Acta Physiol (Oxf). 2022;235:e13826 pubmed publisher
Chen X, Wu D, Wu H, Li H, Yang C, Su H, et al. Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway. Lupus Sci Med. 2022;9: pubmed publisher
Eckes T, Patyna S, Koch A, Oftring A, Gauer S, Oberm xfc ller N, et al. Sphingosine 1-Phosphate Receptor 5 (S1P5) Knockout Ameliorates Adenine-Induced Nephropathy. Int J Mol Sci. 2022;23: pubmed publisher
George B, Szilagyi J, Joy M, Aleksunes L. Regulation of renal calbindin expression during cisplatin-induced kidney injury. J Biochem Mol Toxicol. 2022;36:e23068 pubmed publisher
Yuqiang C, Lisha Z, Jiejun W, Qin X, Niansong W. Pifithrin-α ameliorates glycerol induced rhabdomyolysis and acute kidney injury by reducing p53 activation. Ren Fail. 2022;44:473-481 pubmed publisher
Shen T, Stauber J, Xu K, Jacunski A, Paragas N, Callahan M, et al. Snapshots of nascent RNA reveal cell- and stimulus-specific responses to acute kidney injury. JCI Insight. 2022;7: pubmed publisher
Telford E, Sanders A, Owen S, Ruge F, Harrison G, Jiang W, et al. Hepatitis A Virus Cellular Receptor 1 (HAVcr-1) Initiates Prostate Cancer Progression in Human Cells via Hepatocyte Growth Factor (HGF)-Induced Changes in Junctional Integrity. Biomolecules. 2022;12: pubmed publisher
Wang S, Jing K, Wu H, Li X, Yang C, Li T, et al. Activation of Transcription Factor EB Alleviates Tubular Epithelial Cell Injury via Restoring Lysosomal Homeostasis in Diabetic Nephropathy. Oxid Med Cell Longev. 2022;2022:2812493 pubmed publisher
Sasaki K, Terker A, Tang J, Cao S, Arroyo J, Niu A, et al. Macrophage interferon regulatory factor 4 deletion ameliorates aristolochic acid nephropathy via reduced migration and increased apoptosis. JCI Insight. 2022;7: pubmed publisher
An N, Yang C, Wu H, Guo Y, Huang X, Huang T, et al. Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis. Arthritis Res Ther. 2022;24:6 pubmed publisher
Kaseda R, Hosojima M, Kuwahara S, Kabasawa H, Aoki H, Higuchi Y, et al. Rice Endosperm Protein Improves the Anti-Inflammatory Effects of High-Density Lipoprotein and Produces Lower Atherosclerotic Lesion Accelerated by the Renal Mass Reduction than Casein in a Mouse Model. J Am Nutr Assoc. 2022;41:668-678 pubmed publisher
Taguchi K, Elias B, Krystofiak E, Qian S, Sant S, Yang H, et al. Quantitative super-resolution microscopy reveals promoting mitochondrial interconnectivity protects against AKI. Kidney360. 2021;2:1892-1907 pubmed publisher
Schiazza A, Considine E, Betcher M, Shepard B. Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model. Physiol Rep. 2021;9:e15007 pubmed publisher
Ma N, Wei Z, Hu J, Gu W, Ci X. Farrerol Ameliorated Cisplatin-Induced Chronic Kidney Disease Through Mitophagy Induction via Nrf2/PINK1 Pathway. Front Pharmacol. 2021;12:768700 pubmed publisher
Mulderrig L, Garaycoechea J, Tuong Z, Millington C, Dingler F, Ferdinand J, et al. Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response. Nature. 2021;600:158-163 pubmed publisher
You Y, Wu W, Huang X, Li H, Ren Y, Zeng J, et al. Deletion of Smad3 protects against C-reactive protein-induced renal fibrosis and inflammation in obstructive nephropathy. Int J Biol Sci. 2021;17:3911-3922 pubmed publisher
Ide S, Kobayashi Y, Ide K, Strausser S, Abe K, Herbek S, et al. Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair. elife. 2021;10: pubmed publisher
Lee J, Yotis D, Lee J, Sarabusky M, Shrum B, Champagne A, et al. Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma. Sci Rep. 2021;11:11840 pubmed publisher
Soranno D, Kirkbride Romeo L, Wennersten S, Ding K, Cavasin M, Baker P, et al. Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition. JACC Basic Transl Sci. 2021;6:119-133 pubmed publisher
Miguel V, Tituaña J, Herrero J, Herrero L, Serra D, Cuevas P, et al. Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis. J Clin Invest. 2021;131: pubmed publisher
Li Z, Murakoshi M, Ichikawa S, Koshida T, Adachi E, Suzuki C, et al. The sodium-glucose cotransporter 2 inhibitor tofogliflozin prevents diabetic kidney disease progression in type 2 diabetic mice. FEBS Open Bio. 2020;10:2761-2770 pubmed publisher
Yang C, Chen X, Li Z, Wu H, Jing K, Huang X, et al. SMAD3 promotes autophagy dysregulation by triggering lysosome depletion in tubular epithelial cells in diabetic nephropathy. Autophagy. 2020;:1-20 pubmed publisher
Legouis D, Ricksten S, Faivre A, Verissimo T, Gariani K, Verney C, et al. Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality. Nat Metab. 2020;2:732-743 pubmed publisher
Uni R, Inoue T, Nakamura Y, Fukaya D, Hasegawa S, Wu C, et al. Vagus nerve stimulation even after injury ameliorates cisplatin-induced nephropathy via reducing macrophage infiltration. Sci Rep. 2020;10:9472 pubmed publisher
Zaidan M, Burtin M, Zhang J, Blanc T, Barre P, Garbay S, et al. Signaling pathways predisposing to chronic kidney disease progression. JCI Insight. 2020;5: pubmed publisher
Nørgård M, Christensen M, Mutsaers H, Nørregaard R. Phenformin Attenuates Renal Injury in Unilateral Ureteral Obstructed Mice without Affecting Immune Cell Infiltration. Pharmaceutics. 2020;12: pubmed publisher
Klinkhammer B, Djudjaj S, Kunter U, Palsson R, Edvardsson V, Wiech T, et al. Cellular and Molecular Mechanisms of Kidney Injury in 2,8-Dihydroxyadenine Nephropathy. J Am Soc Nephrol. 2020;31:799-816 pubmed publisher
Liu J, Kumar S, Heinzel A, Gao M, Guo J, Alvarado G, et al. Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury. J Am Soc Nephrol. 2020;31:701-715 pubmed publisher
Yang Y, Liu S, Gao H, Wang P, Zhang Y, Zhang A, et al. Ursodeoxycholic acid protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction through acting on ALDH1L2. Free Radic Biol Med. 2020;152:821-837 pubmed publisher
Cheng S, Wu T, Li Y, Huang J, Cai T. Romidepsin (FK228) in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury is Associated with Down-Regulation of the CYP2E1 Gene. Med Sci Monit. 2020;26:e918528 pubmed publisher
Suzuki C, Tanida I, Oliva Trejo J, Kakuta S, Uchiyama Y. Autophagy Deficiency in Renal Proximal Tubular Cells Leads to an Increase in Cellular Injury and Apoptosis under Normal Fed Conditions. Int J Mol Sci. 2019;21: pubmed publisher
Chang Panesso M, Kadyrov F, Lalli M, Wu H, Ikeda S, Kefaloyianni E, et al. FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury. J Clin Invest. 2019;129:5501-5517 pubmed publisher
Bowers S, Davis Rodriguez S, Thomas Z, Rudomanova V, Bacon W, Beiersdorfer A, et al. Inhibition of fibronectin polymerization alleviates kidney injury due to ischemia-reperfusion. Am J Physiol Renal Physiol. 2019;316:F1293-F1298 pubmed publisher
Nespoux J, Patel R, Hudkins K, Huang W, Freeman B, Kim Y, et al. Gene deletion of the Na+-glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion. Am J Physiol Renal Physiol. 2019;316:F1201-F1210 pubmed publisher
Liu D, Yin Z, Huang Q, Ren Y, Li D, Wang L, et al. Exogenous biological renal support ameliorates renal pathology after ischemia reperfusion injury in elderly mice. Aging (Albany NY). 2019;11:2031-2044 pubmed publisher
Suzuki C, Tanida I, Ohmuraya M, Oliva Trejo J, Kakuta S, Sunabori T, et al. Lack of Cathepsin D in the Renal Proximal Tubular Cells Resulted in Increased Sensitivity against Renal Ischemia/Reperfusion Injury. Int J Mol Sci. 2019;20: pubmed publisher
Lazzeri E, Angelotti M, Peired A, Conte C, Marschner J, Maggi L, et al. Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury. Nat Commun. 2018;9:1344 pubmed publisher
Maydan O, McDade P, Liu Y, Wu X, Matsell D, Eddy A. Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy. Physiol Rep. 2018;6:e13654 pubmed publisher
Zhao M, Zhou Y, Liu S, Li L, Chen Y, Cheng J, et al. Control release of mitochondria-targeted antioxidant by injectable self-assembling peptide hydrogel ameliorated persistent mitochondrial dysfunction and inflammation after acute kidney injury. Drug Deliv. 2018;25:546-554 pubmed publisher
Kim Y, Park S, Manson S, Molina C, Kidd K, Thiessen Philbrook H, et al. Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease. JCI Insight. 2017;2: pubmed publisher
Tang C, Han H, Yan M, Zhu S, Liu J, Liu Z, et al. PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against Renal ischemia-reperfusion injury. Autophagy. 2017;:1-45 pubmed publisher
Liu J, Kumar S, Dolzhenko E, Alvarado G, Guo J, Lu C, et al. Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion. JCI Insight. 2017;2: pubmed publisher
Li L, Zviti R, Ha C, Wang Z, Hill J, Lin F. Forkhead box O3 (FoxO3) regulates kidney tubular autophagy following urinary tract obstruction. J Biol Chem. 2017;292:13774-13783 pubmed publisher
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Zhang Y, Li Q, Liu D, Huang Q, Cai G, Cui S, et al. GDF11 improves tubular regeneration after acute kidney injury in elderly mice. Sci Rep. 2016;6:34624 pubmed publisher
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product information
master code :
AF1817
SKU :
AF1817
product name :
Mouse TIM-1/KIM-1/HAVCR Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse TIM-1/KIM-1/HAVCR Antibody from R&D Systems is a goat polyclonal antibody to TIM-1/KIM-1/HAVCR. This antibody reacts with human,mouse,transgenic mouse. The Mouse TIM-1/KIM-1/HAVCR Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Neutralization,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
TIM-1/KIM-1/HAVCR
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse TIM-1/KIM-1/HAVCR, Tyr22-Thr212, Accession # NP_001160104
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects mouse TIM-1/KIM-1/HAVCR in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human TIM-1, recombinant mouse (rm) TIM-2, rmTIM-3, rmTIM-4, rmTIM-6, and rmTIM-7 is observed.
gene symbol :
HAVCR1
top caption :
Detection of Mouse TIM-1/KIM-1/HAVCR antibody by Western Blot.
accessionNumbers :
NP_001160104
applications :
Western Blot,Immunohistochemistry,Neutralization,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
489 USD
alt names :
CD365, HAVCR1, HAVCR-1, HAVCRT cell immunoglobin domain and mucin domain protein 1, hepatitis A virus cellular receptor 1, Kidney injury molecule 1, KIM1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIM1, TIM-1TIM, TIM1TIMD-1, TIMD1T-cell membrane protein 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.