Human LOX-1/OLR1 Antibody | R&D Systems AF1798 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human LOX-1/OLR1 Antibody

catalog :

AF1798

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 4

Reference
Florida E, Li H, Hong C, Ongstad E, Gaddipati R, Sitaula S, et al. Relationship of Soluble Lectin-Like Low-Density Lipoprotein Receptor-1 (sLOX-1) With Inflammation and Coronary Plaque Progression in Psoriasis. J Am Heart Assoc. 2023;12:e031227 pubmed publisher
Aoki Y, Dai H, Furuta F, Akamatsu T, Oshima T, Takahashi N, et al. LOX-1 mediates inflammatory activation of microglial cells through the p38-MAPK/NF-κB pathways under hypoxic-ischemic conditions. Cell Commun Signal. 2023;21:126 pubmed publisher
Sagar D, Gaddipati R, Ongstad E, Bhagroo N, An L, Wang J, et al. LOX-1: A potential driver of cardiovascular risk in SLE patients. PLoS ONE. 2020;15:e0229184 pubmed publisher
Zhao G, Hu M, Li C, Lee J, Yuan K, Zhu G, et al. Osteopontin contributes to effective neutrophil recruitment, IL-1β production and apoptosis in Aspergillus fumigatus keratitis. Immunol Cell Biol. 2018;96:401-412 pubmed publisher

product information

master code :

AF1798

SKU :

AF1798

product name :

Human LOX-1/OLR1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human LOX-1/OLR1 Antibody from R&D Systems is a goat polyclonal antibody to LOX-1/OLR1. This antibody reacts with human,porcine. The Human LOX-1/OLR1 Antibody has been validated for the following applications: Western Blot,Neutralization,ELISA Detection,Immunocytochemistry,Immunohistochemistry,Blockade of Receptor-ligand Interaction.

target :

LOX-1/OLR1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human LOX-1 (R D Systems, Catalog # 1798-LX), Ser61-Gln273, Accession # P78380

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Porcine

specificity :

Selected for its ability to block receptor-ligand interaction in a functional ELISA assay. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse LOX-1 is observed.

gene symbol :

OLR1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

Antibody validation :

Knockout/Knockdown

top caption :

LOX-1/OLR1 antibody in Human Placenta by Immunohistochemistry (IHC-P).

accessionNumbers :

P78380

applications :

Western Blot,Neutralization,ELISA Detection,Immunocytochemistry,Immunohistochemistry,Blockade of Receptor-ligand Interaction

USD :

499 USD

alt names :

CLEC8A, CLEC8ASLOX1, C-type lectin domain family 8 member A, hLOX-1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1, LOX1, LOX-1, LOX1ox LDL receptor 1, LOXIN, OLR1, oxidised low density lipoprotein (lectin-like) receptor 1, oxidized low density lipoprotein (lectin-like) receptor 1, oxidized low-density lipoprotein receptor 1, oxidized low-density lipoprotein receptor 1, soluble form, Ox-LDL receptor 1, SCARE1, scavenger receptor class E, member 1, SR-E1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage