product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Serpin E1/PAI-1 Antibody
catalog :
AF1786
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, immunohistochemistry, neutralization, immunoprecipitation, immunohistochemistry - frozen section, dot blot
more info or order :
R&D Systems product webpage
citations: 7
Reference
Annarapu G, Nolfi Donegan D, Reynolds M, Wang Y, Kohut L, Zuckerbraun B, et al. Heme stimulates platelet mitochondrial oxidant production to induce targeted granule secretion. Redox Biol. 2021;48:102205 pubmed publisher
Jeny F, Bernaudin J, Valeyre D, Kambouchner M, Pretolani M, Nunes H, et al. Hypoxia Promotes a Mixed Inflammatory-Fibrotic Macrophages Phenotype in Active Sarcoidosis. Front Immunol. 2021;12:719009 pubmed publisher
Sakamoto H, Koma Y, Higashino N, Kodama T, Tanigawa K, Shimizu M, et al. PAI-1 derived from cancer-associated fibroblasts in esophageal squamous cell carcinoma promotes the invasion of cancer cells and the migration of macrophages. Lab Invest. 2021;101:353-368 pubmed publisher
Li X, Niu N, Sun J, Mou Y, He X, Mei L. IL35 predicts prognosis in gastric cancer and is associated with angiogenesis by altering TIMP1, PAI1 and IGFBP1. FEBS Open Bio. 2020;10:2687-2701 pubmed publisher
Ferdoushi A, Li X, Griffin N, Faulkner S, Jamaluddin M, Gao F, et al. Schwann Cell Stimulation of Pancreatic Cancer Cells: A Proteomic Analysis. Front Oncol. 2020;10:1601 pubmed publisher
Kubala M, Punj V, Placencio Hickok V, Fang H, Fernandez G, Sposto R, et al. Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer. Cell Rep. 2018;25:2177-2191.e7 pubmed publisher
Zhao Y, Wang C, Wang C, Hong X, Miao J, Liao Y, et al. An essential role for Wnt/?-catenin signaling in mediating hypertensive heart disease. Sci Rep. 2018;8:8996 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1786
SKU :
AF1786
product name :
Human Serpin E1/PAI-1 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Serpin E1/PAI-1 Antibody from R&D Systems is a goat polyclonal antibody to Serpin E1/PAI-1. This antibody reacts with human,rat. The Human Serpin E1/PAI-1 Antibody has been validated for the following applications: Western Blot,Dot Blot,Neutralization,Immunohistochemistry-Frozen,Immunohistochemistry,Immunoprecipitation,Simple Western.
target :
Serpin E1/PAI-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Simple Western 2.5 ug/mL, Immunohistochemistry 5-15 ug/mL, Immunoprecipitation 25 ug/mL, Neutralization 3.5 ug/mL
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Serpin E1/PAI-1, Gly21-Pro402, Accession # P05121
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Rat
specificity :
Detects human Serpin E1/PAI-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant mouse Serpin E1 is observed.
gene symbol :
SERPINE1
top caption :
Detection of Human Serpin E1/PAI-1 antibody by Western Blot.
accessionNumbers :
P05121
applications :
Immunohistochemistry,Immunoprecipitation,Simple Western,Western Blot,Immunohistochemistry-Frozen,Dot Blot,Neutralization
USD :
489 USD
alt names :
Endothelial plasminogen activator inhibitor, Nexin, PAI1, PAI-1, PAI1PAI-1, PAISerpin E1, PLANH1, PLANH1plasminogen activator inhibitor 1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.