Human Phospho-VEGFR2/KDR/Flk-1 (Y1214) Antibody | R&D Systems AF1766 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Phospho-VEGFR2/KDR/Flk-1 (Y1214) Antibody

catalog :

AF1766

quantity :

50 ug (also 25 ug)

price :

399 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 1	Fearnley G, Smith G, Abdul Zani I, Yuldasheva N, Mughal N, Homer Vanniasinkam S, et al. VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis. Biol Open. 2016;5:571-83 pubmed publisher
	Scuruchi M, Aliqu xf2 F, Avenoso A, Mandraffino G, Vermiglio G, Minuti A, et al. Endocan Knockdown Down-Regulates the Expression of Angiogenesis-Associated Genes in Il-1ß Activated Chondrocytes. Biomolecules. 2023;13: pubmed publisher
	Xing L, Huang G, Chen R, Huang L, Liu J, Ren X, et al. Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis. J Cell Commun Signal. 2023;17:151-165 pubmed publisher
	Kouam P, Rezniczek G, Adamietz I, Buhler H. Ionizing radiation increases the endothelial permeability and the transendothelial migration of tumor cells through ADAM10-activation and subsequent degradation of VE-cadherin. BMC Cancer. 2019;19:958 pubmed publisher
	Kim D, Park J, Kim Y, Noh M, Park S, Lie E, et al. SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175. FASEB J. 2019;33:9842-9857 pubmed publisher
	Blanchard T, Czinn S, Banerjee V, Sharda N, Bafford A, Mubariz F, et al. Identification of Cross Talk between FoxM1 and RASSF1A as a Therapeutic Target of Colon Cancer. Cancers (Basel). 2019;11: pubmed publisher
	Blanchard T, Lapidus R, Banerjee V, Bafford A, Czinn S, Ahmed H, et al. Upregulation of RASSF1A in Colon Cancer by Suppression of Angiogenesis Signaling and Akt Activation. Cell Physiol Biochem. 2018;48:1259-1273 pubmed publisher
	Geng J, Wang L, Qu M, Song Y, Lin X, Chen Y, et al. Endothelial progenitor cells transplantation attenuated blood-brain barrier damage after ischemia in diabetic mice via HIF-1?. Stem Cell Res Ther. 2017;8:163 pubmed publisher
	Choi H, Lee K, Kim M, Lee K, Shin Y, Cho S, et al. DSGOST inhibits tumor growth by blocking VEGF/VEGFR2-activated angiogenesis. Oncotarget. 2016;7:21775-85 pubmed publisher

product information

master code :

AF1766

SKU :

AF1766

product name :

Human Phospho-VEGFR2/KDR/Flk-1 (Y1214) Antibody

unit size :

50 ug (also 25 ug)

description :

The Human Phospho-VEGFR2/KDR/Flk-1 (Y1214) Antibody from R&D Systems is a rabbit polyclonal antibody to VEGFR2/KDR/Flk-1. This antibody reacts with hamster,human. The Human Phospho-VEGFR2/KDR/Flk-1 (Y1214) Antibody has been validated for the following applications: Western Blot,TaqMan Protein Assay,Immunocytochemistry.

target :

VEGFR2/KDR/Flk-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Phosphopeptide containing human VEGFR2/KDR/Flk-1 Y1214 site

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Hamster,Human

specificity :

Detects human VEGFR2/KDR/Flk-1 in Western blots when phosphorylated at Y1214.

gene symbol :

KDR

top caption :

Detection of Human Phospho-VEGFR2/KDR/Flk-1 (Y1214) antibody by Western Blot.

applications :

Western Blot,TaqMan Protein Assay,Immunocytochemistry

USD :

399 USD

alt names :

CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, Flk1, Flk-1, FLK1tyrosine kinase growth factor receptor, KDR, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGF R2, VEGFR, VEGFR2, VEGFR-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage