product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat Lipocalin-2/NGAL Antibody
catalog :
AF1757
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 29
Reference
Bannier H xe9 laou xeb t M, Korving J, Ma Z, Begthel H, Giladi A, Lamers M, et al. Human conjunctiva organoids to study ocular surface homeostasis and disease. Cell Stem Cell. 2024;31:227-243.e12 pubmed publisher
Kim S, Shin M, Kim S. Lipocalin 2 activates the NLRP3 inflammasome via LPS‑induced NF‑κB signaling and plays a role as a pro‑inflammatory regulator in murine macrophages. Mol Med Rep. 2022;26: pubmed publisher
Kim S, Shin M, Seo S, Kim S. Lipocalin 2 potentially contributes to tumorigenesis from colitis via IL-6/STAT3/NF-κB signaling pathway. Biosci Rep. 2022;42: pubmed publisher
Cook L, Sengelmann M, Winkler B, Nagl C, Koch S, Schlomann U, et al. ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9. Int J Mol Sci. 2022;23: pubmed publisher
Peng K, Koduri S, Ye F, Yang J, Keep R, Xi G, et al. A timeline of oligodendrocyte death and proliferation following experimental subarachnoid hemorrhage. CNS Neurosci Ther. 2022;28:842-850 pubmed publisher
Nath K, Singh R, Grande J, Garovic V, Croatt A, Ackerman A, et al. Expression of ACE2 in the Intact and Acutely Injured Kidney. Kidney360. 2021;2:1095-1106 pubmed publisher
Yao F, Deng Y, Zhao Y, Mei Y, Zhang Y, Liu X, et al. A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis. Nat Commun. 2021;12:7333 pubmed publisher
Schiazza A, Considine E, Betcher M, Shepard B. Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model. Physiol Rep. 2021;9:e15007 pubmed publisher
Liu H, Li X, Liu J, Cui S, Liu H, Hu B, et al. miR-6869-5p Transported by Plasma Extracellular Vesicles Mediates Renal Tubule Injury and Renin-Angiotensin System Activation in Obesity. Front Med (Lausanne). 2021;8:725598 pubmed publisher
Santiago Sánchez G, Noriega Rivera R, Hernandez O Farrill E, Valiyeva F, Quiñones Diaz B, Villodre E, et al. Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021;22: pubmed publisher
Kovacevic S, Ivanov M, Zivotić M, Brkić P, Miloradovic Z, Jeremic R, et al. Immunohistochemical Analysis of 4-HNE, NGAL, and HO-1 Tissue Expression after Apocynin Treatment and HBO Preconditioning in Postischemic Acute Kidney Injury Induced in Spontaneously Hypertensive Rats. Antioxidants (Basel). 2021;10: pubmed publisher
Brockhaus J, Craveiro R, Azraq I, Niederau C, Schröder S, Weiskirchen R, et al. In Vitro Compression Model for Orthodontic Tooth Movement Modulates Human Periodontal Ligament Fibroblast Proliferation, Apoptosis and Cell Cycle. Biomolecules. 2021;11: pubmed publisher
Bannier Hélaouët M, Post Y, Korving J, Trani Bustos M, Gehart H, Begthel H, et al. Exploring the human lacrimal gland using organoids and single-cell sequencing. Cell Stem Cell. 2021;28:1221-1232.e7 pubmed publisher
Bauvois B, Pramil E, Jondreville L, Chapiro E, Quiney C, Maloum K, et al. Relation of Neutrophil Gelatinase-Associated Lipocalin Overexpression to the Resistance to Apoptosis of Tumor B Cells in Chronic Lymphocytic Leukemia. Cancers (Basel). 2020;12: pubmed publisher
Schröder S, Asimakopoulou A, Tillmann S, Koschmieder S, Weiskirchen R. TNF-α controls Lipocalin-2 expression in PC-3 prostate cancer cells. Cytokine. 2020;135:155214 pubmed publisher
Yammine L, Zablocki A, BARON W, Terzi F, Gallazzini M. Lipocalin-2 Regulates Epidermal Growth Factor Receptor Intracellular Trafficking. Cell Rep. 2019;29:2067-2077.e6 pubmed publisher
Ferrè S, Deng Y, Huen S, Lu C, Scherer P, Igarashi P, et al. Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation. Kidney Int. 2019;96:1359-1373 pubmed publisher
Joelsson J, Myszor I, Arason A, Ingthorsson S, Cherek P, Windels G, et al. Innovative in vitro method to study ventilator induced lung injury. ALTEX. 2019;36:634-642 pubmed publisher
Xu Y, Zhu Y, Jadhav K, Li Y, Sun H, Yin L, et al. Lipocalin-2 Protects Against Diet-Induced Nonalcoholic Fatty Liver Disease by Targeting Hepatocytes. Hepatol Commun. 2019;3:763-775 pubmed publisher
Miki M, Oono T, Fujimori N, Takaoka T, Kawabe K, Miyasaka Y, et al. CLEC3A, MMP7, and LCN2 as novel markers for predicting recurrence in resected G1 and G2 pancreatic neuroendocrine tumors. Cancer Med. 2019;8:3748-3760 pubmed publisher
Myszor I, Parveen Z, Ottosson H, Bergman P, Agerberth B, Stromberg R, et al. Novel aroylated phenylenediamine compounds enhance antimicrobial defense and maintain airway epithelial barrier integrity. Sci Rep. 2019;9:7114 pubmed publisher
Asimakopoulou A, Vucur M, Luedde T, Schneiders S, Kalampoka S, Weiss T, et al. Perilipin 5 and Lipocalin 2 Expression in Hepatocellular Carcinoma. Cancers (Basel). 2019;11: pubmed publisher
Musolino V, Palus S, Latouche C, Gliozzi M, Bosco F, Scarano F, et al. Cardiac expression of neutrophil gelatinase-associated lipocalin in a model of cancer cachexia-induced cardiomyopathy. ESC Heart Fail. 2019;6:89-97 pubmed publisher
Wang Z, Zhang J, Wang L, Li W, Chen L, Li J, et al. Glycine mitigates renal oxidative stress by suppressing Nox4 expression in rats with streptozotocin-induced diabetes. J Pharmacol Sci. 2018;137:387-394 pubmed publisher
Ramani K, Jawale C, Verma A, Coleman B, Kolls J, Biswas P. Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection. JCI Insight. 2018;3: pubmed publisher
Park Y, Jin Z, Jeong E, Yi C, Lee J, Park I, et al. Cilostazol attenuates kainic acid-induced hippocampal cell death. Korean J Physiol Pharmacol. 2018;22:63-70 pubmed publisher
Kang Y, Hsu W, Wu C, Hsin I, Wu P, Yeh K, et al. Metformin alleviates nickel-induced autophagy and apoptosis via inhibition of hexokinase-2, activating lipocalin-2, in human bronchial epithelial cells. Oncotarget. 2017;8:105536-105552 pubmed publisher
Haneda S, Nagaoka K, Nambo Y, Kikuchi M, Nakano Y, Li J, et al. Expression of uterine lipocalin 2 and its receptor during early- to mid-pregnancy period in mares. J Reprod Dev. 2017;63:127-133 pubmed publisher
Villalvilla A, Garcia Martin A, Largo R, Gualillo O, Herrero Beaumont G, Gomez R. The adipokine lipocalin-2 in the context of the osteoarthritic osteochondral junction. Sci Rep. 2016;6:29243 pubmed publisher
product information
master code :
AF1757
SKU :
AF1757
product name :
Human/Mouse/Rat Lipocalin-2/NGAL Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat Lipocalin-2/NGAL Antibody from R&D Systems is a goat polyclonal antibody to Lipocalin-2/NGAL. This antibody reacts with equine,human,mouse,rat. The Human/Mouse/Rat Lipocalin-2/NGAL Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.
target :
Lipocalin-2/NGAL
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived Recombinant Human Lipocalin-2/NGAL, Gln21-Gly198, Accession # P80188
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Equine,Human,Mouse,Rat
specificity :
Detects human Lipocalin-2/NGAL in direct ELISAs and Western blots.
gene symbol :
LCN2
top caption :
Detection of Human Lipocalin-2/NGAL antibody by Western Blot.
accessionNumbers :
P80188
applications :
Western Blot,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western
USD :
489 USD
alt names :
24p3, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, HNL, LCN2, lipocalin 2, lipocalin 2 (oncogene 24p3), Lipocalin2, Lipocalin-2, migration-stimulating factor inhibitor, MSFI, neutrophil gelatinase-associated lipocalin, NGAL, NGALlipocalin-2, Oncogene 24p3, p25, Siderocalin, Uterocalin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.