product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Dectin-1/CLEC7A Antibody
catalog :
AF1756
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunocytochemistry, neutralization, flow cytometry
more info or order :
citations: 5
Reference
Goldmann M, Schmidt F, Cseresny xe9 s Z, Orasch T, Jahreis S, Hartung S, et al. The Lipid Raft-Associated Protein Stomatin Is Required for Accumulation of Dectin-1 in the Phagosomal Membrane and for Full Activity of Macrophages against Aspergillus fumigatus. mSphere. 2023;8:e0052322 pubmed publisher
Hsu A, Hsieh S. Role of Dectin-1 in peripheral nerve injury. Front Cell Neurosci. 2022;16:810647 pubmed publisher
Xu F, Mu J, Teng Y, Zhang X, Sundaram K, Sriwastva M, et al. Restoring Oat Nanoparticles Mediated Brain Memory Function of Mice Fed Alcohol by Sorting Inflammatory Dectin-1 Complex Into Microglial Exosomes. Small. 2021;:e2105385 pubmed publisher
Werner G, Damme M, Schludi M, Gn xf6 rich J, Wind K, Fellerer K, et al. Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice. EMBO Rep. 2020;21:e50241 pubmed publisher
Götzl J, Brendel M, Werner G, Parhizkar S, Sebastian Monasor L, Kleinberger G, et al. Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism. EMBO Mol Med. 2019;: pubmed publisher
product information
master code :
AF1756
SKU :
AF1756
product name :
Mouse Dectin-1/CLEC7A Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse Dectin-1/CLEC7A Antibody from R&D Systems is a goat polyclonal antibody to Dectin-1/CLEC7A. This antibody reacts with mouse. The Mouse Dectin-1/CLEC7A Antibody has been validated for the following applications: Functional Assay,Western Blot,Neutralization,Immunocytochemistry,Flow Cytometry,Blockade of Receptor-ligand Interaction,CyTOF-ready.
target :
Dectin-1/CLEC7A
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Dectin-1/CLEC7A, Phe69-Leu244, Accession # Q6QLQ4
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse Dectin-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human Dectin-1 and recombinant mouse Dectin-2 alpha is observed.
gene symbol :
CLEC7A
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Yeast Dectin-1/CLEC7A by Immunocytochemistry/Immunofluorescence
accessionNumbers :
Q6QLQ4
applications :
Functional Assay,Western Blot,Neutralization,Immunocytochemistry,Flow Cytometry,Blockade of Receptor-ligand Interaction,CyTOF-ready
USD :
479 USD
alt names :
Beta-glucan receptor, BGR, CD369, CLEC7A, CLECSF12, CLECSF12DC-associated C-type lectin 1, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, dectin-1, Dectin1, DECTIN1CANDF4, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, hDectin-1, lectin-like receptor 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.