Human TIM-1/KIM-1/HAVCR Antibody | R&D Systems AF1750 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TIM-1/KIM-1/HAVCR Antibody

catalog :

AF1750

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 29

Reference
Oeyen M, Heymann C, Jacquemyn M, Daelemans D, Schols D. The Role of TIM-1 and CD300a in Zika Virus Infection Investigated with Cell-Based Electrical Impedance. Biosensors (Basel). 2024;14: pubmed publisher
Schnell J, Miao Z, Achieng M, Fausto C, Wang V, Kuyper F, et al. Stepwise developmental mimicry generates proximal-biased kidney organoids. bioRxiv. 2024;: pubmed publisher
Liu M, Zhang C, Gong X, Zhang T, Lian M, Chew E, et al. Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo. Cell Stem Cell. 2024;31:52-70.e8 pubmed publisher
Liang Z, Pan J, Xie S, Yang X, Cao R. Interaction between hTIM-1 and Envelope Protein Is Important for JEV Infection. Viruses. 2023;15: pubmed publisher
Susa K, Kobayashi K, Galichon P, Matsumoto T, Tamura A, Hiratsuka K, et al. ATP/ADP biosensor organoids for drug nephrotoxicity assessment. Front Cell Dev Biol. 2023;11:1138504 pubmed publisher
Reyes Ballista J, Miazgowicz K, Acciani M, Jimenez A, Belloli R, Havranek K, et al. Chikungunya virus entry and infectivity is primarily facilitated through cell line dependent attachment factors in mammalian and mosquito cells. Front Cell Dev Biol. 2023;11:1085913 pubmed publisher
Hattori T, Saito T, Miyamoto H, Kajihara M, Igarashi M, Takada A. Single Nucleotide Variants of the Human TIM-1 IgV Domain with Reduced Ability to Promote Viral Entry into Cells. Viruses. 2022;14: pubmed publisher
Vanslambrouck J, Wilson S, Tan K, Groenewegen E, Rudraraju R, Neil J, et al. Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids. Nat Commun. 2022;13:5943 pubmed publisher
Hiratsuka K, Miyoshi T, Kroll K, Gupta N, Valerius M, Ferrante T, et al. Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery. Sci Adv. 2022;8:eabq0866 pubmed publisher
Zheng Y, Yan R, Sun S, Kobayashi M, Xiang L, Yang R, et al. Single-cell analysis of embryoids reveals lineage diversification roadmaps of early human development. Cell Stem Cell. 2022;29:1402-1419.e8 pubmed publisher
Vanslambrouck J, Wilson S, Tan K, Groenewegen E, Rudraraju R, Neil J, et al. Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids. bioRxiv. 2022;: pubmed publisher
Gupta N, Matsumoto T, Hiratsuka K, Garcia Saiz E, Galichon P, Miyoshi T, et al. Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair. Sci Transl Med. 2022;14:eabj4772 pubmed publisher
Przepiorski A, Vanichapol T, Espiritu E, Crunk A, Parasky E, McDaniels M, et al. Modeling oxidative injury response in human kidney organoids. Stem Cell Res Ther. 2022;13:76 pubmed publisher
Zhang X, Liang C, Wang H, Guo Z, Rong H, Pan J, et al. T-Cell Immunoglobulin and Mucin Domain 1 (TIM-1) Is a Functional Entry Factor for Tick-Borne Encephalitis Virus. MBio. 2022;13:e0286021 pubmed publisher
Schmidt I, Srivastava A, Sabbisetti V, McMahon G, He J, Chen J, et al. Plasma Kidney Injury Molecule 1 in CKD: Findings From the Boston Kidney Biopsy Cohort and CRIC Studies. Am J Kidney Dis. 2022;79:231-243.e1 pubmed publisher
Xiang X, Zhu J, Zhang G, Ma Z, Livingston M, Dong Z. Proximal Tubule p53 in Cold Storage/Transplantation-Associated Kidney Injury and Renal Graft Dysfunction. Front Med (Lausanne). 2021;8:746346 pubmed publisher
Kirui J, Abidine Y, Lenman A, Islam K, Gwon Y, Lasswitz L, et al. The Phosphatidylserine Receptor TIM-1 Enhances Authentic Chikungunya Virus Cell Entry. Cells. 2021;10: pubmed publisher
Xu W, Puligandla M, Halbert B, Haas N, Flaherty K, Uzzo R, et al. Plasma KIM-1 Is Associated with Recurrence Risk after Nephrectomy for Localized Renal Cell Carcinoma: A Trial of the ECOG-ACRIN Research Group (E2805). Clin Cancer Res. 2021;27:3397-3403 pubmed publisher
Uchimura K, Wu H, Yoshimura Y, Humphreys B. Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling. Cell Rep. 2020;33:108514 pubmed publisher
Kongmanas K, Punyadee N, Wasuworawong K, Songjaeng A, Prommool T, Pewkliang Y, et al. Immortalized stem cell-derived hepatocyte-like cells: An alternative model for studying dengue pathogenesis and therapy. PLoS Negl Trop Dis. 2020;14:e0008835 pubmed publisher
Wang R, Gornalusse G, Kim Y, Pandey U, Hladik F, Vojtech L. Potent Restriction of Sexual Zika Virus Infection by the Lipid Fraction of Extracellular Vesicles in Semen. Front Microbiol. 2020;11:574054 pubmed publisher
Zhu J, Zhang G, Song Z, Xiang X, Shu S, Liu Z, et al. Protein Kinase C-δ Mediates Kidney Tubular Injury in Cold Storage-Associated Kidney Transplantation. J Am Soc Nephrol. 2020;31:1050-1065 pubmed publisher
Herrador A, Fedeli C, Radulovic E, Campbell K, Moreno H, Gerold G, et al. Dynamic Dystroglycan Complexes Mediate Cell Entry of Lassa Virus. MBio. 2019;10: pubmed publisher
Garreta E, Prado P, Tarantino C, Oria R, Fanlo L, Marti E, et al. Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells. Nat Mater. 2019;18:397-405 pubmed publisher
Niu J, Jiang Y, Xu H, Zhao C, Zhou G, Chen P, et al. TIM-1 Promotes Japanese Encephalitis Virus Entry and Infection. Viruses. 2018;10: pubmed publisher
Kumar A, Jovel J, López Orozco J, Limonta D, Airo A, Hou S, et al. Human Sertoli cells support high levels of Zika virus replication and persistence. Sci Rep. 2018;8:5477 pubmed publisher
Jin Y, Shao X, Sun B, Miao C, Li Z, Shi Y. Urinary kidney injury molecule?1 as an early diagnostic biomarker of obstructive acute kidney injury and development of a rapid detection method. Mol Med Rep. 2017;15:1229-1235 pubmed publisher
Morizane R, Bonventre J. Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells. Nat Protoc. 2017;12:195-207 pubmed publisher
Chung H, Pellegrini K, Chung J, Wanigasuriya K, Jayawardene I, Lee K, et al. Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury. PLoS ONE. 2015;10:e0133417 pubmed publisher

product information

master code :

AF1750

SKU :

AF1750

product name :

Human TIM-1/KIM-1/HAVCR Antibody

unit size :

100 ug (also 25 ug)

description :

The Human TIM-1/KIM-1/HAVCR Antibody from R&D Systems is a goat polyclonal antibody to TIM-1/KIM-1/HAVCR. This antibody reacts with human,mouse,rat,xenograft. The Human TIM-1/KIM-1/HAVCR Antibody has been validated for the following applications: ELISA Capture,Immunohistochemistry,Western Blot,Neutralization,Flow Cytometry,ELISA Development,Immunochromatography,Immunocytochemistry,ELISA Capture (Matched Antibody Pair),Dual RNAscope ISH-IHC Compatible.

target :

TIM-1/KIM-1/HAVCR

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TIM-1/KIM-1/HAVCR (R D Systems, Catalog # 1750-TM), Ser21-Thr288, Accession # Q96D42

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat,Xenograft

specificity :

Detects human TIM-1/KIM-1/HAVCR in ELISAs and Western blots.

gene symbol :

HAVCR1

top caption :

TIM-1/KIM-1/HAVCR antibody in Human Kidney Cancer Tissue by Immunohistochemistry (IHC-P).

accessionNumbers :

Q96D42

applications :

Immunohistochemistry,Western Blot,ELISA Capture,Neutralization,Flow Cytometry,ELISA Development,Immunochromatography,Immunocytochemistry,ELISA Capture (Matched Antibody Pair),Dual RNAscope ISH-IHC Compatible

USD :

509 USD

alt names :

CD365, HAVCR1, HAVCR-1, HAVCRT cell immunoglobin domain and mucin domain protein 1, hepatitis A virus cellular receptor 1, Kidney injury molecule 1, KIM1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIM1, TIM-1TIM, TIM1TIMD-1, TIMD1T-cell membrane protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage