product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TrkA Antibody
catalog :
AF175
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 2e
Wang R, Cao X, Kulej K, Liu W, Ma T, MacDonald M, et al. Uncovering BRD4 hyperphosphorylation associated with cellular transformation in NUT midline carcinoma. Proc Natl Acad Sci U S A. 2017;114:E5352-E5361 pubmed publisher
  • western blot; human; 1:200; loading ...; fig s3
Pinet S, Bessette B, Vedrenne N, Lacroix A, Richard L, Jauberteau M, et al. TrkB-containing exosomes promote the transfer of glioblastoma aggressiveness to YKL-40-inactivated glioblastoma cells. Oncotarget. 2016;7:50349-50364 pubmed publisher
Liu S, Xiang K, Yuan F, Xiang M. Generation of self-organized autonomic ganglion organoids from fibroblasts. iScience. 2023;26:106241 pubmed publisher
Viventi S, Frausin S, Howden S, Lim S, Finol Urdaneta R, McArthur J, et al. In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia. Stem Cells Transl Med. 2021;10:1157-1169 pubmed publisher
Hulme A, McArthur J, Maksour S, Miellet S, Ooi L, Adams D, et al. Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons. Front Cell Neurosci. 2020;14:600895 pubmed publisher
Castellini C, Mattioli S, Bosco A, Cotozzolo E, Cartoni Mancinelli A, Rende M, et al. Nerve growth factor receptor role on rabbit sperm storage. Theriogenology. 2020;153:54-61 pubmed publisher
Castellini C, Mattioli S, Dal Bosco A, Collodel G, Pistilli A, Stabile A, et al. In vitro effect of nerve growth factor on the main traits of rabbit sperm. Reprod Biol Endocrinol. 2019;17:93 pubmed publisher
Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, et al. Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019;26:3522-3536.e5 pubmed publisher
Alshawaf A, Viventi S, Qiu W, D Abaco G, Nayagam B, Erlichster M, et al. Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells. Sci Rep. 2018;8:603 pubmed publisher
product information
master code :
AF175
SKU :
AF175
product name :
Human TrkA Antibody
unit size :
100 ug (also 25 ug)
description :
The Human TrkA Antibody from R&D Systems is a goat polyclonal antibody to TrkA. This antibody reacts with human,rabbit. The Human TrkA Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization,Functional Assay,Immunohistochemistry,Immunocytochemistry,CyTOF-ready.
target :
TrkA
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TrkA, Ala33-Glu407, Accession # AAA36770
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Rabbit
specificity :
Detects human TrkA in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant rat TrkA is observed and 10% cross-reactivity with recombinant human (rh) TrkB and rhTrKC is observed.
gene symbol :
NTRK1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human TrkA antibody by Western Blot.
accessionNumbers :
AAA36770
applications :
Flow Cytometry,Western Blot,Neutralization,Functional Assay,Immunohistochemistry,Immunocytochemistry,CyTOF-ready
USD :
489 USD
alt names :
DKFZp781I14186, EC 2.7.10, EC 2.7.10.1, MTChigh affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, NTRK1, NTRK-1, p140-TrkA, TRK1-transforming tyrosine kinase protein, Trk-A, TRKAOncogene TRK, TRKTRK1, tyrosine kinase receptor A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.