Human Integrin ▀2/CD18 Antibody | R&D Systems AF1730 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Integrin ▀2/CD18 Antibody

catalog :

AF1730

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 11

Reference
Lin L, Nayak B, Osmulski P, Wang E, Wang C, Valente P, et al. PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms. Cell Rep. 2024;43:114527 pubmed publisher
Dos Santos J, Moreno M, Teufel L, Chilibroste S, Keating S, Groh L, et al. Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity. Cell Rep. 2024;43:113932 pubmed publisher
Stempels F, Jiang M, Warner H, Moser M, Janssens M, Maassen S, et al. Giant worm-shaped ESCRT scaffolds surround actin-independent integrin clusters. J Cell Biol. 2023;222: pubmed publisher
Belkahla S, Brualla J, Fayd Herbe De Maudave A, Falvo P, Allende Vega N, Constantinides M, et al. The metabolism of cells regulates their sensitivity to NK cells depending on p53 status. Sci Rep. 2022;12:3234 pubmed publisher
Allende Vega N, Marco Brualla J, Falvo P, Alexia C, Constantinides M, De Maudave A, et al. Metformin sensitizes leukemic cells to cytotoxic lymphocytes by increasing expression of intercellular adhesion molecule-1 (ICAM-1). Sci Rep. 2022;12:1341 pubmed publisher
Davies S, Reynolds G, Wilkinson A, Li X, Rose R, Leekha M, et al. Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process. Cell Rep. 2019;29:1610-1620.e4 pubmed publisher
Ristow L, Tran V, Schwartz K, Pankratz L, Mehle A, Sauer J, et al. The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity. MBio. 2019;10: pubmed publisher
Blatchley M, Hall F, Wang S, Pruitt H, Gerecht S. Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis. Sci Adv. 2019;5:eaau7518 pubmed publisher
Benson B, Li L, Myers J, Dorand R, Gurkan U, Huang A, et al. Biomimetic post-capillary venule expansions for leukocyte adhesion studies. Sci Rep. 2018;8:9328 pubmed publisher
Lavoie S, Dumas E, Vulesevic B, Neagoe P, White M, Sirois M. Synthesis of Human Neutrophil Extracellular Traps Contributes to Angiopoietin-Mediated In Vitro Proinflammatory and Proangiogenic Activities. J Immunol. 2018;200:3801-3813 pubmed publisher
Zhou X, Zhao R, Schwarz K, Mangeat M, Schwarz E, Hamed M, et al. Bystander cells enhance NK cytotoxic efficiency by reducing search time. Sci Rep. 2017;7:44357 pubmed publisher

product information

master code :

AF1730

SKU :

AF1730

product name :

Human Integrin ▀2/CD18 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Integrin ß2/CD18 Antibody from R&D Systems is a goat polyclonal antibody to Integrin beta 2/CD18. This antibody reacts with human. The Human Integrin ß2/CD18 Antibody has been validated for the following applications: Flow Cytometry,Functional Assay,Migration Assay,Western Blot,Neutralization,Immunofluorescence,Immunocytochemistry,Adhesion Blockade,CyTOF-ready.

target :

Integrin beta 2/CD18

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Integrin ▀2, Gln23-Asn700, Accession # AAA59490

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human Integrin ▀2 in direct ELISAs and Western blots.

gene symbol :

ITGB2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Integrin ss2/CD18 antibody in Human PBMCs by Immunocytochemistry (ICC).

accessionNumbers :

AAA59490

applications :

Flow Cytometry,Functional Assay,Migration Assay,Western Blot,Neutralization,Immunofluorescence,Immunocytochemistry,Adhesion Blockade,CyTOF-ready

USD :

509 USD

alt names :

959 beta subunit precursor)10, CD18, CD18 antigen, CD18beta 2, cell surface adhesion glycoprotein (LFA-1, CR3, integrin beta-2, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1;macrophage antigen 1 (mac-1) beta subunit), integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), ITGB2, LAD, LCAMB, leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C, LFA-1, LFA-1 beta, MAC-1 beta, MF17, MFI7, P150, p150,95 beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage