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company name :
R&D Systems
product type :
antibody
product name :
Human IL-23 p19 Antibody
catalog :
AF1716
quantity :
50 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, neutralization, immunohistochemistry - frozen section
more info or order :
citations: 3
Reference
Gringhuis S, Kaptein T, Remmerswaal E, Drewniak A, Wevers B, Theelen B, et al. Fungal sensing by dectin-1 directs the non-pathogenic polarization of TH17 cells through balanced type I IFN responses in human DCs. Nat Immunol. 2022;23:1735-1748 pubmed publisher
Fukasawa T, Yoshizaki A, Ebata S, Yoshizaki Ogawa A, Asano Y, Enomoto A, et al. Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model. elife. 2021;10: pubmed publisher
Li J, Cheng L, Jia H, Liu C, Wang S, Liu Y, et al. IFN-γ facilitates liver fibrogenesis by CD161+CD4+ T cells through a regenerative IL-23/IL-17 axis in chronic hepatitis B virus infection. Clin Transl Immunology. 2021;10:e1353 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1716
SKU :
AF1716
product name :
Human IL-23 p19 Antibody
unit size :
50 ug (also 25 ug)
seo description :
The Human IL-23 p19 Antibody from R&D Systems is a goat polyclonal antibody to IL-23A/IL-23 P19. This antibody reacts with human. The Human IL-23 p19 Antibody has been validated for the following applications: ELISA Development,Neutralization,Immunohistochemistry-Frozen,Western Blot.
target :
IL-23
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Neutralization 0.2-0.8 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human IL-23 p19, Arg20-Pro189, Accession # AAG37232
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human IL-23 p19 in direct ELISA and Western blot. In direct ELISA, approximately 50% cross-reactivity with recombinant canine IL-23p19, less then 25% cross-reactivity with recombinant feline IL-23p19, less than 5% cross-reactivity with recombinant mouse IL-23p19, recombinant human IL-12p40, and recombinant rat IL-23p40 is observed.
gene symbol :
IL23A
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
IL-17 Secretion Induced by IL-23 and Neutralization by Human IL-23 Antibody.
accessionNumbers :
AAG37232
applications :
Western Blot,ELISA Development,Immunohistochemistry-Frozen,Neutralization
USD :
499 USD
alt names :
IL23, IL-23, IL-23 p19, IL-23 p19/IL-12 p40, IL23A, IL-23A, IL-23-A, IL-23p19, IL-23p19/IL-12p40, IL23P19P19, interleukin 23 p19 subunit, interleukin 23, alpha subunit p19, interleukin-23 subunit alpha, Interleukin-23 subunit p19, JKA3 induced upon T-cell activation, MGC79388, SGRF, SGRFIL-23 subunit alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.