product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat HSP70/HSPA1A Antibody
catalog :
AF1663
quantity :
50 ug (also 25 ug)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 12
Reference
Pizzolato G, Moparthi L, Pagella P, Cant xf9 C, D Arcy P, Koch S. The tumor suppressor p53 is a negative regulator of the carcinoma-associated transcription factor FOXQ1. J Biol Chem. 2024;300:107126 pubmed publisher
Li J, Jaiswal M, Chien J, Kozlenkov A, Jung J, Zhou P, et al. Divergent single cell transcriptome and epigenome alterations in ALS and FTD patients with C9orf72 mutation. Nat Commun. 2023;14:5714 pubmed publisher
Moparthi L, Koch S. FOX transcription factors are common regulators of Wnt/β-catenin-dependent gene transcription. J Biol Chem. 2023;299:104667 pubmed publisher
Pizzolato G, Moparthi L, S xf6 derholm S, Cant xf9 C, Koch S. The oncogenic transcription factor FOXQ1 is a differential regulator of Wnt target genes. J Cell Sci. 2022;135: pubmed publisher
Mart xed nez L, Lensing S, Chang D, Magpantay L, Mitsuyasu R, Ambinder R, et al. Plasma extracellular vesicles bearing PD-L1, CD40, CD40L or TNF-RII are significantly reduced after treatment of AIDS-NHL. Sci Rep. 2022;12:9185 pubmed publisher
Clabough E, Ingersoll J, Reekes T, Gleichsner A, Ryan A. Acute Ethanol Exposure during Synaptogenesis Rapidly Alters Medium Spiny Neuron Morphology and Synaptic Protein Expression in the Dorsal Striatum. Int J Mol Sci. 2021;23: pubmed publisher
Lyu Y, Kopcho S, Mohan M, Okeoma C. Long-Term Low-Dose Delta-9-Tetrahydrocannbinol (THC) Administration to Simian Immunodeficiency Virus (SIV) Infected Rhesus Macaques Stimulates the Release of Bioactive Blood Extracellular Vesicles (EVs) that Induce Divergent Structural Adaptations an. Cells. 2020;9: pubmed publisher
Solga R, Behrens J, Ziemann A, Riou A, Berwanger C, Becker L, et al. CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells. Eur J Cell Biol. 2019;98:151046 pubmed publisher
Gerber H, Mosser S, Boury Jamot B, Stumpe M, Piersigilli A, Goepfert C, et al. The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease. Acta Neuropathol Commun. 2019;7:13 pubmed publisher
Son Y, Kim H, Choi W, Chun C, Chun J. RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family. Nat Commun. 2019;10:77 pubmed publisher
Cao Y, Zhu X, Hossen M, Kakar P, Zhao Y, Chen X. Augmentation of vaccine-induced humoral and cellular immunity by a physical radiofrequency adjuvant. Nat Commun. 2018;9:3695 pubmed publisher
Lu Z, Casalino Matsuda S, Nair A, Buchbinder A, Budinger G, Sporn P, et al. A role for heat shock factor 1 in hypercapnia-induced inhibition of inflammatory cytokine expression. FASEB J. 2018;32:3614-3622 pubmed publisher
product information
master code :
AF1663
SKU :
AF1663
product name :
Human/Mouse/Rat HSP70/HSPA1A Antibody
unit size :
50 ug (also 25 ug)
description :
The Human/Mouse/Rat HSP70/HSPA1A Antibody from R&D Systems is a rabbit polyclonal antibody to HSP70/HSPA1A. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat HSP70/HSPA1A Antibody has been validated for the following applications: Western Blot,Simple Western,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
HSP70/HSPA1A
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rabbit
immunogen :
E. coli -derived recombinant human HSP70, Met1-Asp641, Accession # P08107
isotype :
IgG
purity :
Antigen and protein A Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects the induced form of recombinant endogenous human, mouse and rat HSP70/HSPA1A (HSP72) in Western blots. In Western blots, no cross-reactivity with the constitutively expressed HSC70 (HSP73) is detected.
gene symbol :
HSPA1A
Antibody validation :
Biological Validation
top caption :
Detection of Human, Mouse, and Rat HSP70/HSPA1A antibody by Western Blot.
accessionNumbers :
P08107
applications :
Western Blot,Simple Western,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
399 USD
alt names :
dnaK-type molecular chaperone HSP70-1, FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, Heat shock 70 kDa protein 1/2, heat shock 70 kDa protein 1A/1B, heat shock 70kD protein 1A, heat shock 70kDa protein 1A, heat shock-induced protein, HSP70.1/HSP70.2, HSP70-1, HSP70-1/HSP70-2, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1A, HSPA1B
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.