Human/Mouse/Rat Phospho-ATM (S1981) Antibody | R&D Systems AF1655 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat Phospho-ATM (S1981) Antibody

catalog :

AF1655

quantity :

100 ug (also 25 ug)

price :

429 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 4c	Qiao F, Law H, Krieger K, Clement E, Xiao Y, Buckley S, et al. Ctdp1 deficiency leads to early embryonic lethality in mice and defects in cell cycle progression in MEFs. Biol Open. 2021;10: pubmed publisher
	Serey Gaut M, Cortés M, Makrythanasis P, Suri M, Taylor A, Sullivan J, et al. Bi-allelic TTI1 variants cause an autosomal-recessive neurodevelopmental disorder with microcephaly. Am J Hum Genet. 2023;110:499-515 pubmed publisher
	Zeng F, Parker K, Zhan Y, Miller M, Zhu M. Upregulated DNA Damage-Linked Biomarkers in Parkinson's Disease Model Mice. ASN Neuro. 2023;15:17590914231152099 pubmed publisher
	Guo Y, Chomiak A, Hong Y, Lowe C, Kopsidas C, Chan W, et al. Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration. iScience. 2022;25:104519 pubmed publisher
	Magni M, Paolizzi C, Monfrini C, Vella C, Corradini P, Carniti C. Targeting the DNA Damage Response to Increase Anthracycline-Based Chemotherapy Cytotoxicity in T-Cell Lymphoma. Int J Mol Sci. 2022;23: pubmed publisher
	Blanchard Rohner G, Peirolo A, Coulon L, Korff C, Horvath J, Burkhard P, et al. Childhood-Onset Movement Disorders Can Mask a Primary Immunodeficiency: 6 Cases of Classical Ataxia-Telangiectasia and Variant Forms. Front Immunol. 2022;13:791522 pubmed publisher
	Abu Libdeh B, Jhujh S, Dhar S, Sommers J, Datta A, Longo G, et al. RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1. J Clin Invest. 2022;132: pubmed publisher
	Pal S, Nixon B, Glennon M, Shridhar P, Satterfield S, Su Y, et al. Replication Stress Response Modifies Sarcomeric Cardiomyopathy Remodeling. J Am Heart Assoc. 2021;10:e021768 pubmed publisher
	Blakemore D, Vilaplana Lopera N, Almaghrabi R, Gonzalez E, Moya M, Ward C, et al. MYBL2 and ATM suppress replication stress in pluripotent stem cells. EMBO Rep. 2021;22:e51120 pubmed publisher
	Park S, Kang N, Song E, Wie M, Lee E, Hwang S, et al. ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress. Nat Commun. 2019;10:5718 pubmed publisher
	Hu W, Krieger K, Lagundzin D, Li X, Cheung R, Taniguchi T, et al. CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI. Cell Death Discov. 2019;5:105 pubmed publisher
	Lee J, Mand M, Kao C, Zhou Y, Ryu S, Richards A, et al. ATM directs DNA damage responses and proteostasis via genetically separable pathways. Sci Signal. 2018;11: pubmed publisher
	Smith E, Gole B, Willis N, Soria R, Starnes L, Krumpelbeck E, et al. DEK is required for homologous recombination repair of DNA breaks. Sci Rep. 2017;7:44662 pubmed publisher
	Clarke T, Sanchez Bailon M, Chiang K, Reynolds J, Herrero Ruiz J, Bandeiras T, et al. PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination. Mol Cell. 2017;65:900-916.e7 pubmed publisher
	Enriquez Rios V, Dumitrache L, Downing S, Li Y, Brown E, Russell H, et al. DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis. J Neurosci. 2017;37:893-905 pubmed publisher

product information

brand :

R&D Systems

master code :

AF1655

SKU :

AF1655

product name :

Human/Mouse/Rat Phospho-ATM (S1981) Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Rat Phospho-ATM (S1981) Antibody from R&D Systems is a rabbit polyclonal antibody to ATM. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat Phospho-ATM (S1981) Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Bioassay,Immunohistochemistry-Paraffin,Simple Western.

target :

ATM

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Simple Western 10 ug/mL

host :

Rabbit

immunogen :

Phosphopeptide containing human ATM S1981 site

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human ATM when phosphorylated at S1981. Also detects the comparable phosphorylated sites in mouse ATM (S1987) and rat ATM (S1952).

gene symbol :

ATM

top caption :

Detection of Human/Mouse/Rat Phospho-ATM (S1981) antibody by Western Blot.

applications :

Simple Western,Bioassay,Western Blot,Immunohistochemistry-Paraffin

USD :

429 USD

alt names :

AT mutated, A-T mutated, AT1, ATA, ataxia telangiectasia mutated, ataxia telangiectasia mutated (includes complementation groups A, C and D), ATC, ATD, ATDC, ATE, ATM serine/threonine kinase, DKFZp781A0353, EC 2.7.11.1, MGC74674, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1, TPLL

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage