Human/Mouse Caspase-8 Antibody | R&D Systems AF1650 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse Caspase-8 Antibody

catalog :

AF1650

quantity :

100 ug (also 25 ug)

price :

419 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 8

Reference
Marino Merlo F, Klett A, Papaianni E, Drago S, Macchi B, Rinc xf3 n M, et al. Caspase-8 is required for HSV-1-induced apoptosis and promotes effective viral particle release via autophagy inhibition. Cell Death Differ. 2022;: pubmed publisher
Gu L, Surolia R, Larson Casey J, He C, Davis D, Kang J, et al. Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling. Cell Death Differ. 2022;29:118-132 pubmed publisher
Kusakabe J, Hata K, Miyauchi H, Tajima T, Wang Y, Tamaki I, et al. Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models. Cell Mol Gastroenterol Hepatol. 2021;11:1351-1367 pubmed publisher
Chen T, Dai X, Dai J, Ding C, Zhang Z, Lin Z, et al. AFP promotes HCC progression by suppressing the HuR-mediated Fas/FADD apoptotic pathway. Cell Death Dis. 2020;11:822 pubmed publisher
Rogers C, Erkes D, Nardone A, Aplin A, Fernandes Alnemri T, Alnemri E. Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation. Nat Commun. 2019;10:1689 pubmed publisher
Leznicki P, Natarajan J, Bader G, Spevak W, Schlattl A, Abdul Rehman S, et al. Expansion of DUB functionality generated by alternative isoforms - USP35, a case study. J Cell Sci. 2018;131: pubmed publisher
Ijiri M, Fujiya M, Konishi H, Tanaka H, Ueno N, Kashima S, et al. Ferrichrome identified from Lactobacillus casei ATCC334 induces apoptosis through its iron-binding site in gastric cancer cells. Tumour Biol. 2017;39:1010428317711311 pubmed publisher
Khan T, Wender P, Alkon D. Bryostatin and its synthetic analog, picolog rescue dermal fibroblasts from prolonged stress and contribute to survival and rejuvenation of human skin equivalents. J Cell Physiol. 2018;233:1523-1534 pubmed publisher

product information

master code :

AF1650

SKU :

AF1650

product name :

Human/Mouse Caspase-8 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse Caspase-8 Antibody from R&D Systems is a rabbit polyclonal antibody to Caspase-8. This antibody reacts with complex species category,human,mouse,xenograft. The Human/Mouse Caspase-8 Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry,Simple Western.

target :

Caspase-8

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rabbit

immunogen :

E. coli -derived recombinant human Caspase-8, Ser217-Asp384 (Asp285His) (p18 subunit), Leu385-Asp479 (p10 subunit), Accession # Q14790

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Complex Species Category,Human,Mouse,Xenograft

specificity :

Detects human/mouse Caspase-8 and cleavage products. Detects multiple isoforms of Caspase-8.

gene symbol :

CASP8

top caption :

Detection of Human Caspase-8 antibody by Western Blot.

accessionNumbers :

Q14790

applications :

Western Blot,Neutralization,Immunohistochemistry,Simple Western

USD :

419 USD

alt names :

AIS, androgen receptor, CASP8, Caspase8, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, Mch5, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage