product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat ERK1/ERK2 Antibody
catalog :
AF1576
quantity :
100 ug (also 25 ug)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 3d
Matlac D, Hadrava Vanova K, Bechmann N, Richter S, Folberth J, Ghayee H, et al. Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas. Front Endocrinol (Lausanne). 2021;12:589451 pubmed publisher
Hong Y, Kim G, Park Y, Jo H, Nam M, Kim D, et al. Suaeda glauca Attenuates Liver Fibrosis in Mice by Inhibiting TGFβ1-Smad2/3 Signaling in Hepatic Stellate Cells. Nutrients. 2023;15: pubmed publisher
Liang Z, Zhang Z, Zhang Q, Dong X, Yang X, Zhang J, et al. The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance. iScience. 2022;25:105233 pubmed publisher
Okada M, Fukuyama K, Motomura E. Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of Quetiapine. Int J Mol Sci. 2022;23: pubmed publisher
Fukuyama K, Motomura E, Okada M. Brexpiprazole Reduces 5-HT7 Receptor Function on Astroglial Transmission Systems. Int J Mol Sci. 2022;23: pubmed publisher
Fukuyama K, Okada M. Brivaracetam and Levetiracetam Suppress Astroglial L-Glutamate Release through Hemichannel via Inhibition of Synaptic Vesicle Protein. Int J Mol Sci. 2022;23: pubmed publisher
Shiroyama T, Fukuyama K, Okada M. Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43. Int J Mol Sci. 2021;22: pubmed publisher
Massman L, Pereckas M, Zwagerman N, Olivier Van Stichelen S. O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells. Endocrinology. 2021;162: pubmed publisher
Liu S, An G, Cao Q, Li T, Jia X, Lei L. The miR-106b/NR2F2-AS1/PLEKHO2 Axis Regulates Migration and Invasion of Colorectal Cancer through the MAPK Pathway. Int J Mol Sci. 2021;22: pubmed publisher
Ungefroren H, Christl J, Eiden C, Wellner U, Lehnert H, Marquardt J. Autocrine TGFβ1 Opposes Exogenous TGFβ1-Induced Cell Migration and Growth Arrest through Sustainment of a Feed-Forward Loop Involving MEK-ERK Signaling. Cancers (Basel). 2021;13: pubmed publisher
Chen M, Ramesha S, Weinstock L, Gao T, Ping L, Xiao H, et al. Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease. J Neurosci Res. 2021;99:1704-1721 pubmed publisher
Rao L, Wang Y, Zhang L, Wu G, Zhang L, Wang F, et al. IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages. Cell Death Differ. 2021;28:1270-1283 pubmed publisher
Fukuyama K, Okada M. Age-Dependent and Sleep/Seizure-Induced Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy. Int J Mol Sci. 2020;21: pubmed publisher
Liu J, Liu J, Bai M, Wang H. Protective effect of puerarin against burn-induced heart injury in rats. Exp Ther Med. 2020;20:275-282 pubmed publisher
Barroso Chinea P, Luis Ravelo D, Fumagallo Reading F, Castro Hernandez J, Salas Hernandez J, Rodríguez Núñez J, et al. DRD3 (dopamine receptor D3) but not DRD2 activates autophagy through MTORC1 inhibition preserving protein synthesis. Autophagy. 2020;16:1279-1295 pubmed publisher
Fang Z, Li C, Li S. MicroRNA-193b acts as a tumor suppressor in colon cancer progression via targeting RAB22A. Exp Ther Med. 2019;17:3921-3928 pubmed publisher
Herbrich S, Kannan S, Nolo R, Hornbaker M, Chandra J, Zweidler McKay P. Characterization of TRKA signaling in acute myeloid leukemia. Oncotarget. 2018;9:30092-30105 pubmed publisher
Joo M, Jang C, Park J, Choi S, Ro S, Kim M, et al. Effect of electrical stimulation on neural regeneration via the p38-RhoA and ERK1/2-Bcl-2 pathways in spinal cord-injured rats. Neural Regen Res. 2018;13:340-346 pubmed publisher
Ungefroren H, Witte D, Fiedler C, Gädeken T, Kaufmann R, Lehnert H, et al. The Role of PAR2 in TGF-?1-Induced ERK Activation and Cell Motility. Int J Mol Sci. 2017;18: pubmed publisher
Witte D, Otterbein H, Förster M, Giehl K, Zeiser R, Lehnert H, et al. Negative regulation of TGF-β1-induced MKK6-p38 and MEK-ERK signalling and epithelial-mesenchymal transition by Rac1b. Sci Rep. 2017;7:17313 pubmed publisher
Rodrigues B, Muñoz V, Kuga G, Gaspar R, Nakandakari S, Crisol B, et al. Obesity Increases Mitogen-Activated Protein Kinase Phosphatase-3 Levels in the Hypothalamus of Mice. Front Cell Neurosci. 2017;11:313 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1576
SKU :
AF1576
product name :
Human/Mouse/Rat ERK1/ERK2 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat ERK1/ERK2 Antibody from R&D Systems is a rabbit polyclonal antibody to ERK1/ERK2. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat ERK1/ERK2 Antibody has been validated for the following applications: Western Blot,Simple Western,Immunohistochemistry.
target :
ERK1/ERK2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.2 ug/mL, Simple Western 10 ug/mL
host :
Rabbit
immunogen :
E. coli -derived recombinant human ERK1/ERK2, XM_055766 and NM_138957, respectively
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human, mouse and rat ERK1/ERK2.
top caption :
Detection of Human/Mouse/Rat ERK1/ERK2 antibody by Western Blot.
applications :
Immunohistochemistry,Western Blot,Simple Western
USD :
409 USD
alt names :
ERK1, ERK-1, ERT1, ERT2, Extracellular signal-regulated kinase 1, extracellular signal-related kinase 1, HS44KDAP, HUMKER1A, Insulin-stimulated MAP2 kinase, MAPK 1, MAPK1, MAPK2, MAPK3, Microtubule-associated protein 2 kinase, mitogen-activated protein kinase 3, p41mapk, p42mapk, p44erk1, p44-ERK1, p44mapk, p44-MAPK, PRKM1, PRKM2, PRKM3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.