Mouse LOX-1/OLR1 Antibody | R&D Systems AF1564 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse LOX-1/OLR1 Antibody

catalog :

AF1564

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, neutralization

more info or order :

R&D Systems product webpage

citations: 8

Reference
Borges T, Lima K, Murshid A, Lape I, Zhao Y, Rigo M, et al. Innate extracellular Hsp70 inflammatory properties are mediated by the interaction of Siglec-E and LOX-1 receptors. bioRxiv. 2023;: pubmed publisher
Reyes C, Nova Lamperti E, Duran Sandoval D, Rojas D, Gajardo J, Guzman Gutierrez E, et al. Loxin Reduced the Inflammatory Response in the Liver and the Aortic Fatty Streak Formation in Mice Fed with a High-Fat Diet. Int J Mol Sci. 2022;23: pubmed publisher
Korbelik M. Optimization of Whole Tumor Cell Vaccines by Interaction with Phagocytic Receptors. Vaccines (Basel). 2021;9: pubmed publisher
Kitaura A, Nishinaka T, Hamasaki S, Hatipoglu O, Wake H, Nishibori M, et al. Advanced glycation end-products reduce lipopolysaccharide uptake by macrophages. PLoS ONE. 2021;16:e0245957 pubmed publisher
Yan L, Jia Q, Cao H, Chen C, Xing S, Huang Y, et al. Fisetin ameliorates atherosclerosis by regulating PCSK9 and LOX-1 in apoE-/- mice. Exp Ther Med. 2021;21:25 pubmed publisher
Koga M, Kanaoka Y, Inada K, Omine S, Kataoka Y, Yamauchi A. Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages. J Pharmacol Sci. 2020;143:106-111 pubmed publisher
Mentrup T, Theodorou K, Cabrera Cabrera F, Helbig A, Happ K, Gijbels M, et al. Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis. J Exp Med. 2019;: pubmed publisher
Yu L, Lai C, Lee C, Wang J. Highly electronegative low-density lipoprotein L5 evokes microglial activation and creates a neuroinflammatory stress via Toll-like receptor 4 signaling. J Neurochem. 2017;142:231-245 pubmed publisher

product information

master code :

AF1564

SKU :

AF1564

product name :

Mouse LOX-1/OLR1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse LOX-1/OLR1 Antibody from R&D Systems is a goat polyclonal antibody to LOX-1/OLR1. This antibody reacts with mouse,n/a,rat. The Mouse LOX-1/OLR1 Antibody has been validated for the following applications: Blocking,Western Blot,Neutralization,Blockade of Receptor-ligand Interaction.

target :

LOX-1/OLR1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse LOX-1 (R D Systems, Catalog # 1564-LX), Arg60-Ile363, Accession # AAG44998

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,N/A,Rat

specificity :

Selected for its ability to block receptor-ligand interaction in a functional ELISA assay. In Western blots, approximately 5% cross-reactivity with recombinant human LOX-1 is observed.

gene symbol :

OLR1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

AAG44998

applications :

Blocking,Western Blot,Neutralization,Blockade of Receptor-ligand Interaction

USD :

489 USD

alt names :

CLEC8A, CLEC8ASLOX1, C-type lectin domain family 8 member A, hLOX-1, Lectin-like oxidized LDL receptor 1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1, LOX1, LOX-1, LOX1ox LDL receptor 1, LOXIN, OLR1, oxidised low density lipoprotein (lectin-like) receptor 1, oxidized low density lipoprotein (lectin-like) receptor 1, oxidized low-density lipoprotein receptor 1, oxidized low-density lipoprotein receptor 1, soluble form, Ox-LDL receptor 1, SCARE1, scavenger receptor class E, member 1, SR-E1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage