product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human PDGF-C Antibody
catalog :
AF1560
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, neutralization, immunohistochemistry - frozen section
more info or order :
citations: 2
Reference
Akiyama T, Yasuda T, Uchihara T, Yasuda Yoshihara N, Tan B, Yonemura A, et al. Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic Tumors. Cancer Res. 2023;83:753-770 pubmed publisher
Zheng L, Zhao C, Du Y, Lin X, Jiang Y, Lee C, et al. PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently. Oncotarget. 2016;7:77902-77915 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1560
SKU :
AF1560
product name :
Human PDGF-C Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human PDGF-C Antibody from R&D Systems is a goat polyclonal antibody to PDGF-C. This antibody reacts with human. The Human PDGF-C Antibody has been validated for the following applications: Western Blot,Neutralization,Functional Assay,Immunohistochemistry,Immunohistochemistry-Frozen.
target :
PDGF-C
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 6-24 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human PDGF-C, Gly230-Gly345, Accession # Q9NRA1
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human PDGF-C in direct ELISAs and Western blots. In Western blots, approximately 15% cross-reactivity with recombinant mouse PDGF-C is observed, and less than 1% cross-reactivity with human PDGF, recombinant human (rh) PDGF-AA, rhPDGF-BB, rhPDGF-AB, and rhPDGF-D is observed.
gene symbol :
PDGFC
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human PDGF-C antibody by Western Blot.
accessionNumbers :
Q9NRA1
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization,Functional Assay
USD :
469 USD
alt names :
FALLOTEIN, PDGFC, PDGF-C, platelet derived growth factor C, platelet-derived growth factor C, SCDGFSpinal cord-derived growth factor, secretory growth factor-like protein, VEGF-E
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.