product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Podocalyxin Antibody
catalog :
AF1556
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 67
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s7a
Nam J, Kim A, Choi S, Kim J, Choi K, Cho S, et al. An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage. Nat Commun. 2021;12:3279 pubmed publisher
  • immunohistochemistry; mouse; 1:300; loading ...; fig s5a
Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, et al. Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021;148: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s2a
Zarb Y, Sridhar S, Nassiri S, Utz S, Schaffenrath J, Maheshwari U, et al. Microglia control small vessel calcification via TREM2. Sci Adv. 2021;7: pubmed publisher
Janes P, Parslow A, Cao D, Rigopoulos A, Lee F, Gong S, et al. An Anti-VEGF-B Antibody Reduces Abnormal Tumor Vasculature and Enhances the Effects of Chemotherapy. Cancers (Basel). 2024;16: pubmed publisher
Niasse A, Louis K, Lenoir O, Schwarz C, Xu X, Couturier A, et al. Protective Role of the Podocyte IL-15 / STAT5 Pathway in Focal Segmental Glomerulosclerosis. Kidney Int Rep. 2024;9:1093-1106 pubmed publisher
Schanz M, Kimmel M, Alscher M, Amann K, Daniel C. TIMP-2 and IGFBP7 in human kidney biopsies in renal disease. Clin Kidney J. 2023;16:1434-1446 pubmed publisher
Cornuault L, H xe9 rion F, Bourguignon C, Rouault P, Foussard N, Alzieu P, et al. Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction. J Am Heart Assoc. 2023;12:e029279 pubmed publisher
Chen Y, Chauhan S, Gong C, Dayton H, Xu C, De La Cruz E, et al. Scalable projected Light Sheet Microscopy for high-resolution imaging of living and cleared samples. bioRxiv. 2023;: pubmed publisher
Chen X, Wolfe D, Bindu D, Zhang M, Taskin N, Goertsen D, et al. Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Nat Commun. 2023;14:3345 pubmed publisher
Liang S, Wang Y, Kang M, Deng J, Chen L, Hong X, et al. Generation and characterization of an inducible renal proximal tubule-specific CreERT2 mouse. Front Cell Dev Biol. 2023;11:1171637 pubmed publisher
Paavonsalo S, Subashi Y, Lackman M, Karaman S. Whole-mount immunofluorescence staining of blood and lymphatic vessels in murine small intestine. STAR Protoc. 2023;4:102310 pubmed publisher
Chen X, Wolfe D, Bindu D, Zhang M, Taskin N, Goertsen D, et al. Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. bioRxiv. 2023;: pubmed publisher
Stobart J, Erlebach E, Gl xfc ck C, Huang S, Barrett M, Li M, et al. Altered hemodynamics and vascular reactivity in a mouse model with severe pericyte deficiency. J Cereb Blood Flow Metab. 2023;43:763-777 pubmed publisher
Zaitoun I, Song Y, Zaitoun H, Sorenson C, Sheibani N. Assessment of Choroidal Vasculature and Innate Immune Cells in the Eyes of Albino and Pigmented Mice. Cells. 2022;11: pubmed publisher
Gilln xe4 s S, Gallini R, He L, Betsholtz C, Andrae J. Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development. Biol Open. 2022;11: pubmed publisher
Jacob L, de Brito Neto J, Lenck S, Corcy C, Benbelkacem F, Geraldo L, et al. Conserved meningeal lymphatic drainage circuits in mice and humans. J Exp Med. 2022;219: pubmed publisher
Baluk P, McDonald D. Imaging Blood Vessels and Lymphatics in Mouse Trachea Wholemounts. Methods Mol Biol. 2022;2441:115-134 pubmed publisher
Karaman S, Paavonsalo S, Heinolainen K, Lackman M, Ranta A, Hemanthakumar K, et al. Interplay of vascular endothelial growth factor receptors in organ-specific vessel maintenance. J Exp Med. 2022;219: pubmed publisher
Wang C, Liu J, Zhang X, Chen Q, Bai X, Hong X, et al. Role of miRNA-671-5p in Mediating Wnt/β-Catenin-Triggered Podocyte Injury. Front Pharmacol. 2021;12:784489 pubmed publisher
Estrada H, Robin J, Ozbek A, Chen Z, Marowsky A, Zhou Q, et al. High-resolution fluorescence-guided transcranial ultrasound mapping in the live mouse brain. Sci Adv. 2021;7:eabi5464 pubmed publisher
Heil J, Olsavszky V, Busch K, Klapproth K, de la Torre C, Sticht C, et al. Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation. Nat Commun. 2021;12:6963 pubmed publisher
Koch P, Sandorski K, Heil J, Schmid C, K xfc rschner S, Hoffmann J, et al. Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation. Front Physiol. 2021;12:722394 pubmed publisher
Gkatzis K, Panza P, Peruzzo S, Stainier D. Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures. elife. 2021;10: pubmed publisher
Logan T, Simon M, Rana A, Cherf G, Srivastava A, Davis S, et al. Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic. Cell. 2021;184:4651-4668.e25 pubmed publisher
Belicova L, Repnik U, Delpierre J, Gralinska E, Seifert S, Valenzuela J, et al. Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads. J Cell Biol. 2021;220: pubmed publisher
Schaffenrath J, Huang S, Wyss T, Delorenzi M, Keller A. Characterization of the blood-brain barrier in genetically diverse laboratory mouse strains. Fluids Barriers CNS. 2021;18:34 pubmed publisher
Srivastava T, Joshi T, Heruth D, Rezaiekhaligh M, Garola R, Zhou J, et al. A mouse model of prenatal exposure to Interleukin-6 to study the developmental origin of health and disease. Sci Rep. 2021;11:13260 pubmed publisher
Milich L, Choi J, Ryan C, Cerqueira S, Benavides S, Yahn S, et al. Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord. J Exp Med. 2021;218: pubmed publisher
Guimbal S, Cornuault L, Rouault P, Hollier P, Chapouly C, Bats M, et al. Mast Cells Are the Trigger of Small Vessel Disease and Diastolic Dysfunction in Diabetic Obese Mice. Arterioscler Thromb Vasc Biol. 2021;41:e193-e207 pubmed publisher
Navarro Betancourt J, Papillon J, Guillemette J, Iwawaki T, Chung C, Cybulsky A. Role of IRE1α in podocyte proteostasis and mitochondrial health. Cell Death Discov. 2020;6:128 pubmed publisher
Marsh B, Blelloch R. Single nuclei RNA-seq of mouse placental labyrinth development. elife. 2020;9: pubmed publisher
Orsenigo F, Conze L, Jauhiainen S, Corada M, Lazzaroni F, Malinverno M, et al. Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution. elife. 2020;9: pubmed publisher
Pulous F, Carnevale J, Al Yafeai Z, Pearson B, Hamilton J, HENRY C, et al. Talin-dependent integrin activation is required for endothelial proliferation and postnatal angiogenesis. Angiogenesis. 2021;24:177-190 pubmed publisher
Rundqvist H, Veliça P, Barbieri L, Gameiro P, Bargiela D, Gojkovic M, et al. Cytotoxic T-cells mediate exercise-induced reductions in tumor growth. elife. 2020;9: pubmed publisher
Eakin A, Mc Erlain T, Burke A, Eaton A, Tipping N, Allocca G, et al. Circulating Levels of Epirubicin Cause Endothelial Senescence While Compromising Metabolic Activity and Vascular Function. Front Cell Dev Biol. 2020;8:799 pubmed publisher
Devraj G, Guérit S, Seele J, Spitzer D, Macas J, Khel M, et al. HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis. Acta Neuropathol. 2020;140:183-208 pubmed publisher
Mao C, Lee M, Jhan J, Halpern A, Woodworth M, Glaser A, et al. Feature-rich covalent stains for super-resolution and cleared tissue fluorescence microscopy. Sci Adv. 2020;6:eaba4542 pubmed publisher
Dan H, Ruan T, Sampogna R. Circadian Clock Regulation of Developmental Time in the Kidney. Cell Rep. 2020;31:107661 pubmed publisher
Li M, Nishio S, Naruse C, Riddell M, Sapski S, Katsuno T, et al. Digenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome. Nat Commun. 2020;11:1343 pubmed publisher
Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, et al. Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021;117:533-546 pubmed publisher
Roth M, Enström A, Aghabeick C, Carlsson R, Genove G, Paul G. Parenchymal pericytes are not the major contributor of extracellular matrix in the fibrotic scar after stroke in male mice. J Neurosci Res. 2020;98:826-842 pubmed publisher
Elimam H, Papillon J, Guillemette J, Navarro Betancourt J, Cybulsky A. Genetic Ablation of Calcium-independent Phospholipase A2γ Exacerbates Glomerular Injury in Adriamycin Nephrosis in Mice. Sci Rep. 2019;9:16229 pubmed publisher
El Zein R, Soria A, Golib Dzib J, Rickard A, Fernandes Rosa F, Samson Couterie B, et al. Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling. Sci Rep. 2019;9:14677 pubmed publisher
Mueller P, Yang L, Ubele M, Mao G, Brandon J, Vandra J, et al. Coronary Artery Disease Risk-Associated Plpp3 Gene and Its Product Lipid Phosphate Phosphatase 3 Regulate Experimental Atherosclerosis. Arterioscler Thromb Vasc Biol. 2019;39:2261-2272 pubmed publisher
Reiterer M, Colaço R, Emrouznejad P, Jensen A, Rundqvist H, Johnson R, et al. Acute and chronic hypoxia differentially predispose lungs for metastases. Sci Rep. 2019;9:10246 pubmed publisher
Kasza I, Adler D, Nelson D, Eric Yen C, Dumas S, Ntambi J, et al. Evaporative cooling provides a major metabolic energy sink. Mol Metab. 2019;27:47-61 pubmed publisher
Diéguez Hurtado R, Kato K, Giaimo B, Nieminen Kelhä M, Arf H, Ferrante F, et al. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes. Nat Commun. 2019;10:2817 pubmed publisher
Malinverno M, Maderna C, Abu Taha A, Corada M, Orsenigo F, Valentino M, et al. Endothelial cell clonal expansion in the development of cerebral cavernous malformations. Nat Commun. 2019;10:2761 pubmed publisher
Genet G, Boyé K, Mathivet T, Ola R, Zhang F, Dubrac A, et al. Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis. Nat Commun. 2019;10:2350 pubmed publisher
Nilsson D, Heglind M, Arani Z, Enerback S. Foxc2 is essential for podocyte function. Physiol Rep. 2019;7:e14083 pubmed publisher
Benz F, Wichitnaowarat V, Lehmann M, Germano R, Mihova D, Macas J, et al. Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice. elife. 2019;8: pubmed publisher
Zhou L, Chen X, Lu M, Wu Q, Yuan Q, Hu C, et al. Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria. Kidney Int. 2019;95:830-845 pubmed publisher
Yang T, Xu G, Newton P, Chagin A, Mkrtchian S, Carlström M, et al. Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders. Br J Anaesth. 2019;122:350-360 pubmed publisher
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Takahashi M, Tamura M, Sato S, Kawakami K. Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele. Dis Model Mech. 2018;11: pubmed publisher
Ouarné M, Bouvard C, Boneva G, Mallet C, Ribeiro J, Desroches Castan A, et al. BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer. J Exp Clin Cancer Res. 2018;37:209 pubmed publisher
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product information
brand :
R&D Systems
master code :
AF1556
SKU :
AF1556
product name :
Mouse Podocalyxin Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse Podocalyxin Antibody from R&D Systems is a goat polyclonal antibody to Podocalyxin Like. This antibody reacts with human,mouse,rat,transgenic mouse,xenograft. The Mouse Podocalyxin Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Flow Cytometry,CyTOF-ready.
target :
Podocalyxin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 5-15 ug/mL, CyTOF-ready
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Podocalyxin, Ser21-Arg402, Accession # Q9R0M4
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse,Xenograft
specificity :
Detects mouse Podocalyxin in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Podocalyxin and rhEndoglycan is observed.
gene symbol :
PODXL
top caption :
Detection of Mouse Podocalyxin antibody by Western Blot.
accessionNumbers :
Q9R0M4
applications :
Flow Cytometry,CyTOF-ready,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
499 USD
alt names :
GCTM, Gp200MGC138240, PCLP, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, POD XL, podocalyxin-like, Podocalyxin-like protein 1, PODXL
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.