Mouse GDF-8/Myostatin Propeptide Antibody | R&D Systems AF1539 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse GDF-8/Myostatin Propeptide Antibody

catalog :

AF1539

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, neutralization, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 3

Reference
Koch C, Buono S, Menuet A, Robe A, Djeddi S, Kretz C, et al. Myostatin: a Circulating Biomarker Correlating with Disease in Myotubular Myopathy Mice and Patients. Mol Ther Methods Clin Dev. 2020;17:1178-1189 pubmed publisher
Pirruccello Straub M, Jackson J, Wawersik S, Webster M, Salta L, Long K, et al. Blocking extracellular activation of myostatin as a strategy for treating muscle wasting. Sci Rep. 2018;8:2292 pubmed publisher
Miroshnychenko O, Chang W, Dragoo J. The Use of Platelet-Rich and Platelet-Poor Plasma to Enhance Differentiation of Skeletal Myoblasts: Implications for the Use of Autologous Blood Products for Muscle Regeneration. Am J Sports Med. 2017;45:945-953 pubmed publisher

product information

brand :

R&D Systems

master code :

AF1539

SKU :

AF1539

product name :

Mouse GDF-8/Myostatin Propeptide Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Mouse GDF-8/Myostatin Propeptide Antibody from R&D Systems is a sheep polyclonal antibody to GDF-8/Myostatin. This antibody reacts with human,mouse,transgenic mouse. The Mouse GDF-8/Myostatin Propeptide Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Neutralization.

target :

GDF-8/Myostatin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Neutralization 10-30 ug/mL

host :

Sheep

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse GDF-8/Myostatin Propeptide, Asn25-Ser265, Accession # O08689

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects GDF-8/Myostatin Propeptide in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with mature recombinant mouse (rm) GDF-8 is observed and less than 5% cross-reactivity with mature rmGDF-1, -3, -5, -6, -7, -9, and recombinant human GDF-11 is observed.

gene symbol :

MSTN

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

GDF-8 Propeptide Inhibition of GDF-8/Myostatin-induced Hemoglobin Expression and Neutralization by Mouse GDF-8 Propeptide Antibody.

accessionNumbers :

O08689

applications :

Neutralization,Immunoprecipitation,Western Blot

USD :

459 USD

alt names :

GDF8, GDF-8, GDF8growth differentiation factor 8, growth/differentiation factor 8, MSLHP, MSTN, Myostatin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage