Mouse Frizzled-6 Antibody | R&D Systems AF1526 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Frizzled-6 Antibody

catalog :

AF1526

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:200; loading ...; fig 8a	Kindt K, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, et al. EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021;12:2861 pubmed publisher
	Tower Z, Chang H. Improved method for detecting protein-protein interactions using proximity ligation assay. bioRxiv. 2024;: pubmed publisher
	Cetera M, Sharan R, Hayward Lara G, Phillips B, Biswas A, Halley M, et al. Region-specific reversal of epidermal planar polarity in the fancy rosette mouse. bioRxiv. 2023;: pubmed publisher
	Ozono Y, Tamura A, Nakayama S, Herawati E, Hanada Y, Ohata K, et al. Daple deficiency causes hearing loss in adult mice by inducing defects in cochlear stereocilia and apical microtubules. Sci Rep. 2021;11:20224 pubmed publisher
	Basta L, Hill Oliva M, Paramore S, Sharan R, Goh A, Biswas A, et al. New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo. Development. 2021;148: pubmed publisher
	Landin Malt A, Clancy S, Hwang D, Liu A, Smith C, Smith M, et al. Non-Canonical Wnt Signaling Regulates Cochlear Outgrowth and Planar Cell Polarity via Gsk3β Inhibition. Front Cell Dev Biol. 2021;9:649830 pubmed publisher
	Nakayama S, Yano T, Namba T, Konishi S, Takagishi M, Herawati E, et al. Planar cell polarity induces local microtubule bundling for coordinated ciliary beating. J Cell Biol. 2021;220: pubmed publisher
	Stahley S, Basta L, Sharan R, Devenport D. Celsr1 adhesive interactions mediate the asymmetric organization of planar polarity complexes. elife. 2021;10: pubmed publisher
	Moon K, Ma J, Min H, Koo H, Kim H, Ko H, et al. Dysregulation of sonic hedgehog signaling causes hearing loss in ciliopathy mouse models. elife. 2020;9: pubmed publisher
	Landin Malt A, Hogan A, Smith C, Madani M, Lu X. Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling. J Cell Biol. 2020;219: pubmed publisher
	Ghimire S, Deans M. Frizzled3 and Frizzled6 Cooperate with Vangl2 to Direct Cochlear Innervation by Type II Spiral Ganglion Neurons. J Neurosci. 2019;39:8013-8023 pubmed publisher
	George L, Mitra A, Thimraj T, Irmler M, Vishweswaraiah S, Lunding L, et al. Transcriptomic analysis comparing mouse strains with extreme total lung capacities identifies novel candidate genes for pulmonary function. Respir Res. 2017;18:152 pubmed publisher
	Wen J, Tao H, Lau K, Liu H, Simmons C, Sun Y, et al. Cell and Tissue Scale Forces Coregulate Fgfr2-Dependent Tetrads and Rosettes in the Mouse Embryo. Biophys J. 2017;112:2209-2218 pubmed publisher
	Oozeer F, Yates L, Dean C, Formstone C. A role for core planar polarity proteins in cell contact-mediated orientation of planar cell division across the mammalian embryonic skin. Sci Rep. 2017;7:1880 pubmed publisher
	Chang H, Smallwood P, Williams J, Nathans J. The spatio-temporal domains of Frizzled6 action in planar polarity control of hair follicle orientation. Dev Biol. 2016;409:181-193 pubmed publisher

product information

master code :

AF1526

SKU :

AF1526

product name :

Mouse Frizzled-6 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Frizzled-6 Antibody from R&D Systems is a goat polyclonal antibody to Frizzled-6. This antibody reacts with human,mouse. The Mouse Frizzled-6 Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow Cytometry,Western Blot,CyTOF-ready.

target :

Frizzled-6

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Frizzled-6, His19-Val153, Accession # Q61089

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects mouse Frizzled-6 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human Frizzled-6 is observed, and less than 1% cross-reactivity with recombinant mouse (rm) Frizzled-1, rmFrizzled-2, rmFrizzled-3, rmFrizzled-4, rmFrizzled-7, rmFrizzled-8, and rmFrizzled-9 is observed.

gene symbol :

FZD6

top caption :

Detection of Mouse Frizzled-6 by Immunocytochemistry/Immunofluorescence

accessionNumbers :

Q61089

applications :

Immunocytochemistry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow Cytometry,Western Blot,CyTOF-ready

USD :

519 USD

alt names :

frizzled (Drosophila) homolog 6, frizzled homolog 6 (Drosophila), frizzled-6, Frizzled6, fz-6, FZ6, FZD6, HFZ6, seven transmembrane helix receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage