product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ULBP-3 Antibody
catalog :
AF1517
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1
Sturgill E, Malouli D, Hansen S, Burwitz B, Seo S, Schneider C, et al. Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus. PLoS Pathog. 2016;12:e1005868 pubmed publisher
  • flow cytometry; human; fig s1
Bauman Y, Drayman N, Ben nun Shaul O, Vitenstein A, Yamin R, Ophir Y, et al. Downregulation of the stress-induced ligand ULBP1 following SV40 infection confers viral evasion from NK cell cytotoxicity. Oncotarget. 2016;7:15369-81 pubmed publisher
Seller A, Tegeler C, Mauermann J, Schreiber T, Hagelstein I, Liebel K, et al. Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome. Int J Mol Sci. 2024;25: pubmed publisher
Joung J, Kirchgatterer P, Singh A, Cho J, Nety S, Larson R, et al. CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nat Commun. 2022;13:1606 pubmed publisher
Weil S, Memmer S, Lechner A, Huppert V, Giannattasio A, Becker T, et al. Natural Killer Group 2D Ligand Depletion Reconstitutes Natural Killer Cell Immunosurveillance of Head and Neck Squamous Cell Carcinoma. Front Immunol. 2017;8:387 pubmed publisher
Giannattasio A, Weil S, Kloess S, Ansari N, Stelzer E, Cerwenka A, et al. Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids. BMC Cancer. 2015;15:351 pubmed publisher
Fujita H, Hatanaka Y, Sutoh Y, Suzuki Y, Oba K, Hatanaka K, et al. Immunohistochemical validation and expression profiling of NKG2D ligands in a wide spectrum of human epithelial neoplasms. J Histochem Cytochem. 2015;63:217-27 pubmed publisher
product information
master code :
AF1517
SKU :
AF1517
product name :
Human ULBP-3 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human ULBP-3 Antibody from R&D Systems is a goat polyclonal antibody to ULBP-3. This antibody reacts with human. The Human ULBP-3 Antibody has been validated for the following applications: ELISA Capture,ELISA Development (Capture),Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Blockade of Receptor-ligand Interaction.
target :
ULBP-3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human ULBP-3, Gly27-Pro216, Accession # NP_078794
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human ULBP-3 in direct ELISAs and Western blots. In these formats, approximately 5% cross-reactivity with recombinant human (rh) ULBP-2 is observed and less than 1% cross-reactivity with rhULBP-1 is observed.
gene symbol :
ULBP3
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human ULBP-3 by Flow Cytometry
accessionNumbers :
NP_078794
applications :
ELISA Capture,ELISA Development (Capture),Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Blockade of Receptor-ligand Interaction
USD :
479 USD
alt names :
NKG2D ligand 3, RAET1N, UL16 binding protein 3, ULBP3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.