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company name :
R&D Systems
product type :
antibody
product name :
Mouse/Rat MMP-2 Antibody
catalog :
AF1488
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 17
Reference
Wang D, Saleem S, Sullivan R, Zhao T, Reed G. Differences in Acute Expression of Matrix Metalloproteinases-9, 3, and 2 Related to the Duration of Brain Ischemia and Tissue Plasminogen Activator Treatment in Experimental Stroke. Int J Mol Sci. 2024;25: pubmed publisher
Fu Y, Liu H, Li K, Wei P, Alam N, Deng J, et al. C-reactive protein deficiency ameliorates experimental abdominal aortic aneurysms. Front Immunol. 2023;14:1233807 pubmed publisher
Fu W, Liu H, Wei P, Xia C, Yu Q, Tian K, et al. Genetic deficiency of protein inhibitor of activated STAT3 suppresses experimental abdominal aortic aneurysms. Front Cardiovasc Med. 2023;10:1092555 pubmed publisher
Ni L, Liu L, Zhu W, Telljohann R, Zhang J, Monticone R, et al. Inflammatory Role of Milk Fat Globule-Epidermal Growth Factor VIII in Age-Associated Arterial Remodeling. J Am Heart Assoc. 2022;11:e022574 pubmed publisher
Liu H, Tian K, Xia C, Wei P, Xu B, Fu W, et al. Kunming mouse strain is less susceptible to elastase-induced abdominal aortic aneurysms. Animal Model Exp Med. 2022;5:72-80 pubmed publisher
Tian K, Xia C, Liu H, Xu B, Wei P, Fu W, et al. Temporal and Quantitative Analysis of Aortic Immunopathologies in Elastase-Induced Mouse Abdominal Aortic Aneurysms. J Immunol Res. 2021;2021:6297332 pubmed publisher
Chun C, Qi X, Wang F, Madrid K, Saldarriaga L, Fisch M, et al. Nicotine Exacerbates TAAD Formation Induced by Smooth Muscle-Specific Deletion of the TGF-β Receptor 2. J Immunol Res. 2021;2021:6880036 pubmed publisher
Grol M, Haelterman N, Lim J, Munivez E, Archer M, Hudson D, et al. Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta. elife. 2021;10: pubmed publisher
Li K, Zhou Z, Li J, Xiang R. miR-146b Functions as an Oncogene in Oral Squamous Cell Carcinoma by Targeting HBP1. Technol Cancer Res Treat. 2020;19:1533033820959404 pubmed publisher
Jeong S, Cho M, Ko N, Kim S, Jung I, Min J, et al. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm. Exp Mol Med. 2020;52:1587-1601 pubmed publisher
Lu C, Lai S, Lee H, Chien H, Lan K, Chen K. Matrix metalloproteinases activation in Toxocara canis induced pulmonary pathogenesis. J Microbiol Immunol Infect. 2021;54:1147-1153 pubmed publisher
Gou X, Xue Y, Zheng H, Yang G, Chen S, Chen Z, et al. Gelatinases Cleave Dentin Sialoprotein Intracellularly. Front Physiol. 2020;11:686 pubmed publisher
Zhang H, Liao M, Cao M, Qiu Z, Yan X, Zhou Y, et al. ATRQβ-001 Vaccine Prevents Experimental Abdominal Aortic Aneurysms. J Am Heart Assoc. 2019;8:e012341 pubmed publisher
Liu L, Li H, Nie S, Shen M, Hu J, Xie M. Tea Polysaccharide Prevents Colitis-Associated Carcinogenesis in Mice by Inhibiting the Proliferation and Invasion of Tumor Cells. Int J Mol Sci. 2018;19: pubmed publisher
Lin C, Jeng J, Wu C, Hsieh S, Huang G, Leung W, et al. Chemopreventive Potential of 2,3,5,4'-Tetrahydroxystilbene-2-O-?-D-glucoside on the Formation of Aberrant Crypt Foci in Azoxymethane-Induced Colorectal Cancer in Rats. Biomed Res Int. 2017;2017:3634915 pubmed publisher
Chen P, Tang C, Lin L, Tsai C, Chu C, Lin T, et al. Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression. J Hematol Oncol. 2017;10:33 pubmed publisher
Liao M, Yang P, Wang F, Berceli S, Ali Y, Chan K, et al. Smooth muscle cell-specific Tgfbr1 deficiency attenuates neointimal hyperplasia but promotes an undesired vascular phenotype for injured arteries. Physiol Rep. 2016;4: pubmed
product information
master code :
AF1488
SKU :
AF1488
product name :
Mouse/Rat MMP-2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse/Rat MMP-2 Antibody from R&D Systems is a goat polyclonal antibody to MMP-2. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse/Rat MMP-2 Antibody has been validated for the following applications: Western Blot,Zymography,Immunohistochemistry,ELISA Development (Capture),Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Immunoprecipitation.
target :
MMP-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse MMP-2, Ile34-Cys662, Accession # P33434
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse and rat MMP-2 in direct ELISAs and Western blots. In direct ELISAs, less than 40% cross-reactivity with recombinant human MMP-2 is observed and less than 1% cross-reactivity with recombinant mouse (rm) MMP-3 and rmMMP-9 is observed.
gene symbol :
MMP2
top caption :
MMP-2 antibody in Mouse Thymus by Immunohistochemistry (IHC-Fr).
accessionNumbers :
P33434
applications :
Western Blot,Zymography,Immunohistochemistry,ELISA Development (Capture),Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Immunoprecipitation
USD :
499 USD
alt names :
72 kDa gelatinase, CLG4, CLG4A72 kDa type IV collagenase, collagenase type IV-A, EC 3.4.24, EC 3.4.24.24, Gelatinase A, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase), matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IVcollagenase), Matrix metalloproteinase-2, matrix metalloproteinase-II, MMP2, MMP-2, MMP-II, MONA, neutrophil gelatinase, TBE-1matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.